World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
131
Citations
94819
World Ranking
246
National Ranking
128

Medicine

D-Index
136
Citations
100486
World Ranking
1939
National Ranking
1103

Research.com Recognitions

  • 2002 - William Allan Award, the American Society of Human Genetics
  • 2002 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1997 - Member of the National Academy of Sciences
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Albert de la Chapelle was affiliated with The Ohio State University in the United States. Their research primarily focused on the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, contributing extensively to Genetics, Pathology and Forensic Medicine, Oncology, Hematology, and Molecular Biology.

The scientist's work concentrated on multiple main topics including:

  • Genetic factors in colorectal cancer
  • Genetic Associations and Epidemiology
  • Acute Myeloid Leukemia Research
  • Thyroid Cancer Diagnosis and Treatment
  • Colorectal Cancer Screening and Detection
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Acute Lymphoblastic Leukemia research

Albert de la Chapelle frequently published research in notable venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The American Journal of Human Genetics
  • Nature Communications
  • Proceedings of the National Academy of Sciences
  • Thyroid

Their recent papers included the following:

  • Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk, 2020, The American Journal of Human Genetics
  • Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study, 2020, BMC Medicine
  • Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells, 2020, Nature
  • GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer, 2020, Nature Communications
  • Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study, 2021, The Lancet Oncology

Albert de la Chapelle collaborated frequently with other researchers, notably:

  • Heather Hampel
  • Loïc Le Marchand
  • Steven Gallinger
  • Mark A. Jenkins
  • Temitope O. Keku

The scientist received several awards, including:

  • William Allan Award, the American Society of Human Genetics, 2002
  • Fellow of the American Association for the Advancement of Science (AAAS), 2002
  • Member of the National Academy of Sciences, 1997
  • Member of the Association of American Physicians

Best Publications

  • PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

    Dung T. Le;Jennifer N. Uram;Hao Wang;Bjarne R. Bartlett

  • Revised Bethesda Guidelines for Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome) and Microsatellite Instability

    Asad Umar;C. Richard Boland;Jonathan P. Terdiman;Sapna Syngal

  • Clues to the pathogenesis of familial colorectal cancer

    Lauri A. Aaltonen;Päivi Peltomäki;Fredrick S. Leach;Pertti Sistonen

  • Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

    Fredrick S. Leach;Nicholas C. Nicolaides;Nickolas Papadopoulos;Bo Liu

  • Hereditary Colorectal Cancer

    Henry T. Lynch;Albert de la Chapelle

  • Mutation of a mutL homolog in hereditary colon cancer

    Nickolas Papadopoulos;Nicholas C. Nicolaides;Ying Fei Wei;Steven M. Ruben

  • Mutations of two PMS homologues in hereditary nonpolyposis colon cancer.

    Nicholas C. Nicolaides;Nickolas Papadopoulos;Bo Liu;Ying Fei Weit

  • A serine/threonine kinase gene defective in Peutz–Jeghers syndrome

    A Hemminki;D Markie;I Tomlinson;E Avizienyte

  • Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene

    Renee Reijo;Tien-Yi Lee;Pia Salo;Raaji Alagappan

  • Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer

    Heikki J. Järvinen;Markku Aarnio;Harri Mustonen;Katja Aktan–Collan‡

  • Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer).

    Heather Hampel;Wendy L. Frankel;Edward Martin;Mark Arnold

  • The role of microRNA genes in papillary thyroid carcinoma

    Hulling He;Krystian Jazdzewski;Wei Li;Sandya Liyanarachchi

  • Cancer risk in mutation carriers of DNA-mismatch-repair genes.

    M. Aarnio;R. Sankila;E. Pukkala;R. Salovaara

  • Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease

    L A Aaltonen;R Salovaara;P Kristo;F Canzian

  • Hypermutability and mismatch repair deficiency in RER+ tumor cells

    Ramon Parsons;Guo Min Li;Matthew J. Longley;Woei horng Fang;Woei horng Fang

  • Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients

    Bo Liu;Ramon Parsons;Nickolas Papadopoulos;Nicholas C. Nicolaides

  • Genetic Mapping of a Locus Predisposing to Human Colorectal Cancer

    Päivi Peltomäki;Lauri A. Aaltonen;Pertti Sistonen;Lea Pylkkänen

  • MUTATION IN THE FOLLICLE-STIMULATING HORMONE RECEPTOR GENE CAUSES HEREDITARY HYPERGONADOTROPIC OVARIAN FAILURE

    Kristiina Aittomäki;Kristiina Aittomäki;JoséLuis Dieguez Lucena;JoséLuis Dieguez Lucena;Pirjo Pakarinen;Pertti Sistonen

  • Genetic susceptibility to non-polyposis colorectal cancer

    Henry T Lynch;Albert de la Chapelle

  • The sex-determining region of the human Y chromosome encodes a finger protein

    David C. Page;Rebecca Mosher;Elizabeth M. Simpson;Elizabeth M.C. Fisher

Frequent Co-Authors

Heather Hampel
Heather Hampel The Ohio State University
Sandya Liyanarachchi
Sandya Liyanarachchi The Ohio State University
Clara D. Bloomfield
Clara D. Bloomfield The Ohio State University
Päivi Peltomäki
Päivi Peltomäki University of Helsinki
Krzysztof Mrózek
Krzysztof Mrózek The Ohio State University
Daniel D. Buchanan
Daniel D. Buchanan University of Melbourne
Polly A. Newcomb
Polly A. Newcomb Fred Hutchinson Cancer Research Center
John C. Byrd
John C. Byrd University of Pittsburgh Cancer Institute
Bayard L. Powell
Bayard L. Powell Wake Forest University
Ludmila Vodickova
Ludmila Vodickova Charles University

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