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Biology and Biochemistry

D-Index
66
Citations
15565
World Ranking
8671
National Ranking
3891

Overview

José A. Fernández is affiliated with the Scripps Research Institute in the United States. Their research is primarily concentrated in the field of Medicine, with a significant focus on several subfields including Hematology, Molecular Biology, Ophthalmology, Neurology, and Critical Care and Intensive Care Medicine.

The scientist's work covers a range of topics, notably Blood Coagulation and Thrombosis Mechanisms, Retinal Diseases and Treatments, Retinal and Optic Conditions, Neuroinflammation and Neurodegeneration Mechanisms, Vitamin C and Antioxidants Research, Protease and Inhibitor Mechanisms, and Extracellular Vesicles in Disease.

Their recent scientific publications include:

  • Activated Protein C Attenuates Experimental Autoimmune Encephalomyelitis Progression by Enhancing Vascular Integrity and Suppressing Microglial Activation, 2020, Frontiers in Neuroscience
  • Platelet protein S limits venous but not arterial thrombosis propensity by controlling coagulation in the thrombus, 2020, Blood
  • Protection of ischemic white matter and oligodendrocytes in mice by 3K3A-activated protein C, 2021, The Journal of Experimental Medicine
  • 3K3A-Activated Protein C Protects the Blood-Brain Barrier and Neurons From Accelerated Ischemic Injury Caused by Pericyte Deficiency in Mice, 2022, Frontiers in Neuroscience
  • Activated protein C and PAR1-derived and PAR3-derived peptides are anti-inflammatory by suppressing macrophage NLRP3 inflammasomes, 2020, Journal of Thrombosis and Haemostasis

José A. Fernández frequently publishes in academic journals such as:

  • Blood
  • Journal of Thrombosis and Haemostasis
  • Research and Practice in Thrombosis and Haemostasis
  • Frontiers in Neuroscience
  • International Journal of Molecular Sciences

The scientist collaborates extensively with other researchers. Some of the most frequent co-authors include John H. Griffin, Laurent O. Mosnier, Berislav V. Zloković, Marjan Boerma, and Sunil Bansal.

Best Publications

  • Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective.

    Tong Cheng;Dong Liu;John H. Griffin;José A. Fernández

  • Anticoagulant protein C pathway defective in majority of thrombophilic patients [see comments]

    JH Griffin;B Evatt;C Wideman;JA Fernandez

  • Anticoagulant protein C pathway defective in majority of thrombophilic patients.

    John H. Griffin;Bruce Evatt;Bruce Evatt;Carol Wideman;Carol Wideman;Jose A. Fernandez;Jose A. Fernandez

  • Ion Exchangers NHX1 and NHX2 Mediate Active Potassium Uptake into Vacuoles to Regulate Cell Turgor and Stomatal Function in Arabidopsis

    Verónica Barragán;Eduardo O. Leidi;Zaida Andrés;Lourdes Rubio

  • Activated protein C resistance caused by Arg506Gln mutation in factor Va

    JudithS. Greengard;Xi Sun;Xiao Xu;JoseA. Fernandez

  • Endotoxemia and sepsis mortality reduction by non-anticoagulant–activated protein C

    Edward J. Kerschen;José A. Fernandez;Brian C. Cooley;Xia V. Yang

  • The AtNHX1 exchanger mediates potassium compartmentation in vacuoles of transgenic tomato.

    Eduardo O. Leidi;Verónica Barragán;Lourdes Rubio;Abdelaziz El-Hamdaoui

  • Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3.

    Huang Guo;Dong Liu;Harris Gelbard;Tong Cheng

  • Expression of the α-thionin gene from barley in tobacco confers enhanced resistance to bacterial pathogens

    Maria José Carmona;Antonio Molina;José Antonio Fernández;Juan José López-Fando

  • Acute colorectal obstruction: treatment with self-expandable metallic stents before scheduled surgery--results of a multicenter study.

    Mainar A;De Gregorio Ariza Ma;Tejero E;Tobío R

  • Activated protein C.

    J. H. Griffin;J. A. Fernández;A. J. Gale;L. O. Mosnier

  • Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage.

    Tong Cheng;Anthony L Petraglia;Zhang Li;Meenakshisundaram Thiyagarajan

  • Prognostic value of protein C concentrations in neutropenic patients at high risk of severe septic complications.

    Rolf M. Mesters;Jeff Helterbrand;Barbara G. Utterback;S. Betty Yan

  • High-density lipoprotein enhancement of anticoagulant activities of plasma protein S and activated protein C

    John H. Griffin;Kazuhisa Kojima;Carole L. Banka;Linda K. Curtiss

  • Anti-Inflammatory, Antithrombotic, and Neuroprotective Effects of Activated Protein C in a Murine Model of Focal Ischemic Stroke

    Masayoshi Shibata;S. Ram Kumar;Arun Amar;Jose A. Fernandez

  • Protein S binds to and inhibits factor Xa

    Mary J. Heeb;Jan Rosing;Harry M. Bakker;Jose A. Fernandez

  • Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C.

    Dong Liu;Tong Cheng;Huang Guo;José A Fernández

  • Acute colorectal obstruction: stent placement for palliative treatment--results of a multicenter study.

    M A de Gregorio;A Mainar;E Tejero;R Tobío

  • Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells

    Zhihui Zhong;Hristelina Ilieva;Lee Hallagan;Robert Bell

  • Trimethylene Oxide. I. Microwave Spectrum, Dipole Moment, and Double Minimum Vibration

    Sunney I. Chan;John Zinn;Jose Fernandez;William D. Gwinn

Frequent Co-Authors

John H. Griffin
John H. Griffin Scripps Research Institute
Berislav V. Zlokovic
Berislav V. Zlokovic University of Southern California
Tilman M. Hackeng
Tilman M. Hackeng Maastricht University
Francis J. Castellino
Francis J. Castellino University of Notre Dame
Owen J. T. McCarty
Owen J. T. McCarty Oregon Health & Science University
Philip E. Dawson
Philip E. Dawson Scripps Research Institute
Miguel A. Botella
Miguel A. Botella University of Malaga
Wolfram Ruf
Wolfram Ruf Johannes Gutenberg University of Mainz
Bruno O. Villoutreix
Bruno O. Villoutreix Université Paris Cité
Félix L. Figueroa
Félix L. Figueroa University of Malaga

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