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Biology and Biochemistry

D-Index
60
Citations
12624
World Ranking
11975
National Ranking
5141

Overview

Ellinor I.B. Peerschke is affiliated with Memorial Sloan Kettering Cancer Center in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a notable focus on Immunology, Molecular Biology, Oncology, Pulmonary and Respiratory Medicine, and Infectious Diseases.

The scientist's work concentrates on several main topics, including:

  • Venous Thromboembolism Diagnosis and Management
  • Acute Ischemic Stroke Management
  • Cerebrovascular and Carotid Artery Diseases
  • COVID-19 Clinical Research Studies
  • Complement system in diseases
  • CAR-T cell therapy research
  • SARS-CoV-2 and COVID-19 Research

Frequent co-authors in Peerschke's publications include Berhane Ghebrehiwet, Anne G. Savitt, Babak B. Navi, Carla Sherman, and Richard Genova, reflecting collaboration patterns in their research projects.

Peerschke has published multiple papers in journals such as Frontiers in Immunology, Nature, Frontiers in Oncology, Annals of Neurology, and Cellular and Molecular Gastroenterology and Hepatology. The publication venues with the highest counts are Frontiers in Immunology and Nature.

Some notable recent publications by Ellinor I.B. Peerschke include:

  • "Senolytic CAR T cells reverse senescence-associated pathologies," 2020, Nature
  • "Mechanisms of Ischemic Stroke in Patients with Cancer: A Prospective Study," 2021, Annals of Neurology
  • "SARS-CoV-2 Exacerbates COVID-19 Pathology Through Activation of the Complement and Kinin Systems," 2021, Frontiers in Immunology
  • "Loss of Mucosal p32/gC1qR/HABP1 Triggers Energy Deficiency and Impairs Goblet Cell Differentiation in Ulcerative Colitis," 2021, Cellular and Molecular Gastroenterology and Hepatology
  • "Complement and coagulation: key triggers of COVID-19-induced multiorgan pathology," 2020, Journal of Clinical Investigation

Best Publications

  • A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa.

    Barry S. Coller;Ellinor I. Peerschke;Lesley E. Scudder;Carole A. Sullivan

  • Senolytic CAR T cells reverse senescence-associated pathologies.

    Corina Amor;Judith Feucht;Josef Leibold;Yu-Jui Ho

  • Guideline for Reversal of Antithrombotics in Intracranial Hemorrhage: A Statement for Healthcare Professionals from the Neurocritical Care Society and Society of Critical Care Medicine.

    Jennifer A. Frontera;John J. Lewin;Alejandro A. Rabinstein;Imo P. Aisiku

  • Studies with a murine monoclonal antibody that abolishes ristocetin- induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor

    Barry S. Coller;Ellinor I. Peerschke;Lesley E. Scudder;Carole A. Sullivan

  • Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1q.

    B Ghebrehiwet;B L Lim;E I Peerschke;A C Willis

  • Complement activation on platelets: implications for vascular inflammation and thrombosis.

    Ellinor I. Peerschke;Wei Yin;Berhane Ghebrehiwet

  • Rituximab in the treatment of acquired factor VIII inhibitors

    Adrian Wiestner;Hearn J. Cho;Adam S. Asch;Mary Ann Michelis

  • Identification of the zinc-dependent endothelial cell binding protein for high molecular weight kininogen and factor XII: identity with the receptor that binds to the globular "heads" of C1q (gC1q-R).

    Kusumam Joseph;Berhane Ghebrehiwet;Ellinor I. B. Peerschke;Kenneth B. M. Reid

  • Staphylococcus aureus Protein A Recognizes Platelet gC1qR/p33: a Novel Mechanism for Staphylococcal Interactions with Platelets

    Truc Nguyen;Berhane Ghebrehiwet;Ellinor I. B. Peerschke

  • gC1q-R/p33, a member of a new class of multifunctional and multicompartmental cellular proteins, is involved in inflammation and infection.

    Berhane Ghebrehiwet;Boon-Leong Lim;Rajeev Kumar;Xiaodong Feng

  • cC1q-R (calreticulin) and gC1q-R/p33: ubiquitously expressed multi-ligand binding cellular proteins involved in inflammation and infection

    Berhane Ghebrehiwet;Ellinor I.B Peerschke

  • Blood platelets activate the classical pathway of human complement

    E. I. B. Peerschke;W. Yin;S. E. Grigg;B. Ghebrehiwet

  • Platelet activation by C1q results in the induction of alpha IIb/beta 3 integrins (GPIIb-IIIa) and the expression of P-selectin and procoagulant activity.

    Ellinor I. B. Peerschke;Kenneth B. M. Reid;Berhane Ghebrehiwet

  • Curriculum content and evaluation of resident competency in clinical pathology (laboratory medicine): a proposal

    Brian R. Smith;Alan Wells;C. Bruce Alexander;Edwin Bovill

  • Human T cells express specific binding sites for C1q. Role in T cell activation and proliferation.

    A. Chen;S. Gaddipati;Yuqun Hong;D. J. Volkman

  • The binding protein for globular heads of complement C1q, gC1qR. Functional expression and characterization as a novel vitronectin binding factor.

    Boon-Leong Lim;Kenneth B.M. Reid;Berhane Ghebrehiwet;Ellinor I.B. Peerschke

  • Complement activation on platelets correlates with a decrease in circulating immature platelets in patients with immune thrombocytopenic purpura.

    Ellinor I. B. Peerschke;Biree Andemariam;Wei Yin;James B. Bussel

  • Guideline for Reversal of Antithrombotics in Intracranial Hemorrhage: Executive Summary. A Statement for Healthcare Professionals From the Neurocritical Care Society and the Society of Critical Care Medicine

    Jennifer A. Frontera;John J. Lewin;Alejandro A. Rabinstein;Imo P. Aisiku

  • Novel pathogenic mechanism and therapeutic approaches to angioedema associated with C1 inhibitor deficiency

    Fleur Bossi;Fabio Fischetti;Domenico Regoli;Paolo Durigutto

  • The C1q family of proteins: insights into the emerging non-traditional functions.

    Berhane Ghebrehiwet;Kinga K. Hosszu;Alisa Valentino;Ellinor I. B. Peerschke

Frequent Co-Authors

Berhane Ghebrehiwet
Berhane Ghebrehiwet Stony Brook University
Babette B. Weksler
Babette B. Weksler Cornell University
Uday Kishore
Uday Kishore Brunel University London
Richard T. Silver
Richard T. Silver Cornell University
Naphtali Savion
Naphtali Savion Tel Aviv University
Zoltán Prohászka
Zoltán Prohászka Semmelweis University
Allen P. Kaplan
Allen P. Kaplan Medical University of South Carolina
James B. Bussel
James B. Bussel Cornell University
Kenneth B. M. Reid
Kenneth B. M. Reid University of Oxford
George Füst
George Füst Semmelweis University

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