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Medicine

D-Index
89
Citations
24392
World Ranking
12838
National Ranking
6565

Overview

Curt D. Sigmund is affiliated with the Medical College of Wisconsin in the United States. Their research spans multiple areas within medicine and biochemistry, particularly focusing on the molecular and physiological aspects of cardiovascular health and metabolic regulation.

The main fields of study addressed in Sigmund's work include Medicine and Biochemistry, Genetics and Molecular Biology. Their subfields of expertise are Molecular Biology, Cardiology and Cardiovascular Medicine, Physiology, Endocrinology, Diabetes and Metabolism, and Endocrine and Autonomic Systems.

The key topics observed in Sigmund's publications cover:

  • Renin-Angiotensin System Studies
  • Hormonal Regulation and Hypertension
  • Receptor Mechanisms and Signaling
  • Adipose Tissue and Metabolism
  • Regulation of Appetite and Obesity
  • Birth, Development, and Health
  • Eicosanoids and Hypertension Pharmacology

Sigmund's recent papers include the following:

  • The Renin-Angiotensin System in the Central Nervous System and Its Role in Blood Pressure Regulation, 2020, Current Hypertension Reports
  • Single-Nucleus RNA Sequencing of the Hypothalamic Arcuate Nucleus of C57BL/6J Mice After Prolonged Diet-Induced Obesity, 2020, Hypertension
  • Role of the Peroxisome Proliferator Activated Receptors in Hypertension, 2021, Circulation Research
  • Report of the National Heart, Lung, and Blood Institute Working Group on Hypertension, 2020, Hypertension
  • Failure to vasodilate in response to salt loading blunts renal blood flow and causes salt-sensitive hypertension, 2020, Cardiovascular Research

Frequent co-authors collaborating with Sigmund include:

  • Justin L. Grobe
  • Pablo Nakagawa
  • Daniel Brozoski
  • Ko-Ting Lu
  • John J. Reho

The scientist commonly publishes in a range of venues, with the most frequent being:

  • Hypertension
  • The FASEB Journal
  • Physiology
  • American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  • Function

Best Publications

  • Lethal Infection of K18-hACE2 Mice Infected with Severe Acute Respiratory Syndrome Coronavirus

    Paul B. McCray;Lecia Pewe;Christine Wohlford-Lenane;Melissa Hickey

  • Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology.

    Steven J. Forrester;George W. Booz;Curt D. Sigmund;Thomas M. Coffman

  • Minireview: Overview of the Renin-Angiotensin System—An Endocrine and Paracrine System

    Julie L. Lavoie;Curt D. Sigmund

  • Ghrelin Inhibits Proinflammatory Responses and Nuclear Factor-κB Activation in Human Endothelial Cells

    Wei Gen Li;Dan Gavrila;Xuebo Liu;Lixing Wang

  • Viewpoint: Are Studies in Genetically Altered Mice Out of Control?

    Curt D. Sigmund

  • Abnormal Coronary Function in Mice Deficient in α1H T-type Ca2+ Channels

    Chien Chang Chen;Kathryn G. Lamping;Kathryn G. Lamping;Daniel W. Nuno;Daniel W. Nuno;Rita Barresi

  • Contrasting blood pressure effects of obesity in leptin-deficient ob/ob mice and agouti yellow obese mice.

    Allyn L. Mark;Richard A. Shaffer;Marcelo L.G. Correia;Donald A. Morgan

  • Increased Superoxide and Vascular Dysfunction in CuZnSOD-Deficient Mice

    Sean P. Didion;Michael J. Ryan;Lisa A. Didion;Pamela E. Fegan

  • Differential expression of angiotensin receptor 1A and 1B in mouse.

    J. M. Burson;G. Aguilera;K. W. Gross;C. D. Sigmund

  • Antibiotic resistance mutations in 16S and 23S ribosomal RNA genes of Escherichia coli

    Curt D. Sigmund;Mohamed Ettayebi;Edward A. Morgan

  • Cerebral Vascular Dysfunction Mediated by Superoxide in Hyperhomocysteinemic Mice

    Sanjana Dayal;Erland Arning;Teodoro Bottiglieri;Rainer H. Böger

  • Endothelial Dysfunction and Elevation of S-Adenosylhomocysteine in Cystathionine β-Synthase–Deficient Mice

    Sanjana Dayal;Teodoro Bottiglieri;Erland Arning;Nobuyo Maeda

  • Oxidation of CaMKII determines the cardiotoxic effects of aldosterone

    B. Julie He;Mei Ling A. Joiner;Madhu V. Singh;Elizabeth D. Luczak

  • PPARγ Agonist Rosiglitazone Improves Vascular Function and Lowers Blood Pressure in Hypertensive Transgenic Mice

    Michael J. Ryan;Sean P. Didion;Satya Mathur;Frank M. Faraci

  • Antibiotic resistance mutations in ribosomal RNA genes of Escherichia coli.

    Curt D. Sigmund;Mohamed Ettayebi;Angela Borden;Edward A. Morgan

  • Expression of the DBA/2J Ren-2 gene in the adrenal gland of transgenic mice.

    J J Mullins;C D Sigmund;C Kane-Haas;K W Gross

  • Hypothalamic ERK mediates the anorectic and thermogenic sympathetic effects of leptin.

    Kamal Rahmouni;Curt D. Sigmund;William G. Haynes;Allyn L. Mark

  • Overexpression of acid-sensing ion channel 1a in transgenic mice increases acquired fear-related behavior.

    John A. Wemmie;Matthew W. Coryell;Candice C. Askwith;Ejvis Lamani

  • The Kidney Androgen-regulated Protein Promoter Confers Renal Proximal Tubule Cell-specific and Highly Androgen-responsive Expression on the Human Angiotensinogen Gene in Transgenic Mice*

    Yueming Ding;Robin L. Davisson;Dianne O. Hardy;Li-Ji Zhu

  • The Brain Renin-Angiotensin System Contributes to the Hypertension in Mice Containing Both the Human Renin and Human Angiotensinogen Transgenes

    Robin L. Davisson;Gongyu Yang;Terry G. Beltz;Martin D. Cassell

Frequent Co-Authors

Frank M. Faraci
Frank M. Faraci University of Iowa
Kamal Rahmouni
Kamal Rahmouni University of Iowa Health Care
Martin D. Cassell
Martin D. Cassell University of Iowa
Robert M. Weiss
Robert M. Weiss University of Iowa
Donald D. Heistad
Donald D. Heistad University of Iowa
Nobuyo Maeda
Nobuyo Maeda University of North Carolina at Chapel Hill
Alan Kim Johnson
Alan Kim Johnson University of Iowa
Robin L. Davisson
Robin L. Davisson Cornell University
Terry G. Beltz
Terry G. Beltz University of Iowa
Anne E. Kwitek
Anne E. Kwitek Medical College of Wisconsin

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