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Akiyoshi Fukamizu

Akiyoshi Fukamizu

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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
96
Citations
34357
World Ranking
1818
National Ranking
102

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Akiyoshi Fukamizu is affiliated with the University of Tsukuba in Japan. Their work spans multiple fields within the biological and medical sciences, focusing on molecular mechanisms and disease-related research.

The scientist's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader areas, their research covers several subfields such as:

  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Oncology
  • Immunology

The main topics addressed in their publications are:

  • Cancer-related gene regulation
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Renin-Angiotensin System Studies
  • RNA Research and Splicing
  • Genomics and Chromatin Dynamics

Notable peer-reviewed papers authored or co-authored by Akiyoshi Fukamizu include:

  • "m 6 A-mediated alternative splicing coupled with nonsense-mediated mRNA decay regulates SAM synthetase homeostasis" (2021), The EMBO Journal
  • "Roles of protein arginine methyltransferase 1 (PRMT1) in brain development and disease" (2020), Biochimica et Biophysica Acta (BBA) - General Subjects
  • "Identification of a novel nucleolar protein complex required for mitotic chromosome segregation through centromeric accumulation of Aurora B" (2020), Nucleic Acids Research
  • "Age-dependent decline in remyelination capacity is mediated by apelin-APJ signaling" (2021), Nature Aging
  • "Transcriptomic Evaluation of Pulmonary Fibrosis-Related Genes: Utilization of Transgenic Mice with Modifying p38 Signal in the Lungs" (2020), International Journal of Molecular Sciences

Frequent publication venues for their research outputs include:

  • Journal of Biological Chemistry
  • The Journal of Biochemistry
  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • The EMBO Journal
  • Biochimica et Biophysica Acta (BBA) - General Subjects

Akiyoshi Fukamizu has collaborated recurrently with several researchers in their field. Co-authors with whom they have published extensively include:

  • Jun-Dal Kim
  • Koichiro Kako
  • Hiroaki Daitoku
  • Junji Ishida
  • Kazuya Murata

Best Publications

  • Angiotensin-converting enzyme 2 protects from severe acute lung failure

    Yumiko Imai;Keiji Kuba;Shuan Rao;Yi Huan

  • ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation

    Tatsuo Hashimoto;Thomas Perlot;Ateequr Rehman;Ateequr Rehman;Jean Trichereau

  • Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning

    Tatsuya Yoshizawa;Yuki Handa;Yoshikatsu Uematsu;Shu Takeda

  • Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II

    Yunzeng Zou;Hiroshi Akazawa;Yingjie Qin;Masanori Sano

  • Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity

    Hiroaki Daitoku;Mitsutoki Hatta;Hitomi Matsuzaki;Satoko Aratani

  • Adipose angiotensinogen is involved in adipose tissue growth and blood pressure regulation

    Florence Massiéra;May Bloch-Faure;Debbie Ceiler;Kazuo Murakami

  • Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription

    Yasutake Katoh;Ken Itoh;Eisaku Yoshida;Makoto Miyagishi

  • Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation

    Hitomi Matsuzaki;Hiroaki Daitoku;Mitsutoki Hatta;Keiji Tanaka

  • Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo

    Junji Ishida;Tatsuo Hashimoto;Tatsuo Hashimoto;Yasumi Hashimoto;Shiro Nishiwaki

  • Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation

    Hitomi Matsuzaki;Hiroaki Daitoku;Mitsutoki Hatta;Hisanori Aoyama

  • Identification and functional analysis of endothelial tip cell–enriched genes

    Raquel del Toro;Raquel del Toro;Claudia Prahst;Claudia Prahst;Thomas Mathivet;Thomas Mathivet;Geraldine Siegfried

  • Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt.

    Kazuyuki Yamagata;Hiroaki Daitoku;Yuta Takahashi;Kana Namiki

  • Epigenetic Control of rDNA Loci in Response to Intracellular Energy Status

    Akiko Murayama;Kazuji Ohmori;Akiko Fujimura;Hiroshi Minami

  • SREBPs suppress IRS-2-mediated insulin signalling in the liver

    Tomohiro Ide;Hitoshi Shimano;Naoya Yahagi;Takashi Matsuzaka

  • Angiotensinogen-deficient mice with hypotension.

    K. Tanimoto;F. Sugiyama;Y. Goto;J. Ishida

  • Angiotensin II Type 1a Receptor-deficient Mice with Hypotension and Hyperreninemia

    Takeshi Sugaya;Shin-ichiro Nishimatsu;Keiji Tanimoto;Eriko Takimoto

  • Bile acids regulate gluconeogenic gene expression via small heterodimer partner-mediated repression of hepatocyte nuclear factor 4 and Foxo1.

    Kazuyuki Yamagata;Hiroaki Daitoku;Yoko Shimamoto;Hitomi Matsuzaki

  • Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR.

    Hiroaki Daitoku;Kazuyuki Yamagata;Hitomi Matsuzaki;Mitsutoki Hatta

  • The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice

    Shigetomo Fukuhara;Szandor Simmons;Shunsuke Kawamura;Asuka Inoue

  • Regulation of FoxO transcription factors by acetylation and protein-protein interactions.

    Hiroaki Daitoku;Jun-ichi Sakamaki;Akiyoshi Fukamizu

Frequent Co-Authors

Kazuo Murakami
Kazuo Murakami University of Tsukuba
Katsutoshi Goto
Katsutoshi Goto University of Tsukuba
Sadao Kimura
Sadao Kimura Chiba University
Ikuro Maruyama
Ikuro Maruyama Kagoshima University
Masayuki Yamamoto
Masayuki Yamamoto Tohoku University
James Douglas Engel
James Douglas Engel University of Michigan–Ann Arbor
Kusuki Nishioka
Kusuki Nishioka St. Marianna University School of Medicine
Makoto Miyagishi
Makoto Miyagishi National Institute of Advanced Industrial Science and Technology
Josef M. Penninger
Josef M. Penninger University of British Columbia
Masatsugu Ema
Masatsugu Ema Shiga University of Medical Science

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