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Genetics

D-Index
69
Citations
18740
World Ranking
2341
National Ranking
28

Overview

Rolf Ohlsson is affiliated with the Karolinska Institute in Sweden and conducts research primarily in the field of Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology.

Their work addresses several main topics which include:

  • Genomics and Chromatin Dynamics
  • RNA Research and Splicing
  • Single-cell and Spatial Transcriptomics

Ohlsson has contributed to multiple research articles published in notable venues such as Nature Genetics and Nucleic Acids Research. Some of their recent papers include:

  • "Author Correction: WNT signaling and AHCTF1 promote oncogenic MYC expression through super-enhancer-mediated gene gating," published in 2020 in Nature Genetics
  • "MYC as a driver of stochastic chromatin networks: implications for the fitness of cancer cells," published in 2020 in Nucleic Acids Research

The researcher commonly collaborates with several co-authors, including:

  • Barbara A. Scholz
  • Noriyuki Sumida
  • Emmanouil G. Sifakis
  • Anita Göndör
  • Carolina Diettrich Mallet de Lima

Ohlsson's research contributions are concentrated on understanding complex genetic and molecular mechanisms, particularly those involving chromatin structure and gene regulation at the single-cell level.

Best Publications

  • The epigenetic progenitor origin of human cancer

    Andrew P. Feinberg;Rolf Ohlsson;Steven Henikoff

  • Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra-and interchromosomal interactions

    Zhihu Zhao;Gholamreza Tavoosidana;Mikael Sjölinder;Anita Göndör

  • Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

    Göran Bertilsson;Jessica Heidrich;Kristian Svensson;Michael Åsman

  • CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease

    Rolf Ohlsson;Rainer Renkawitz;Victor Lobanenkov

  • CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2

    Sreenivasulu Kurukuti;Vijay Kumar Tiwari;Gholamreza Tavoosidana;Elena Pugacheva

  • Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive

    Chandrasekhar Kanduri;Vinod Pant;Dmitri Loukinov;Elena Pugacheva

  • BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma

    Dmitri I. Loukinov;Elena Pugacheva;Sergei Vatolin;Svetlana D. Pack

  • Loss of Imprinting of Igf2 Alters Intestinal Maturation and Tumorigenesis in Mice

    Takashi Sakatani;Atsushi Kaneda;Christine A. Iacobuzio-Donahue;Mark G. Carter

  • Coexpression of the sis and myc proto-oncogenes in developing human placenta suggests autocrine control of trophoblast growth

    Anton Scott Goustin;Christer Betsholtz;Susan Pfeifer-Ohlsson;Håkan Persson

  • Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability.

    Hengmi Cui;Isabelle L. Horon;Rolf Ohlsson;Stanley R. Hamilton

  • The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer.

    Elena M Klenova;Herbert C Morse;Rolf Ohlsson;Victor V Lobanenkov

  • IGF2 is parentally imprinted during human embryogenesis and in the Beckwith–Wiedemann syndrome

    Rolf Ohlsson;Anders Nyström;Susan Pfeifer-Ohlsson;Virpi Töhönen

  • Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation

    Wenqiang Yu;Vasudeva Ginjala;Vinod Pant;Igor Chernukhin

  • FOXP3 promoter demethylation reveals the committed Treg population in humans.

    Peter C. J. Janson;Malin E. Winerdal;Per Marits;Magnus Thörn

  • CTCF is conserved from Drosophila to humans and confers enhancer blocking of the Fab-8 insulator

    Hanlim Moon;Galina Filippova;Dmitry Loukinov;Elena Pugacheva

  • DNA methylation and genomic imprinting: insights from cancer into epigenetic mechanisms

    Andrew P Feinberg;Hengmi Cui;Rolf Ohlsson

  • The nucleotides responsible for the direct physical contact between the chromatin insulator protein CTCF and the H19 imprinting control region manifest parent of origin-specific long-distance insulation and methylation-free domains

    Vinod Pant;Piero Mariano;Chandrasekhar Kanduri;Anita Mattsson

  • Spatial and temporal pattern of cellular myc oncogene expression in developing human placenta: Implications for embryonic cell proliferation

    Susan Pfeifer-Ohlsson;Anton Scott Goustin;Jan Rydnert;Torsten Wahlström

  • Angiogenesis during human extraembryonic development involves the spatiotemporal control of PDGF ligand and receptor gene expression.

    L. Holmgren;A. Glaser;S. Pfeifer-Ohlsson;R. Ohlsson

  • Mutation of a Single CTCF Target Site within the H19 Imprinting Control Region Leads to Loss of Igf2 Imprinting and Complex Patterns of de Novo Methylation upon Maternal Inheritance

    Vinod Pant;Sreenivasulu Kurukuti;Elena Pugacheva;Shaharum Shamsuddin

Frequent Co-Authors

Victor V. Lobanenkov
Victor V. Lobanenkov National Institutes of Health
Andrew P. Feinberg
Andrew P. Feinberg Johns Hopkins University
Rainer Renkawitz
Rainer Renkawitz University of Giessen
Tomas J. Ekström
Tomas J. Ekström Karolinska Institute
Christer Betsholtz
Christer Betsholtz Uppsala University
Erik G. Larsson
Erik G. Larsson Linköping University
Mitsuo Oshimura
Mitsuo Oshimura Tottori University
Erlend B. Smeland
Erlend B. Smeland Oslo University Hospital
Carl-Henrik Heldin
Carl-Henrik Heldin Uppsala University
Philip D. Gregory
Philip D. Gregory Sangamo BioSciences (United States)

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