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Medicine

D-Index
165
Citations
133396
World Ranking
619
National Ranking
354

Overview

Henry T. Lynch was affiliated with Creighton University in the United States. Their research centered primarily on genetics and oncology, with a strong focus on hereditary cancer syndromes, particularly regarding BRCA gene mutations.

The scientist's most frequently covered main fields of study included Medicine and Biochemistry, Genetics and Molecular Biology. Within these, their work contributed notably to subfields such as Genetics, Pathology and Forensic Medicine, Oncology, Cancer Research, and Public Health, Environmental and Occupational Health.

The following main research topics were recurrent throughout their publications:

  • BRCA gene mutations in cancer
  • Cancer Genomics and Diagnostics
  • Genetic factors in colorectal cancer
  • Global Cancer Incidence and Screening
  • Lymphoma Diagnosis and Treatment
  • Ethics in Clinical Research
  • Chronic Lymphocytic Leukemia Research

Some of the prominent papers authored or co-authored by Henry T. Lynch included:

  • "Predictors of long-term cancer-related distress among female BRCA1 and BRCA2 mutation carriers without a cancer diagnosis: an international analysis" (2020), published in British Journal of Cancer
  • "Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction" (2020), published in UNC Libraries
  • "Preferences for breast cancer prevention among women with a BRCA1 or BRCA2 mutation" (2020), published in Hereditary Cancer in Clinical Practice
  • "In search of genetic factors predisposing to familial hairy cell leukemia (HCL): exome-sequencing of four multiplex HCL pedigrees" (2020), published in Leukemia
  • "Gene and pathway based burden analyses in familial lymphoid cancer cases: Rare variants in immune pathway genes" (2023), published in PLoS ONE

The scientist collaborated frequently with several colleagues, including Carrie Snyder, D. Gareth Evans, Kelly Metcalfe, Carol Mansfield, and Geoffrey J. Lindeman. These co-authors appeared multiple times alongside Henry T. Lynch in research papers.

Henry T. Lynch published regularly in venues such as UNC Libraries, British Journal of Cancer, Hereditary Cancer in Clinical Practice, Leukemia, and PLoS ONE, indicating a broad engagement across journals specializing in cancer genetics and hematologic malignancies.

Best Publications

  • Identification of the breast cancer susceptibility gene BRCA2

    Wooster R;Bignell G;Lancaster J;Swift S

  • Genetic Heterogeneity and Penetrance Analysis of the BRCA1 and BRCA2 Genes in Breast Cancer Families

    D Ford;D F Easton;M Stratton;S Narod

  • Revised Bethesda Guidelines for Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome) and Microsatellite Instability

    Asad Umar;C. Richard Boland;Jonathan P. Terdiman;Sapna Syngal

  • New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC.

    Hans F.A. Vasen;Patrice Watson;Jukka–Pekka Mecklin;Henry T. Lynch

  • The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC).

    H. F. A. Vasen;J. P. Mecklin;P. Meera Khan;H. T. Lynch

  • Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

    Fredrick S. Leach;Nicholas C. Nicolaides;Nickolas Papadopoulos;Bo Liu

  • Hereditary Colorectal Cancer

    Henry T. Lynch;Albert de la Chapelle

  • HNPCC (Lynch Syndrome): Differential Diagnosis, Molecular Genetics and Management - a Review

    Henry T Lynch;Jane F Lynch;Trudy G Shaw;Jan Lubiński

  • Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13

    Richard Wooster;Susan L. Neuhausen;Jonathan Mangion;Yvette Quirk

  • Mutation of a mutL homolog in hereditary colon cancer

    Nickolas Papadopoulos;Nicholas C. Nicolaides;Ying Fei Wei;Steven M. Ruben

  • Prophylactic Oophorectomy in Carriers of BRCA1 or BRCA2 Mutations

    Timothy R. Rebbeck;Henry T. Lynch;Susan L. Neuhausen;Steven A. Narod

  • Association of Risk-Reducing Surgery in BRCA1 or BRCA2 Mutation Carriers With Cancer Risk and Mortality

    Susan M. Domchek;Tara M. Friebel;Christian F. Singer;D. Gareth Evans

  • Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: An updated review

    Henry T. Lynch;Thomas C. Smyrk;Patrice Watson;Stephen J. Lanspa

  • Bilateral Prophylactic Mastectomy Reduces Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers: The PROSE Study Group

    Timothy R. Rebbeck;Tara Friebel;Henry T. Lynch;Susan L. Neuhausen

  • A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: Meeting Highlights and Bethesda Guidelines

    Miguel A Rodriguez-Bigas;C. R. Boland;Stanley R Hamilton;D. E. Henson

  • Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients

    Bo Liu;Ramon Parsons;Nickolas Papadopoulos;Nicholas C. Nicolaides

  • Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial

    John Burn;Anne Marie Gerdes;Finlay MacRae;Jukka Pekka Mecklin

  • Genetic susceptibility to non-polyposis colorectal cancer

    Henry T Lynch;Albert de la Chapelle

  • Erratum: Identification of the breast cancer susceptibility gene BRCA2

    Richard Wooster;Graham Bignell;Jonathan Lancaster;Sally Swift

  • Historical and Natural Cancer History Facets of the Lynch Syndromes

    Henry T. Lynch;Stephen J. Lanspa;Thomas C. Smyrk;Robert J. Fitzgibbons

Frequent Co-Authors

Jane F. Lynch
Jane F. Lynch Creighton University
Steven A. Narod
Steven A. Narod University of Toronto
Patrice Watson
Patrice Watson Creighton University
Jan Lubinski
Jan Lubinski Pomeranian Medical University
William D. Foulkes
William D. Foulkes McGill University
Thomas C. Smyrk
Thomas C. Smyrk Mayo Clinic
Susan L. Neuhausen
Susan L. Neuhausen City Of Hope National Medical Center
Nadine Tung
Nadine Tung Beth Israel Deaconess Medical Center
Parviz Ghadirian
Parviz Ghadirian University of Montreal
Olufunmilayo I. Olopade
Olufunmilayo I. Olopade University of Chicago

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