World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
138
Citations
60247
World Ranking
309
National Ranking
208

Overview

Edward F. Plow is affiliated with the Cleveland Clinic Lerner College of Medicine in the United States and has a substantial body of research primarily in the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their work spans 38 publications in biochemistry-related disciplines and 36 in medical research.

The scientist's research focuses on several main topics including Cell Adhesion Molecules, Caveolin-1 and its role in cellular processes, Hippo pathway signaling involving YAP/TAZ, protease and inhibitor mechanisms, renal diseases and glomerulopathies, cellular mechanics and interactions, and the study of angiogenesis and VEGF in cancer.

Their research output includes notable recent papers such as:

  • Mechanism of integrin activation by talin and its cooperation with kindlin, 2022, Nature Communications
  • Integrin mediates cell entry of the SARS-CoV-2 virus independent of cellular receptor ACE2, 2022, Journal of Biological Chemistry
  • Effects of thrombospondin-4 on pro-inflammatory phenotype differentiation and apoptosis in macrophages, 2020, Cell Death and Disease
  • Initiation of focal adhesion assembly by talin and kindlin: A dynamic view, 2020, Protein Science
  • Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment, 2020, Developmental Cell

Frequent coauthors collaborating with Edward F. Plow include:

  • Elżbieta Pluskota (12 joint publications)
  • Katarzyna Białkowska (10 joint publications)
  • Jun Qin (9 joint publications)
  • Lucia R. Languino (7 joint publications)
  • Dario C. Altieri (7 joint publications)

The scientist regularly publishes in venues such as:

  • Journal of Biological Chemistry (2 publications)
  • Blood (2 publications)
  • Scientific Reports (2 publications)
  • Journal of Thrombosis and Haemostasis (2 publications)
  • The FASEB Journal (2 publications)

Within the subfields of study, their work predominantly addresses Molecular Biology (17 publications), Immunology and Allergy (15 publications), Cell Biology (13 publications), Cancer Research (7 publications), and Hematology (4 publications).

Best Publications

  • Ligand binding to integrins.

    Edward F. Plow;Thomas A. Haas;Li Zhang;Joseph Loftus

  • Platelet membrane glycoprotein IIb/IIIa: member of a family of Arg-Gly-Asp--specific adhesion receptors

    Robert Pytela;Michael D. Pierschbacher;Mark H. Ginsberg;Edward F. Plow

  • Platelet glycoprotein IIb/IIIa receptors in cardiovascular medicine.

    Jeffrey Lefkovits;Edward F. Plow;Eric J. Topol

  • Human platelets possess an inducible and saturable receptor specific for fibrinogen

    G. A. Marguerie;Edward F Plow;T. S. Edgington

  • A potential basis for the thrombotic risks associated with lipoprotein(a).

    Lindsey A. Miles;Gunther M. Fless;Eugene G. Levin;Angelo M. Scanu

  • The effect of Arg-Gly-Asp-containing peptides on fibrinogen and von Willebrand factor binding to platelets.

    Edward F. Plow;Michael D. Pierschbacher;Erkki Ruoslahti;Gerard A. Marguerie

  • Role of cell-surface lysines in plasminogen binding to cells: identification of alpha-enolase as a candidate plasminogen receptor.

    Lindsey A. Miles;Carol M. Dahlberg;Janet Plescia;Jordi Felez

  • Arginyl-glycyl-aspartic acid (RGD): a cell adhesion motif.

    Stanley E. D'Souza;Mark H. Ginsberg;Edward F. Plow

  • Platelet GPIIb-IIIa blockers

    Eric J Topol;Tatiana V Byzova;Edward F Plow

  • A Structural Mechanism of Integrin αIIbβ3 “Inside-Out” Activation as Regulated by Its Cytoplasmic Face

    Olga Vinogradova;Algirdas Velyvis;Asta Velyviene;Bin Hu

  • Inside-out integrin signalling

    Mark H. Ginsberg;Xiaoping Du;Edward F. Plow

  • A Mechanism for Modulation of Cellular Responses to VEGF: Activation of the Integrins

    Tatiana V. Byzova;Corey K. Goldman;Nisar Pampori;Kenneth A. Thomas

  • Ligands “activate” integrin αIIbβ3 (platelet GPIIb-IIIa)

    Xiaoping Du;Edward F. Plow;Andrew L. Frelinger;Timothy E. O'Toole

  • The cell biology of the plasminogen system.

    Edward F. Plow;Thomas Herren;Alexander Redlitz;Lindsey A. Miles

  • Cell adhesion molecules in coronary artery disease

    Yangsoo Jang;A.Michael Lincoff;Edward F. Plow;Eric J. Topol

  • Leukocyte engagement of fibrin(ogen) via the integrin receptor αMβ2/Mac-1 is critical for host inflammatory response in vivo

    Matthew J. Flick;Xin Li Du;David P. Witte;Markéta Jiroušková

  • Localization of an Arg-Gly-Asp recognition site within an integrin adhesion receptor.

    Stanley E. D'Souza;Mark H. Ginsberg;Timothy A. Burke;Stephen C. T. Lam

  • A beta 3 integrin mutation abolishes ligand binding and alters divalent cation-dependent conformation.

    Joseph C. Loftus;Timothy E. O'Toole;Edward F. Plow;Alison Glass

  • Effects of Disruption of The Plasminogen Gene on Thrombosis, Growth, and Health in Mice

    V A Ploplis;Peter Carmeliet;S Vazirzadeh;I Van Vlaenderen

  • Interaction of fibrinogen with its platelet receptor as part of a multistep reaction in ADP-induced platelet aggregation.

    G. A. Marguerie;T. S. Edgington;Edward F Plow

Frequent Co-Authors

Mark H. Ginsberg
Mark H. Ginsberg University of California, San Diego
Jun Qin
Jun Qin Cleveland Clinic Lerner College of Medicine
Thomas S. Edgington
Thomas S. Edgington Scripps Research Institute
Tatiana V. Byzova
Tatiana V. Byzova Cleveland Clinic Lerner College of Medicine
Lindsey A. Miles
Lindsey A. Miles Scripps Research Institute
Eric J. Topol
Eric J. Topol Scripps Research Institute
Lucia R. Languino
Lucia R. Languino Thomas Jefferson University
Dario C. Altieri
Dario C. Altieri The Wistar Institute
William P. Schiemann
William P. Schiemann Case Western Reserve University
Paul L. Fox
Paul L. Fox Cleveland Clinic Lerner College of Medicine

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