D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 72 Citations 15,951 235 World Ranking 13755 National Ranking 7231

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Enzyme

His primary scientific interests are in Internal medicine, Endocrinology, Renin–angiotensin system, Genetically modified mouse and Transgene. His work on Internal medicine deals in particular with Angiotensin II, Blood pressure, Endothelium, Leptin and Losartan. His research in Endocrinology focuses on subjects like Gene expression, which are connected to Adrenal gland.

His work on Plasma renin activity and Afferent arterioles as part of general Renin–angiotensin system study is frequently linked to Glial fibrillary acidic protein, therefore connecting diverse disciplines of science. His Genetically modified mouse study incorporates themes from Molecular biology, Amygdala, Central nervous system and Ratón. The Transgene study combines topics in areas such as Endocrine system, Thirst and Cell biology.

His most cited work include:

  • Ghrelin Inhibits Proinflammatory Responses and Nuclear Factor-κB Activation in Human Endothelial Cells (442 citations)
  • Minireview: Overview of the Renin-Angiotensin System—An Endocrine and Paracrine System (412 citations)
  • Lethal Infection of K18-hACE2 Mice Infected with Severe Acute Respiratory Syndrome Coronavirus (395 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Internal medicine, Endocrinology, Renin–angiotensin system, Angiotensin II and Genetically modified mouse. His study in Blood pressure, Endothelial dysfunction, Angiotensin II receptor type 1, Vasodilation and Vascular smooth muscle is carried out as part of his studies in Internal medicine. Curt D. Sigmund has researched Endocrinology in several fields, including Receptor, Peroxisome proliferator-activated receptor and Gene expression.

His Renin–angiotensin system study which covers Cell biology that intersects with Transcription factor. His Genetically modified mouse research is multidisciplinary, relying on both Molecular biology, Endogeny, Central nervous system and Downregulation and upregulation. His Molecular biology research is multidisciplinary, incorporating perspectives in Enhancer, Transcription, Messenger RNA and Exon.

He most often published in these fields:

  • Internal medicine (68.38%)
  • Endocrinology (66.24%)
  • Renin–angiotensin system (36.54%)

What were the highlights of his more recent work (between 2017-2021)?

  • Internal medicine (68.38%)
  • Endocrinology (66.24%)
  • Blood pressure (16.03%)

In recent papers he was focusing on the following fields of study:

His main research concerns Internal medicine, Endocrinology, Blood pressure, Preeclampsia and Renin–angiotensin system. The various areas that Curt D. Sigmund examines in his Internal medicine study include Wild type and Cardiology. He works mostly in the field of Endocrinology, limiting it down to topics relating to Receptor and, in certain cases, Regulator.

His Blood pressure research incorporates themes from Transcription factor, Bioinformatics and Gene isoform. His Preeclampsia study integrates concerns from other disciplines, such as Copeptin, Vasopressin and First trimester. He has included themes like Polydipsia, Hypothalamus and Gene, Transgene in his Renin–angiotensin system study.

Between 2017 and 2021, his most popular works were:

  • Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology. (230 citations)
  • Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice (21 citations)
  • Elevated vasopressin in pregnant mice induces T-helper subset alterations consistent with human preeclampsia (20 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Enzyme

Curt D. Sigmund mostly deals with Internal medicine, Endocrinology, Receptor, Nitric oxide and Angiotensin II. The study of Internal medicine is intertwined with the study of Preeclampsia in a number of ways. His study of Leptin is a part of Endocrinology.

He focuses mostly in the field of Receptor, narrowing it down to topics relating to Vasopressin and, in certain cases, Arginine vasopressin receptor 2, Immune system and Fetus. His studies in Nitric oxide integrate themes in fields like Vascular smooth muscle and Vasodilation. In his research, Transgene, Central nervous system and Neuroscience is intimately related to Renin–angiotensin system, which falls under the overarching field of Angiotensin II.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Ghrelin Inhibits Proinflammatory Responses and Nuclear Factor-κB Activation in Human Endothelial Cells

Wei Gen Li;Dan Gavrila;Xuebo Liu;Lixing Wang.
Circulation (2004)

630 Citations

Minireview: Overview of the Renin-Angiotensin System—An Endocrine and Paracrine System

Julie L. Lavoie;Curt D. Sigmund.
Endocrinology (2003)

625 Citations

Viewpoint: Are Studies in Genetically Altered Mice Out of Control?

Curt D. Sigmund.
Arteriosclerosis, Thrombosis, and Vascular Biology (2000)

498 Citations

Lethal Infection of K18-hACE2 Mice Infected with Severe Acute Respiratory Syndrome Coronavirus

Paul B. McCray;Lecia Pewe;Christine Wohlford-Lenane;Melissa Hickey.
Journal of Virology (2007)

459 Citations

Abnormal Coronary Function in Mice Deficient in α1H T-type Ca2+ Channels

Chien Chang Chen;Kathryn G. Lamping;Kathryn G. Lamping;Daniel W. Nuno;Daniel W. Nuno;Rita Barresi.
Science (2003)

378 Citations

Contrasting blood pressure effects of obesity in leptin-deficient ob/ob mice and agouti yellow obese mice.

Allyn L. Mark;Richard A. Shaffer;Marcelo L.G. Correia;Donald A. Morgan.
Journal of Hypertension (1999)

325 Citations

Increased Superoxide and Vascular Dysfunction in CuZnSOD-Deficient Mice

Sean P. Didion;Michael J. Ryan;Lisa A. Didion;Pamela E. Fegan.
Circulation Research (2002)

289 Citations

Differential expression of angiotensin receptor 1A and 1B in mouse.

J. M. Burson;G. Aguilera;K. W. Gross;C. D. Sigmund.
American Journal of Physiology-endocrinology and Metabolism (1994)

286 Citations

Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology.

Steven J. Forrester;George W. Booz;Curt D. Sigmund;Thomas M. Coffman.
Physiological Reviews (2018)

285 Citations

Antibiotic resistance mutations in 16S and 23S ribosomal RNA genes of Escherichia coli

Curt D. Sigmund;Mohamed Ettayebi;Edward A. Morgan.
Nucleic Acids Research (1984)

274 Citations

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