D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 100 Citations 40,879 557 World Ranking 4881 National Ranking 2727

Research.com Recognitions

Awards & Achievements

2018 - Member of the National Academy of Medicine (NAM)

Member of the Association of American Physicians

Overview

What is she best known for?

The fields of study she is best known for:

  • Cancer
  • Internal medicine
  • Gene

Susan M. Domchek mainly investigates Breast cancer, Internal medicine, Cancer, Oncology and Gynecology. In her research on the topic of Breast cancer, Estrogen receptor is strongly related with Gene mutation. Her research integrates issues of Germline mutation, Surgery and Pathology in her study of Internal medicine.

Her Cancer research incorporates themes from Genetic testing, Cancer research and Bioinformatics. The various areas that Susan M. Domchek examines in her Oncology study include Olaparib, Tolerability, Metastatic breast cancer, Case-control study and Prostate cancer. The Gynecology study combines topics in areas such as Male breast cancer, Epidemiology, Obstetrics, Prospective cohort study and Cancer prevention.

Her most cited work include:

  • Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial (1797 citations)
  • Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer (1152 citations)
  • Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation (1004 citations)

What are the main themes of her work throughout her whole career to date?

Her scientific interests lie mostly in Breast cancer, Internal medicine, Oncology, Cancer and Ovarian cancer. Her Breast cancer research incorporates elements of Cancer research, Gynecology, Family history and Single-nucleotide polymorphism. Her study in Gynecology is interdisciplinary in nature, drawing from both Risk factor and Obstetrics.

The concepts of her Internal medicine study are interwoven with issues in Germline mutation and Olaparib. Her Oncology research integrates issues from PARP inhibitor, Chemotherapy, Gene mutation and Hazard ratio. Her Cancer study integrates concerns from other disciplines, such as CHEK2, Prospective cohort study, Odds ratio and Penetrance.

She most often published in these fields:

  • Breast cancer (61.11%)
  • Internal medicine (53.77%)
  • Oncology (46.23%)

What were the highlights of her more recent work (between 2017-2021)?

  • Internal medicine (53.77%)
  • Oncology (46.23%)
  • Breast cancer (61.11%)

In recent papers she was focusing on the following fields of study:

Her primary scientific interests are in Internal medicine, Oncology, Breast cancer, Cancer and Genetic testing. The Internal medicine study combines topics in areas such as Polygenic risk score, Olaparib and Cancer susceptibility. Her work is dedicated to discovering how Oncology, Germline are connected with Somatic cell and other disciplines.

She has researched Breast cancer in several fields, including CHEK2, Ejection fraction, Family history and Gene mutation. Susan M. Domchek interconnects Germline mutation, Li–Fraumeni syndrome and Proportional hazards model in the investigation of issues within Cancer. Her Genetic testing study combines topics in areas such as Usual care, Randomized controlled trial, MEDLINE, Bioinformatics and Genetic counseling.

Between 2017 and 2021, her most popular works were:

  • OlympiAD final overall survival and tolerability results: Olaparib versus chemotherapy treatment of physician’s choice in patients with a germline BRCA mutation and HER2-negative metastatic breast cancer (129 citations)
  • Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations (100 citations)
  • Genetic/familial high-risk assessment: Breast, ovarian, and pancreatic, version 1.2020 featured updates to the NCCN guidelines (94 citations)

In her most recent research, the most cited papers focused on:

  • Cancer
  • Gene
  • Internal medicine

The scientist’s investigation covers issues in Internal medicine, Oncology, Breast cancer, Cancer and Olaparib. Her studies deal with areas such as Random assignment and Anxiety as well as Internal medicine. The various areas that Susan M. Domchek examines in her Oncology study include Progressive disease, Chemotherapy, Ovarian cancer, Prospective cohort study and Complex segregation analysis.

She is studying Cancer Family, which is a component of Breast cancer. Her Cancer study incorporates themes from Germline mutation, Computational biology and Proportional hazards model. Her work carried out in the field of Olaparib brings together such families of science as Cancer research, Metastatic breast cancer, PARP inhibitor and Durvalumab.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation

Mark Robson;Seock Ah Im;Elżbieta Senkus;Binghe Xu.
The New England Journal of Medicine (2017)

2054 Citations

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial

Andrew Tutt;Mark Robson;Judy E Garber;Susan M Domchek.
The Lancet (2010)

2028 Citations

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer

A Tutt;M Robson;J E Garber;S M Domchek.
The Lancet (2010)

1964 Citations

Olaparib Monotherapy in Patients With Advanced Cancer and a Germline BRCA1/2 Mutation

Bella Kaufman;Ronnie Shapira-Frommer;Rita K. Schmutzler;M. William Audeh.
Journal of Clinical Oncology (2015)

1587 Citations

Association of Risk-Reducing Surgery in BRCA1 or BRCA2 Mutation Carriers With Cancer Risk and Mortality

Susan M. Domchek;Tara M. Friebel;Christian F. Singer;D. Gareth Evans.
JAMA (2010)

1437 Citations

Meta-analysis of Risk Reduction Estimates Associated With Risk-Reducing Salpingo-oophorectomy in BRCA1 or BRCA2 Mutation Carriers

Timothy R. Rebbeck;Noah D. Kauff;Susan M. Domchek.
Journal of the National Cancer Institute (2009)

990 Citations

Breast-Cancer Risk in Families with Mutations in PALB2

A. C. Antoniou;S. Casadei;T. Heikkinen;D. Barrowdale.
The New England Journal of Medicine (2014)

907 Citations

Gene-Panel Sequencing and the Prediction of Breast-Cancer Risk

Douglas Frederick Easton;Paul David Pharoah;Antonis C. Antoniou;Marc Derek Tischkowitz.
The New England Journal of Medicine (2015)

836 Citations

American Society of Clinical Oncology Policy Statement Update: Genetic and Genomic Testing for Cancer Susceptibility

Mark E. Robson;Mark E. Robson;Angela R. Bradbury;Banu K Arun;Susan M. Domchek.
Journal of Clinical Oncology (2010)

740 Citations

Risk-Reducing Salpingo-Oophorectomy for the Prevention of BRCA1- and BRCA2-Associated Breast and Gynecologic Cancer: A Multicenter, Prospective Study

Noah D. Kauff;Susan M. Domchek;Tara M. Friebel;Mark E. Robson.
Journal of Clinical Oncology (2008)

649 Citations

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