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Tomas J. Ekström

Tomas J. Ekström

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
11438
World Ranking
14425
National Ranking
219

Overview

Tomas J. Ekström is affiliated with the Karolinska Institute in Sweden. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Within these broader areas, they have contributed notably to subfields including Molecular Biology, Cancer Research, Epidemiology, Pediatrics, Perinatology and Child Health, and Genetics.

The scientist's work primarily addresses topics such as Epigenetics and DNA Methylation, Prenatal Substance Exposure Effects, Genetic Syndromes and Imprinting, Chronic Obstructive Pulmonary Disease (COPD) Research, Dietary Effects on Health, Child Welfare and Adoption, and Substance Abuse Treatment and Outcomes.

Several recent papers authored or co-authored by Tomas J. Ekström include:

  • Monoamine oxidase A genotype and methylation moderate the association of maltreatment and aggressive behaviour, 2020, Behavioural Brain Research
  • Methylome and transcriptome signature of bronchoalveolar cells from multiple sclerosis patients in relation to smoking, 2020, Multiple Sclerosis Journal
  • Chronic Obstructive Pulmonary Disease Is Associated with Epigenome-Wide Differential Methylation in BAL Lung Cells, 2022, American Journal of Respiratory Cell and Molecular Biology
  • Longitudinal genome-wide DNA methylation changes in response to kidney failure replacement therapy, 2022, Scientific Reports
  • Loss of H3K27me3 in WHO grade 3 meningioma, 2022, Brain Tumor Pathology

Frequent co-authors in their research include:

  • Mikael V. Ringh
  • Michael Hagemann-Jensen
  • David Checknita
  • Megha Bendre
  • Erika Comasco

They publish regularly in venues such as Behavioural Brain Research, American Journal of Respiratory Cell and Molecular Biology, Multiple Sclerosis Journal, Scientific Reports, and Brain Tumor Pathology. Behavioural Brain Research is the venue with the highest frequency of their publications.

Best Publications

  • Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis

    Yun Liu;Martin J Aryee;Leonid Padyukov;M Daniele Fallin;M Daniele Fallin

  • Intra-individual change over time in DNA methylation with familial clustering.

    Hans T. Bjornsson;Martin I. Sigurdsson;M. Daniele Fallin;Rafael A. Irizarry

  • The human histone deacetylase family.

    Steven G. Gray;Tomas J. Ekström

  • Impact of inflammation on epigenetic DNA methylation - a novel risk factor for cardiovascular disease?

    P. Stenvinkel;M. Karimi;S. Johansson;J. Axelsson

  • IGF2 is parentally imprinted during human embryogenesis and in the Beckwith–Wiedemann syndrome

    Rolf Ohlsson;Anders Nyström;Susan Pfeifer-Ohlsson;Virpi Töhönen

  • LUMA (LUminometric Methylation Assay)--a high throughput method to the analysis of genomic DNA methylation.

    Mohsen Karimi;Sofia Johansson;Dirk Stach;Martin Corcoran

  • An integrative analysis reveals coordinated reprogramming of the epigenome and the transcriptome in human skeletal muscle after training

    Maléne E Lindholm;Francesco Marabita;David Gomez-Cabrero;Helene Rundqvist

  • An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform.

    Francesco Marabita;Malin Almgren;Maléne E. Lindholm;Sabrina Ruhrmann

  • Sex- and diet-specific changes of imprinted gene expression and DNA methylation in mouse placenta under a high-fat diet.

    Catherine Gallou-Kabani;Anne Gabory;Anne Gabory;Jörg Tost;Mohsen Karimi

  • Histone deacetylase inhibitor Trichostatin A induces global and gene-specific DNA demethylation in human cancer cell lines.

    Jing-Ni Ou;Jérôme Torrisani;Alexander Unterberger;Nadine Provençal

  • Epigenetic aberrations in leukocytes of patients with schizophrenia: association of global DNA methylation with antipsychotic drug treatment and disease onset

    Philippe A. Melas;Maria Rogdaki;Urban Ösby;Martin Schalling

  • DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis

    Lara Kular;Yun Liu;Yun Liu;Sabrina Ruhrmann;Galina Zheleznyakova

  • Molecular cloning of mouse acetylcholinesterase: Tissue distribution of alternatively spliced mRNA species

    Tara L. Rachinsky;Shelley Camp;Ying Li;Tomas J. Ekström

  • Epigenetic modulation at birth – altered DNA-methylation in white blood cells after Caesarean section

    T Schlinzig;S Johansson;A Gunnar;TJ Ekström

  • Using LUMA: a Luminometric-based assay for global DNA-methylation.

    Mohsen Karimi;Sofia Johansson;Tomas J Ekström

  • Methylation changes in the human IGF2 p3 promoter parallel IGF2 expression in the primary tumor, established cell line, and xenograft of a human hepatoblastoma.

    Therése Eriksson;Tony Frisk;Steven G. Gray;Dietrich von Schweinitz

  • Gene-specific and global methylation patterns predict outcome in patients with acute myeloid leukemia.

    S Deneberg;M Grövdal;M Karimi;M Karimi;M Jansson

  • DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation

    Rita Shaknovich;Leandro Cerchietti;Lucas Tsikitas;Matthias Kormaksson

  • In situ activation of the type 2 ryanodine receptor in pancreatic beta cells requires cAMP-dependent phosphorylation.

    Md. Shahidul Islam;Ingo Leibiger;Barbara Leibiger;Daniela Rossi

  • Gap junction-mediated bystander effect in primary cultures of human malignant gliomas with recombinant expression of the HSVtk gene.

    Thomas Asklund;Ioulia B Appelskog;Ole Ammerpohl;Iver A Langmoen

Frequent Co-Authors

Georgy Bakalkin
Georgy Bakalkin Uppsala University
Catharina Larsson
Catharina Larsson Karolinska University Hospital
Andrew P. Feinberg
Andrew P. Feinberg Johns Hopkins University
Jesper Tegnér
Jesper Tegnér King Abdullah University of Science and Technology
Peter Stenvinkel
Peter Stenvinkel Karolinska Institute
Martin Schalling
Martin Schalling Karolinska Institute
Gustav Dallner
Gustav Dallner Karolinska Institute
Lars Terenius
Lars Terenius Karolinska Institute
Herta Flor
Herta Flor Heidelberg University
Peter R. Schofield
Peter R. Schofield Neuroscience Research Australia

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