2026 Ikuro Maruyama: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	90	2447	2240	151	139	569	27245
Medicine	90	12257	11532	364	344	622	28096

Overview

Ikuro Maruyama is affiliated with Kagoshima University in Japan and has contributed extensively to the field of medicine, focusing particularly on immunology, epidemiology, molecular biology, neurology, and physiology. Their research encompasses a range of topics relevant to disease mechanisms and clinical outcomes.

Maruyama's recent papers include:

Endotheliopathy in septic conditions: mechanistic insight into intravascular coagulation (2021, Critical Care)
Identification of distinct N-glycosylation patterns on extracellular vesicles from small-cell and non-small-cell lung cancer cells (2022, Journal of Biological Chemistry)
Glycometabolic Regulation of the Biogenesis of Small Extracellular Vesicles (2020, Cell Reports)
Circulating Syndecan-1 as a Predictor of Persistent Thrombocytopenia and Lethal Outcome: A Population Study of Patients With Suspected Sepsis Requiring Intensive Care (2021, Frontiers in Cardiovascular Medicine)
Preconditioning Exercise in Rats Attenuates Early Brain Injury Resulting from Subarachnoid Hemorrhage by Reducing Oxidative Stress, Inflammation, and Neuronal Apoptosis (2021, Molecular Neurobiology)

The scientist's frequent coauthors include:

Takashi Ito (15 coauthored works)
Shotaro Otsuka (14 coauthored works)
Seiya Takada (13 coauthored works)
Harutoshi Sakakima (12 coauthored works)
Kazuki Nakanishi (10 coauthored works)

Maruyama has published multiple articles in key journals such as:

International Journal of Molecular Sciences (5 publications)
Thrombosis Journal (4 publications)
Scientific Reports (4 publications)
In Vivo (2 publications)
Aging (2 publications)

The main fields of study that Maruyama focuses on include:

Medicine (59 publications)
Immunology (10 publications)
Epidemiology (10 publications)
Molecular Biology (9 publications)
Neurology (8 publications)
Physiology (6 publications)

Their research topics cover a range of medical and biological mechanisms, such as:

Neutrophil, Myeloperoxidase and Oxidative Mechanisms (12 publications)
Sepsis Diagnosis and Treatment (10 publications)
Venous Thromboembolism Diagnosis and Management (10 publications)
Neuroinflammation and Neurodegeneration Mechanisms (8 publications)
Trauma, Hemostasis, Coagulopathy, Resuscitation (6 publications)
Advanced Glycation End Products research (6 publications)
Diet, Metabolism, and Disease (6 publications)

Best Publications

High mobility group box 1 protein interacts with multiple Toll-like receptors

Jong Sung Park;Fabia Gamboni-Robertson;Qianbin He;Daiva Svetkauskaite

1311
Citations
Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: results of a phase III, randomized, double-blind clinical trial

H. Saito;I. Maruyama;S. Shimazaki;Y. Yamamoto

789
Citations
The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism

Kazuhiro Abeyama;David M. Stern;Yuji Ito;Ko-ichi Kawahara

764
Citations
High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine.

Noboru Taniguchi;Ko-Ichi Kawahara;Kazunori Yone;Teruto Hashiguchi

714
Citations
CHRONIC INFLAMMATORY ARTHROPATHY ASSOCIATED WITH HTLV-I

Kusuki Nishioka;Ikuro Maruyama;Kazuto Sato;Isao Kitajima

588
Citations
Thrombomodulin is found on endothelium of arteries, veins, capillaries, and lymphatics, and on syncytiotrophoblast of human placenta

I Maruyama;C E Bell;P W Majerus

578
Citations
Contributions of high mobility group box protein in experimental and clinical acute lung injury

Hiroshi Ueno;Tomoyuki Matsuda;Satoru Hashimoto;Fumimasa Amaya

504
Citations
Greatly raised vascular endothelial growth factor (VEGF) in POEMS syndrome

Osamu Watanabe;Kimiyoshi Arimura;Isao Kitajima;Mitsuhiro Osame

410
Citations
Overproduction of vascular endothelial growth factor/vascular permeability factor is causative in Crow-Fukase (POEMS) syndrome

Osamu Watanabe;Ikuro Maruyama;Kimiyoshi Arimura;Isao Kitajima

361
Citations
Predominant recognition of human T cell leukemia virus type I (HTLV-I) pX gene products by human CD8+ cytotoxic T cells directed against HTLV-I-infected cells.

Mari Kannagi;Shinji Harada;Ikuro Maruyama;Hidetoshi Inoko

347
Citations
Leptin promotes aggregation of human platelets via the long form of its receptor.

M Nakata;T Yada;N Soejima;I Maruyama

335
Citations
HMGB1 contributes to the development of acute lung injury after hemorrhage.

Jae Yeol Kim;Jong Sung Park;Derek Strassheim;Ivor Douglas

317
Citations
Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathy.

Tetsuya Amano;Satoshi Yamasaki;Naoko Yagishita;Kaneyuki Tsuchimochi

298
Citations
Expert consensus for the treatment of disseminated intravascular coagulation in Japan.

Hideo Wada;Hidesaku Asakura;Kohji Okamoto;Toshiaki Iba

297
Citations
Plasma concentrations and importance of High Mobility Group Box protein in the prognosis of organ failure in patients with disseminated intravascular coagulation.

Tsuyoshi Hatada;Hideo Wada;Tsutomu Nobori;Kazuhiro Okabayashi

292
Citations
Isolation and characterization of thrombomodulin from human placenta.

H H Salem;I Maruyama;H Ishii;P W Majerus

292
Citations
Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase ‘Synoviolin’

Satoshi Yamasaki;Naoko Yagishita;Takeshi Sasaki;Minako Nakazawa

286
Citations
Proteolytic Cleavage of High Mobility Group Box 1 Protein by Thrombin-Thrombomodulin Complexes

Takashi Ito;Ko-ichi Kawahara;Kohji Okamoto;Shingo Yamada

268
Citations
Enhanced expression of type I receptors for bone morphogenetic proteins during bone formation

Yasuhiro Ishidou;Isao Kitajima;Hiroya Obama;Ikuro Maruyama

242
Citations
High‐mobility group box 1 protein promotes development of microvascular thrombosis in rats

T. Ito;K. Kawahara;T. Nakamura;S. Yamada

239
Citations