What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Internal medicine
The scientist’s investigation covers issues in Protein C, Thrombin, Thrombomodulin, Biochemistry and Immunology.
His biological study spans a wide range of topics, including Tumor necrosis factor alpha, Endocrinology, Coagulation and Cell biology.
His Thrombin research includes themes of Molecular biology, Fibrin, Binding site and Tissue factor.
His research on Thrombomodulin also deals with topics like
- Receptor most often made with reference to Endothelial protein C receptor,
- Endothelium, which have a strong connection to Cancer research.
His Biochemistry study combines topics from a wide range of disciplines, such as Platelet activation and Thrombin receptor.
His study focuses on the intersection of Immunology and fields such as Protein S with connections in the field of Blood proteins.
His most cited work include:
- Extracellular histones are major mediators of death in sepsis (956 citations)
- Extracellular histones are major mediators of death in sepsis (956 citations)
- The roles of protein C and thrombomodulin in the regulation of blood coagulation. (938 citations)
What are the main themes of his work throughout his whole career to date?
Charles T. Esmon mostly deals with Protein C, Thrombin, Thrombomodulin, Immunology and Biochemistry.
Charles T. Esmon has researched Protein C in several fields, including Molecular biology, Receptor, Endothelial protein C receptor and Cell biology.
His work carried out in the field of Thrombin brings together such families of science as Endocrinology, Antithrombin, Binding site and Tissue factor.
Blood proteins is closely connected to Protein S in his research, which is encompassed under the umbrella topic of Thrombomodulin.
His study looks at the intersection of Immunology and topics like Pharmacology with Anticoagulant.
His study in Biochemistry is interdisciplinary in nature, drawing from both Biophysics and Prothrombinase.
He most often published in these fields:
- Protein C (75.88%)
- Thrombin (47.84%)
- Thrombomodulin (43.14%)
What were the highlights of his more recent work (between 2012-2021)?
- Immunology (36.47%)
- Protein C (75.88%)
- Inflammation (23.33%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Immunology, Protein C, Inflammation, Cell biology and Endothelial protein C receptor.
He interconnects Cancer research and Internal medicine, Endogeny, Coagulation in the investigation of issues within Immunology.
His Protein C research is multidisciplinary, incorporating elements of Receptor, Thrombomodulin, Thrombin and Pharmacology.
His work focuses on many connections between Thrombomodulin and other disciplines, such as Fusion protein, that overlap with his field of interest in Tumor necrosis factor alpha.
Charles T. Esmon combines subjects such as Reperfusion injury, Extracellular and Sepsis with his study of Inflammation.
His Cell biology research is multidisciplinary, relying on both Endothelial stem cell, Molecular biology and Innate immune system.
Between 2012 and 2021, his most popular works were:
- A randomized, double-blind, placebo-controlled, Phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation (210 citations)
- Platelets and neutrophil extracellular traps collaborate to promote intravascular coagulation during sepsis in mice. (208 citations)
- Loss of endothelial protein C receptors links coagulation and inflammation to parasite sequestration in cerebral malaria in African children. (145 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Internal medicine
The scientist’s investigation covers issues in Immunology, Inflammation, Protein C, Cell biology and Thrombomodulin.
The study incorporates disciplines such as Necrosis and Cancer research in addition to Immunology.
In Inflammation, he works on issues like Extracellular, which are connected to Histone.
The Protein C study combines topics in areas such as Endothelial stem cell, Molecular biology, Endothelial protein C receptor, Thrombin and In vivo.
His Thrombin study integrates concerns from other disciplines, such as Receptor, Coagulation and Pharmacology.
His studies deal with areas such as Randomized controlled trial and Fibrin as well as Thrombomodulin.
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