World's Best Scientists 2026 revealed!

Overview

Hanina Hibshoosh is affiliated with Columbia University in the United States and has contributed extensively to research in medicine, with a focus on biochemistry, genetics, and molecular biology.

Their work spans various subfields, including molecular biology, oncology, cancer research, pulmonary and respiratory medicine, and biomedical engineering. Main topics addressed in their studies include:

  • Single-cell and spatial transcriptomics
  • Cancer genomics and diagnostics
  • Epigenetics and DNA methylation
  • Cancer immunotherapy and biomarkers
  • Cancer cells and metastasis
  • Photoacoustic and ultrasonic imaging
  • Cancer-related molecular mechanisms research

Recent publications exemplify the range of Hibshoosh's research focus and include:

  • COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets (2021, Nature)
  • A molecular single-cell lung atlas of lethal COVID-19 (2021, Nature)
  • Dissecting the treatment-naive ecosystem of human melanoma brain metastasis (2022, Cell)
  • A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors (2020, eLife)
  • A MYC and RAS co-activation signature in localized prostate cancer drives bone metastasis and castration resistance (2020, Nature Cancer)

Hibshoosh frequently collaborates with researchers including Hua Guo, Benjamin Izar, Amit Dipak Amin, Alfred I. Neugut, and Andrea Califano, with multiple co-authored publications.

Publication venues where their work has appeared repeatedly include:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Nature
  • Cancer Discovery

Best Publications

  • PTEN, a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

    Jing Li;Clifford Yen;Danny Liaw;Katrina Podsypanina

  • The Immune Landscape of Cancer

    Vésteinn Thorsson;David L Gibbs;Scott D Brown;Denise Wolf

  • Induction of autophagy and inhibition of tumorigenesis by beclin 1.

    Xiao Huan Liang;Saadiya Jackson;Matthew Seaman;Kristy Brown

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

    Xueping Qu;Jie Yu;Govind Bhagat;Norihiko Furuya

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

    Benjamin J. Raphael;Ralph H. Hruban;Andrew J. Aguirre;Richard A. Moffitt

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • PIK3CA Mutations Correlate with Hormone Receptors, Node Metastasis, and ERBB2, and Are Mutually Exclusive with PTEN Loss in Human Breast Carcinoma

    Lao H. Saal;Karolina Holm;Matthew Maurer;Lorenzo Memeo

  • Pathogenic Germline Variants in 10,389 Adult Cancers

    Kuan-Lin Huang;R Jay Mashl;Yige Wu;Deborah I Ritter

  • A molecular single-cell lung atlas of lethal COVID-19.

    Johannes C. Melms;Jana Biermann;Huachao Huang;Yiping Wang

  • COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets.

    Toni M. Delorey;Carly G. K. Ziegler;Graham Heimberg;Rachelly Normand

  • Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity

    Lao H. Saal;Peter Johansson;Karolina Holm;Sofia K. Gruvberger-Saal

  • Erratum: Comprehensive Characterization of Cancer Driver Genes and Mutations (ARTICLE (2018) 173(2) (371–385), (S009286741830237X), (10.1016/j.cell.2018.02.060))

    Matthew H. Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

    Franz X. Schaub;Varsha Dhankani;Ashton C. Berger;Mihir Trivedi

  • Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair

    Lao H Saal;Sofia K Gruvberger-Saal;Camilla Persson;Kristina Lövgren

  • Increased expression of cyclin D1 is an early event in multistage colorectal carcinogenesis

    N Arber;H Hibshoosh;SF Moss;T Sutter

  • Lack of PTEN sequesters CHK1 and initiates genetic instability

    Janusz Puc;Megan Keniry;Hong Shen Li;Tej K. Pandita

  • A secreted PTEN phosphatase that enters cells to alter signaling and survival.

    Benjamin D. Hopkins;Barry Fine;Nicole Steinbach;Nicole Steinbach;Meaghan Dendy

Frequent Co-Authors

Dawn L. Hershman
Dawn L. Hershman Columbia University
Mary Beth Terry
Mary Beth Terry Columbia University
Regina M. Santella
Regina M. Santella Columbia University
Ramon Parsons
Ramon Parsons Icahn School of Medicine at Mount Sinai
Marilie D. Gammon
Marilie D. Gammon University of North Carolina at Chapel Hill
Andreas H. Hielscher
Andreas H. Hielscher New York University
Alfred I. Neugut
Alfred I. Neugut Columbia University
Susan L. Teitelbaum
Susan L. Teitelbaum Icahn School of Medicine at Mount Sinai
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
Andrew D. Cherniack
Andrew D. Cherniack Broad Institute

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