World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
138
Citations
65488
World Ranking
307
National Ranking
206

Medicine

D-Index
137
Citations
65342
World Ranking
1914
National Ranking
1087

Research.com Recognitions

  • 2014 - Distinguished Scientist Award, American Heart Association
  • 2013 - Robert J. and Claire Pasarow Foundation Medical Research Award
  • 2002 - Member of the National Academy of Sciences

Overview

Charles T. Esmon is affiliated with the Oklahoma Medical Research Foundation in the United States. Their research primarily focuses on medicine with a significant emphasis on hematology, genetics, immunology, molecular biology, and epidemiology.

They have contributed extensively to several main topics in biomedical research, including:

  • Blood Coagulation and Thrombosis Mechanisms
  • Hemophilia Treatment and Research
  • Platelet Disorders and Treatments
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Phagocytosis and Immune Regulation
  • Systemic Lupus Erythematosus Research
  • Mesenchymal Stem Cell Research

Their recent works include papers published in notable journals such as Science, Cell Metabolism, Circulation Research, and Blood. Some of their recent publications are:

  • Lipid presentation by the protein C receptor links coagulation with autoimmunity, 2021, Science
  • Aging Reprograms the Hematopoietic-Vascular Niche to Impede Regeneration and Promote Fibrosis, 2020, Cell Metabolism
  • Different DOACs Control Inflammation in Cardiac Ischemia-Reperfusion Differently, 2020, Circulation Research
  • Factor VIIa induces extracellular vesicles from the endothelium: a potential mechanism for its hemostatic effect, 2021, Blood
  • Activated protein C has a regulatory role in factor VIII function, 2021, Blood

Frequent co-authors of Charles T. Esmon include:

  • Usha R. Pendurthi
  • Shiva Keshava
  • L. Vijaya Mohan Rao
  • John H. Griffin
  • Vijay Kondreddy

The scientist's work frequently appears in the journals Blood, UNC Libraries, Circulation Research, Blood Advances, and Science, with the highest number of publications in Blood.

Over the course of their career, Charles T. Esmon has received several awards, including:

  • Distinguished Scientist Award, American Heart Association, 2014
  • Robert J. and Claire Pasarow Foundation Medical Research Award, 2013
  • Member of the National Academy of Sciences, 2002

Best Publications

  • Extracellular histones are major mediators of death in sepsis

    Jun Xu;Xiaomei Zhang;Rosana Pelayo;Marc Monestier

  • The roles of protein C and thrombomodulin in the regulation of blood coagulation.

    Charles T. Esmon

  • Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon.

    F B Taylor;A Chang;C T Esmon;A D'Angelo

  • The Protein C Pathway

    Charles T. Esmon

  • The interactions between inflammation and coagulation

    Charles T. Esmon

  • Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C

    Charles T. Esmon;Whyte G. Owen

  • Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C.

    N L Esmon;W G Owen;C T Esmon

  • The regulation of natural anticoagulant pathways

    Charles T. Esmon

  • Dysfunction of Endothelial Protein C Activation in Severe Meningococcal Sepsis

    Saul N. Faust;Michael Levin;Odile B. Harrison;Robert D. Goldin

  • FAMILIAL PROTEIN S DEFICIENCY IS ASSOCIATED WITH RECURRENT THROMBOSIS

    R R Nixon;M R Cooper;C T Esmon

  • Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4

    Fabrizio Semeraro;Concetta T. Ammollo;James H. Morrissey;George L. Dale

  • Assembly of the platelet prothrombinase complex is linked to vesiculation of the platelet plasma membrane. Studies in Scott syndrome: an isolated defect in platelet procoagulant activity.

    P J Sims;T Wiedmer;C T Esmon;H J Weiss

  • Interleukin 1 induces endothelial cell procoagulant while suppressing cell-surface anticoagulant activity

    Peter P. Nawroth;Dean A. Handley;Charles T. Esmon;David M. Stern

  • The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex.

    Deborah J. Stearns-Kurosawa;Shinichiro Kurosawa;Jeffery S. Mollica;Gary L. Ferrell

  • Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor.

    K Fukudome;C T Esmon

  • Future research directions in acute lung injury: Summary of a National Heart, Lung, and Blood Institute Working Group

    Michael A. Matthay;Guy A. Zimmerman;Charles Esmon;Jahar Bhattacharya

  • Extracellular Histones Are Mediators of Death through TLR2 and TLR4 in Mouse Fatal Liver Injury

    Jun Xu;Xiaomei Zhang;Marc Monestier;Naomi L. Esmon

  • Recurrent venous thromboembolism in patients with a partial deficiency of protein S.

    Charles T. Esmon

  • The inhibition of blood coagulation by activated protein C through the selective inactivation of activated factor V

    Frederick J. Walker;Paul W. Sexton;Charles T. Esmon

  • Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro.

    K L Moore;S P Andreoli;N L Esmon;C T Esmon

Frequent Co-Authors

Naomi L. Esmon
Naomi L. Esmon Oklahoma Medical Research Foundation
Alireza R. Rezaie
Alireza R. Rezaie Oklahoma Medical Research Foundation
Fletcher B. Taylor
Fletcher B. Taylor Oklahoma Medical Research Foundation
Wolfram Ruf
Wolfram Ruf Johannes Gutenberg University of Mainz
James H. Morrissey
James H. Morrissey University of Michigan–Ann Arbor
Peter P. Nawroth
Peter P. Nawroth Heidelberg University
Arthur E. Johnson
Arthur E. Johnson Texas A&M University
Orit Kollet
Orit Kollet Weizmann Institute of Science
Tsvee Lapidot
Tsvee Lapidot Weizmann Institute of Science
Vladimir R. Muzykantov
Vladimir R. Muzykantov University of Pennsylvania

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