World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
77
Citations
17441
World Ranking
4873
National Ranking
2337

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Alvin H. Schmaier is affiliated with University Hospitals of Cleveland in the United States. Their research primarily concentrates in the field of medicine, with a specific focus on hematology, genetics, pulmonary and respiratory medicine, oncology, and immunology.

The scientist has contributed extensively to topics such as coagulation, bradykinin, polyphosphates, and angioedema; blood coagulation and thrombosis mechanisms; inflammatory biomarkers in disease prognosis; platelet disorders and treatments; complement system involvement in diseases; COVID-19 clinical research studies; and hemophilia treatment and research.

Several recent publications highlight their work, including:

  • "SARS-CoV-2 and ACE2: The biology and clinical data settling the ARB and ACEI controversy" (2020, EBioMedicine)
  • "Final Study Report of Andexanet Alfa for Major Bleeding With Factor Xa Inhibitors" (2023, Circulation)
  • "Elevated neutrophil-lymphocyte ratio predicts mortality following elective endovascular aneurysm repair" (2020, Journal of Vascular Surgery)
  • "A targetable pathway in neutrophils mitigates both arterial and venous thrombosis" (2022, Science Translational Medicine)
  • "Ponatinib and other CML Tyrosine Kinase Inhibitors in Thrombosis" (2020, International Journal of Molecular Sciences)

Frequent co-authors in their research include:

  • Keith R. McCrae
  • Alona Merkulova
  • Alessandro S. Pinheiro
  • Ana Acácia S. Pinheiro
  • Karem C. Harth

Their publications frequently appear in notable venues such as:

  • Blood
  • Research and Practice in Thrombosis and Haemostasis
  • Journal of Thrombosis and Haemostasis
  • Blood Advances
  • Journal of the American College of Surgeons

Alvin H. Schmaier is recognized as a member of the Association of American Physicians.

Best Publications

  • Contact system: a vascular biology modulator with anticoagulant, profibrinolytic, antiadhesive, and proinflammatory attributes

    Robert W. Colman;Alvin H. Schmaier

  • Recommendations for the standardization of light transmission aggregometry : a consensus of the working party from the platelet physiology subcommittee of SSC/ISTH

    M. Cattaneo;C. Cerletti;P. Harrison;C. P M Hayward

  • Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products.

    Masayuki Wada;Cynthia J. DeLong;Yu H. Hong;Caroline J. Rieke

  • In vivo roles of factor XII.

    Thomas Renné;Alvin H. Schmaier;Katrin F. Nickel;Margareta Blombäck

  • Protease nexin-II (amyloid beta-protein precursor): a platelet alpha-granule protein.

    WE Van Nostrand;AH Schmaier;JS Farrow;DD Cunningham

  • The contact activation and kallikrein/kinin systems: pathophysiologic and physiologic activities.

    Alvin H. Schmaier

  • Identification and characterization of prolylcarboxypeptidase as an endothelial cell prekallikrein activator.

    Zia Shariat-Madar;Fakhri Mahdi;Alvin H. Schmaier

  • Use of factor IX complex in warfarin-related intracranial hemorrhage.

    Nicholas M. Boulis;Miroslav P. Bobek;Alvin Schmaier;Julian T. Hoff

  • Platelet aggregation testing in platelet-rich plasma: description of procedures with the aim to develop standards in the field.

    Lan Zhou;Alvin H. Schmaier

  • Thrombosis in patients with connective tissue diseases treated with specific cyclooxygenase 2 inhibitors: A report of four cases

    Leslie J. Crofford;Jim C. Oates;W. Joseph McCune;Samardeep Gupta

  • Prekallikrein Activation and High-Molecular-Weight Kininogen Consumption in Hereditary Angioedema

    Marc Schapira;Lee D. Silver;Cheryl F. Scott;Alvin H. Schmaier

  • Endothelial Kruppel-like factor 4 protects against atherothrombosis in mice

    Guangjin Zhou;Anne Hamik;Lalitha Nayak;Hongmei Tian

  • The kallikrein-kinin and the renin-angiotensin systems have a multilayered interaction.

    Alvin H Schmaier

  • High molecular weight kininogen regulates prekallikrein assembly and activation on endothelial cells: A novel mechanism for contact activation

    Guacyara Motta;Guacyara Motta;Guacyara Motta;Rasmus Rojkjaer;Rasmus Rojkjaer;Rasmus Rojkjaer;Ahmed A.K. Hasan;Ahmed A.K. Hasan;Ahmed A.K. Hasan;Douglas B. Cines;Douglas B. Cines;Douglas B. Cines

  • The expression of high molecular weight kininogen on human umbilical vein endothelial cells.

    Alvin H Schmaier;A. Kuo;D. Lundberg;S. Murray

  • Anti-C5a Ameliorates Coagulation/Fibrinolytic Protein Changes in a Rat Model of Sepsis

    Ines J. Laudes;Jeffrey C. Chu;Sujata Sikranth;Markus Huber-Lang

  • The plasma kallikrein–kinin system: its evolution from contact activation

    Alvin H. Schmaier;K. R. McCrae

  • Identification of cytokeratin 1 as a binding protein and presentation receptor for kininogens on endothelial cells

    Ahmed A. K. Hasan;Timothy Zisman;Alvin H. Schmaier

  • Platelet Aggregation Testing in Platelet-Rich Plasma

    Lan Zhou;Alvin H. Schmaier

  • Enzymes and Receptors of Prostaglandin Pathways with Arachidonic Acid-derived Versus Eicosapentaenoic

    Masayuki Wada;Cynthia J. DeLong;Yu H. Hong;Caroline J. Rieke

Frequent Co-Authors

Robert W. Colman
Robert W. Colman Temple University
Douglas B. Cines
Douglas B. Cines University of Pennsylvania
Mukesh K. Jain
Mukesh K. Jain Brown University
Daniel I. Simon
Daniel I. Simon Case Western Reserve University
Henry I. Mosberg
Henry I. Mosberg University of Michigan–Ann Arbor
Benedict R. Lucchesi
Benedict R. Lucchesi University of Michigan–Ann Arbor
Hillard M. Lazarus
Hillard M. Lazarus Case Western Reserve University
Stefan Niewiarowski
Stefan Niewiarowski Temple University
James H. Morrissey
James H. Morrissey University of Michigan–Ann Arbor
Heiko Herwald
Heiko Herwald Lund University

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