World's Best Scientists 2026 revealed!
Regina M. Santella

Regina M. Santella

Award Badge
Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
109
Citations
39547
World Ranking
945
National Ranking
575

Medicine

D-Index
111
Citations
40894
World Ranking
5369
National Ranking
2895

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award

Overview

Regina M. Santella is affiliated with Columbia University in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broad areas, they have focused on several subfields including Molecular Biology, Genetics, Oncology, Cancer Research, and Health, Toxicology and Mutagenesis.

The main topics addressed in their work include Epigenetics and DNA Methylation, Effects and risks of endocrine disrupting chemicals, Cancer Risks and Factors, Amyotrophic Lateral Sclerosis Research, BRCA gene mutations in cancer, Nutrition, Genetics, and Disease, and DNA Repair Mechanisms.

Regina M. Santella has contributed to research published in multiple venues, with frequent publications appearing in:

  • UNC Libraries
  • Research Square (Research Square)
  • ISEE Conference Abstracts
  • Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
  • Scientific Reports

The following recent papers highlight some of their published work:

  • MicroRNA-based risk scoring system to identify early-stage oral squamous cell carcinoma patients at high-risk for cancer-specific mortality, 2020, Head & Neck
  • Genome-wide association study identifies high-impact susceptibility loci for HCC in North America, 2024, Hepatology
  • Plasma creatinine and oxidative stress biomarkers in amyotrophic lateral sclerosis, 2020, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
  • Gene expression profiles for low-dose exposure to diethyl phthalate in rodents and humans: a translational study with implications for breast carcinogenesis, 2020, Scientific Reports
  • The trial to assess chelation therapy 2 (TACT2): Rationale and design, 2022, American Heart Journal

Throughout their career, Regina M. Santella has frequently collaborated with several coauthors, including:

  • Susan L. Teitelbaum
  • Alfred I. Neugut
  • Marilie D. Gammon
  • Mary Beth Terry
  • Susan E. Steck

Best Publications

  • Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT).

    Scott M. Lippman;Eric A. Klein;Eric A. Klein;Phyllis J. Goodman;M. Scott Lucia

  • Menarche, menopause, and breast cancer risk: Individual participant meta-analysis, including 118 964 women with breast cancer from 117 epidemiological studies

    N. Hamajima;K. Hirose;K. Tajima;T. Rohan

  • Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

    Kyriaki Michailidou;Jonathan Beesley;Sara Lindstrom;Sander Canisius

  • Type and timing of menopausal hormone therapy and breast cancer risk: individual participant meta-analysis of the worldwide epidemiological evidence

    N. Hamajima;K. Hirose;K. Tajima;T. Rohan

  • Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression.

    Wei Jiang;S. M. Kahn;Ping Zhou;Yu-Jing Zhang

  • Altered expression of the cyclin D1 and retinoblastoma genes in human esophageal cancer.

    Wei Jiang;Yu-Jing Zhang;S. M. Kahn;M. C. Hollstein

  • Significant differences in global genomic DNA methylation by gender and race/ethnicity in peripheral blood

    Fang Fang Zhang;Roberto Cardarelli;Joan Carroll;Kimberly G. Fulda

  • Designing the Selenium and Vitamin E Cancer Prevention Trial (SELECT)

    Scott M. Lippman;Phyllis J. Goodman;Eric A. Klein;Howard L. Parnes

  • DNA methylation in white blood cells: Association with risk factors in epidemiologic studies

    Mary Beth Terry;Lissette Delgado-Cruzata;Neomi Vin-Raviv;Hui Chen Wu

  • Detection of smoking-related covalent DNA adducts in human placenta

    Richard B. Everson;Erika Randerath;Regina M. Santella;Robert C. Cefalo

  • Antioxidant enzyme expression and reactive oxygen species damage in prostatic intraepithelial neoplasia and cancer.

    David G. Bostwick;Erik E. Alexander;Rohini Singh;Ailin Shan

  • Clinical perspective on oxidative stress in sporadic amyotrophic lateral sclerosis.

    Emanuele D’Amico;Pam Factor-Litvak;Regina M. Santella;Hiroshi Mitsumoto

  • Molecular and genetic damage in humans from environmental pollution in Poland.

    Frederica P. Perera;Kari Hemminki;Ewa Gryzbowska;Grazyna Motykiewicz

  • The Breast Cancer Family Registry: an infrastructure for cooperative multinational, interdisciplinary and translational studies of the genetic epidemiology of breast cancer

    Esther M John;John L Hopper;Jeanne C Beck;Julia A Knight

  • Aflatoxin exposure and risk of hepatocellular carcinoma in Taiwan

    Li-Yu Wang;Maureen Hatch;Chien-Jen Chen;Bruce Levin

  • Amplification and overexpression of cyclin D1 in human hepatocellular carcinoma

    Yu-Jing Zhang;Wei Jiang;Chien Jen Chen;Chue Shue Lee

  • Determination of 8-hydroxydeoxyguanosine by an immunoaffinity chromatography-monoclonal antibody-based ELISA.

    Baoyun Yin;Robin M. Whyatt;Frederica P. Perera;Mary C. Randall

  • Recent Developments in Molecular Epidemiology: A Study of the Effects of Environmental Polycyclic Aromatic Hydrocarbons on Birth Outcomes in Poland

    Frederica P. Perera;Robin M. Whyatt;Wieslaw Jedrychowski;Virginia Rauh

  • Environmental toxins and breast cancer on Long Island. II. Organochlorine compound levels in blood.

    Marilie D. Gammon;Mary S. Wolff;Alfred I. Neugut;Sybil M. Eng

  • Environmental toxins and breast cancer on Long Island. I. Polycyclic aromatic hydrocarbon DNA adducts

    Marilie D. Gammon;Regina M. Santella;Alfred I. Neugut;Sybil M. Eng

Frequent Co-Authors

Mary Beth Terry
Mary Beth Terry Columbia University
Marilie D. Gammon
Marilie D. Gammon University of North Carolina at Chapel Hill
Susan L. Teitelbaum
Susan L. Teitelbaum Icahn School of Medicine at Mount Sinai
Alfred I. Neugut
Alfred I. Neugut Columbia University
Chien-Jen Chen
Chien-Jen Chen Academia Sinica
Habibul Ahsan
Habibul Ahsan University of Chicago
Frederica P. Perera
Frederica P. Perera Columbia University
Christine B. Ambrosone
Christine B. Ambrosone Roswell Park Cancer Institute
Esther M. John
Esther M. John Stanford University
Hanina Hibshoosh
Hanina Hibshoosh Columbia University

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