Genetics, DNA mismatch repair, Germline mutation, MLH1 and Colorectal cancer are her primary areas of study. Päivi Peltomäki combines subjects such as Mutation, Gene mutation, Germline and Gene product with her study of DNA mismatch repair. Her Germline mutation research includes themes of Endometrial cancer and Microsatellite instability.
Päivi Peltomäki has included themes like Phenotype and Cancer research in her Microsatellite instability study. Her biological study spans a wide range of topics, including Tumor suppressor gene and MSH2. Her research integrates issues of Family history and Pathology in her study of Colorectal cancer.
The scientist’s investigation covers issues in Genetics, Colorectal cancer, Cancer research, DNA mismatch repair and MLH1. Many of her studies on Genetics apply to Molecular biology as well. Her Colorectal cancer research is multidisciplinary, relying on both Oncology and Pathology.
She has researched Cancer research in several fields, including Germline mutation, Carcinogenesis, Microsatellite instability, Carcinoma and PTEN. The Carcinogenesis study combines topics in areas such as DNA methylation and Loss of heterozygosity. Her work in MLH1 addresses issues such as MSH2, which are connected to fields such as MSH6.
Her primary areas of study are Cancer research, Lynch syndrome, Germline mutation, Epigenetics and Colorectal cancer. Her Cancer research research incorporates themes from Carcinogenesis, Germline, Endometrial cancer and DNA methylation. Her studies in Lynch syndrome integrate themes in fields like MLH1, MSH2 and Microsatellite instability.
Her Germline mutation study combines topics from a wide range of disciplines, such as CpG Island Methylator Phenotype and Gene mutation. In her study, Ethnic origin and Cancer prevention is inextricably linked to Oncology, which falls within the broad field of Colorectal cancer. Her DNA mismatch repair study is concerned with the larger field of Genetics.
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Clues to the pathogenesis of familial colorectal cancer
Lauri A. Aaltonen;Päivi Peltomäki;Fredrick S. Leach;Pertti Sistonen.
Revised Bethesda Guidelines for Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome) and Microsatellite Instability
Asad Umar;C. Richard Boland;Jonathan P. Terdiman;Sapna Syngal.
Journal of the National Cancer Institute (2004)
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
Fredrick S. Leach;Nicholas C. Nicolaides;Nickolas Papadopoulos;Bo Liu.
Mutation of a mutL homolog in hereditary colon cancer
Nickolas Papadopoulos;Nicholas C. Nicolaides;Ying Fei Wei;Steven M. Ruben.
Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.
Joseph F. Costello;Joseph F. Costello;Michael C. Frühwald;Michael C. Frühwald;Dominic J. Smiraglia;Laura J. Rush.
Nature Genetics (2000)
Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer
Heikki J. Järvinen;Markku Aarnio;Harri Mustonen;Katja Aktan–Collan‡.
Cancer risk in mutation carriers of DNA-mismatch-repair genes.
M. Aarnio;R. Sankila;E. Pukkala;R. Salovaara.
International Journal of Cancer (1999)
Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease
L A Aaltonen;R Salovaara;P Kristo;F Canzian.
The New England Journal of Medicine (1998)
Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients
Bo Liu;Ramon Parsons;Nickolas Papadopoulos;Nicholas C. Nicolaides.
Nature Medicine (1996)
Genetic Mapping of a Locus Predisposing to Human Colorectal Cancer
Päivi Peltomäki;Lauri A. Aaltonen;Pertti Sistonen;Lea Pylkkänen.
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