What is he best known for?
The fields of study he is best known for:
- Enzyme
- Gene
- Internal medicine
His scientific interests lie mostly in Protein C, Biochemistry, Internal medicine, Immunology and Thrombin.
John H. Griffin mostly deals with Protein S in his studies of Protein C.
His Biochemistry research focuses on Factor XII and how it relates to Kinin.
John H. Griffin combines subjects such as Gastroenterology and Endocrinology with his study of Internal medicine.
His Immunology research integrates issues from Blood proteins, Cancer research, Protein C deficiency and Antithrombotic.
The study incorporates disciplines such as Fibrin, Clotting factor, Factor V and Carboxypeptidase in addition to Thrombin.
His most cited work include:
- Deficiency of protein C in congenital thrombotic disease. (1075 citations)
- The cytoprotective protein C pathway. (618 citations)
- Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective. (512 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Protein C, Biochemistry, Internal medicine, Thrombin and Molecular biology.
He studies Protein S, a branch of Protein C.
The Internal medicine study combines topics in areas such as Gastroenterology, Endocrinology and Cardiology.
His study looks at the relationship between Thrombin and fields such as Cell biology, as well as how they intersect with chemical problems.
John H. Griffin focuses mostly in the field of Molecular biology, narrowing it down to matters related to Protein A/G and, in some cases, Protein G.
His research in Immunology intersects with topics in Receptor, Cancer research and Antithrombotic.
He most often published in these fields:
- Protein C (53.50%)
- Biochemistry (30.33%)
- Internal medicine (25.82%)
What were the highlights of his more recent work (between 2011-2021)?
- Protein C (53.50%)
- Thrombin (24.88%)
- Pharmacology (14.46%)
In recent papers he was focusing on the following fields of study:
His main research concerns Protein C, Thrombin, Pharmacology, Immunology and Biochemistry.
The various areas that John H. Griffin examines in his Protein C study include Cell signaling, Neuroprotection, Receptor, Molecular biology and In vivo.
His Thrombin research is multidisciplinary, incorporating perspectives in Hemostasis, Coagulation, Skeletal muscle and Myosin.
His Pharmacology study incorporates themes from Anticoagulant and Recombinant DNA.
His Immunology research includes themes of Venous thrombosis and Downregulation and upregulation.
His Internal medicine study combines topics in areas such as Gastroenterology and Cardiology.
Between 2011 and 2021, his most popular works were:
- Biased agonism of protease-activated receptor 1 by activated protein C caused by noncanonical cleavage at Arg46. (150 citations)
- Activated protein C: biased for translation (143 citations)
- Activated protein C: biased for translation (143 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Gene
- Internal medicine
John H. Griffin mainly focuses on Protein C, Neuroprotection, Receptor, Pharmacology and Immunology.
He specializes in Protein C, namely Protein S.
His Neuroprotection study integrates concerns from other disciplines, such as Serine protease, Protease, Stroke, Fibrinolytic agent and Neurogenesis.
John H. Griffin has researched Receptor in several fields, including Molecular biology, Cell signaling and Protease-Activated Receptor 1.
In his research, Genetic screen is intimately related to Toxicity, which falls under the overarching field of Pharmacology.
John H. Griffin interconnects Cancer research and Recombinant DNA in the investigation of issues within Immunology.
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