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Medicine

D-Index
139
Citations
68635
World Ranking
1768
National Ranking
1010

Overview

Lee M. Ellis is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research contributions span multiple aspects of cancer biology and treatment, with a particular focus on colorectal and other solid cancers.

The scientist's recent publications include studies on cancer prognosis and treatment outcomes. Notable papers include:

  • "Tumor Sidedness, Recurrence, and Survival After Curative Resection of Localized Colon Cancer" (2020) published in Clinical Colorectal Cancer
  • "Overall Survival in Phase 3 Clinical Trials and the Surveillance, Epidemiology, and End Results Database in Patients With Metastatic Colorectal Cancer, 1986-2016" (2022) published in JAMA Network Open
  • "Sex Representation in Clinical Trials Associated with FDA Cancer Drug Approvals Differs Between Solid and Hematologic Malignancies" (2020) published in The Oncologist
  • "Evidence generation and reproducibility in cell and gene therapy research: A call to action" (2021) published in Molecular Therapy - Methods & Clinical Development
  • "Metformin bicarbonate-mediated efficient RNAi for precise targeting of TP53 deficiency in colon and rectal cancers" (2022) published in Nano Today

Frequent coauthors collaborating with Lee M. Ellis include:

  • Rajat Bhattacharya
  • Fan Fan
  • Susmita Ghosh
  • Reid T. Powell
  • Clifford Stephan

The primary publication venues for their research encompass:

  • Cancer Research
  • Molecular Cancer Therapeutics
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Colorectal Cancer
  • JAMA Network Open

Lee M. Ellis's work is anchored in the fields of Medicine as well as Biochemistry, Genetics, and Molecular Biology. Their specific research subfields include Oncology, Molecular Biology, Cancer Research, Pathology and Forensic Medicine, and Pulmonary and Respiratory Medicine.

The main topics addressed in their research focus on:

  • Colorectal Cancer Treatments and Studies
  • Cancer Genomics and Diagnostics
  • PI3K/AKT/mTOR signaling in cancer
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Genetic factors in colorectal cancer
  • Cancer Treatment and Pharmacology
  • Lung Cancer Treatments and Mutations

Best Publications

  • Role of the Vascular Endothelial Growth Factor Pathway in Tumor Growth and Angiogenesis

    Daniel J. Hicklin;Lee M. Ellis

  • Drug development: Raise standards for preclinical cancer research

    C. Glenn Begley;Lee M. Ellis

  • Recurrence and Outcomes Following Hepatic Resection, Radiofrequency Ablation, and Combined Resection/Ablation for Colorectal Liver Metastases

    Eddie K. Abdalla;Jean-Nicolas Vauthey;Lee M. Ellis;Vickie Ellis

  • VEGF-targeted therapy: mechanisms of anti-tumour activity

    Lee M. Ellis;Daniel J. Hicklin

  • Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

    Guilian Niu;Kenneth L Wright;Mei Huang;Lanxi Song

  • Radiofrequency Ablation of Unresectable Primary and Metastatic Hepatic Malignancies: Results in 123 Patients

    Steven A. Curley;Francesco Izzo;Paolo Delrio;Lee M. Ellis

  • The implications of angiogenesis for the biology and therapy of cancer metastasis

    Isaiah J. Fidler;Lee M. Ellis

  • Insulin-like Growth Factor 1 Induces Hypoxia-inducible Factor 1-mediated Vascular Endothelial Growth Factor Expression, Which is Dependent on MAP Kinase and Phosphatidylinositol 3-Kinase Signaling in Colon Cancer Cells *

    Ryo Fukuda;Kiichi Hirota;Fan Fan;Young Do Jung

  • Radiofrequency ablation of hepatocellular cancer in 110 patients with cirrhosis.

    Steven A. Curley;Francesco Izzo;Lee M. Ellis;J. Nicolas Vauthey

  • Simplified Staging for Hepatocellular Carcinoma

    Jean Nicolas Vauthey;Gregory Y. Lauwers;Nestor F. Esnaola;Kim Anh Do

  • Antiangiogenic therapy in oncology: current status and future directions.

    Gordon C Jayson;Robert Kerbel;Lee M Ellis;Adrian L Harris

  • Pathologic Response to Preoperative Chemotherapy: A New Outcome End Point After Resection of Hepatic Colorectal Metastases

    Dan G. Blazer;Yoji Kishi;Dipen M. Maru;Scott Kopetz

  • HIF-1α, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas

    Michael J Gray;Jing Zhang;Jing Zhang;Lee M Ellis;Gregg L Semenza

  • Angiogenesis and breast cancer metastasis

    Lee M Ellis;Isaiah J Fidler

  • Angiogenesis and metastasis

    Lee M Ellis;Isaiah J Fidler

  • Antiangiogenic Therapy Targeting the Tyrosine Kinase Receptor for Vascular Endothelial Growth Factor Receptor Inhibits the Growth of Colon Cancer Liver Metastasis and Induces Tumor and Endothelial Cell Apoptosis

    Raymond M. Shaheen;Darren W. Davis;Wenbiao Liu;Brian K. Zebrowski

  • Endothelial Cells Promote the Colorectal Cancer Stem Cell Phenotype through a Soluble Form of Jagged-1

    Jia Lu;Xiangcang Ye;Fan Fan;Ling Xia

  • Bevacizumab improves pathologic response and protects against hepatic injury in patients treated with oxaliplatin‐based chemotherapy for colorectal liver metastases

    Dario Ribero;Huamin Wang;Matteo Donadon;Daria Zorzi

  • Expression and function of vascular endothelial growth factor receptor-1 on human colorectal cancer cells

    Fan Fan;Jane S Wey;Marya F McCarty;Anna Belcheva

  • Phase II trial of infusional fluorouracil, irinotecan, and bevacizumab for metastatic colorectal cancer: efficacy and circulating angiogenic biomarkers associated with therapeutic resistance.

    Scott Kopetz;Paulo M. Hoff;Jeffrey S. Morris;Robert A. Wolff

Frequent Co-Authors

Corazon D. Bucana
Corazon D. Bucana The University of Texas MD Anderson Cancer Center
Steven A. Curley
Steven A. Curley The University of Texas MD Anderson Cancer Center
Jean Nicolas Vauthey
Jean Nicolas Vauthey The University of Texas MD Anderson Cancer Center
Daniel J. Hicklin
Daniel J. Hicklin Eli Lilly (United States)
Barry W. Feig
Barry W. Feig The University of Texas MD Anderson Cancer Center
Isaiah J. Fidler
Isaiah J. Fidler The University of Texas MD Anderson Cancer Center
Karen R. Cleary
Karen R. Cleary The University of Texas MD Anderson Cancer Center
Gary E. Gallick
Gary E. Gallick The University of Texas MD Anderson Cancer Center
Robert A. Wolff
Robert A. Wolff The University of Texas MD Anderson Cancer Center
James L. Abbruzzese
James L. Abbruzzese Duke University

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