D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 44 Citations 5,928 132 World Ranking 13863 National Ranking 91

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

His primary areas of investigation include Biochemistry, Avidin, Biotinylation, Biotin and Streptavidin. Markku S. Kulomaa usually deals with Biochemistry and limits it to topics linked to Polyclonal antibodies and Oviduct, Molecular cloning and Monoclonal antibody. Markku S. Kulomaa specializes in Avidin, namely Biotin binding.

His Biotinylation research is under the purview of Molecular biology. His research integrates issues of Complementary DNA, cDNA library, Pinocytosis, Cell biology and Endocytic cycle in his study of Molecular biology. His Biotin research incorporates elements of Golgi apparatus, Endoplasmic reticulum, Secretory pathway, Membrane and Organelle.

His most cited work include:

  • Genetically engineered avidins and streptavidins. (260 citations)
  • Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes. (220 citations)
  • Brave new (strept)avidins in biotechnology (172 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Avidin, Biochemistry, Biotin, Molecular biology and Biotinylation. His Avidin research includes themes of Protein structure, Protein engineering, Oviduct and Streptavidin. His Biotin study combines topics in areas such as Plasma protein binding, Protein family, Dimer, Protein quaternary structure and Binding site.

His study in Molecular biology is interdisciplinary in nature, drawing from both Complementary DNA, Messenger RNA, Gene expression, Gene and Radioimmunoassay. He interconnects Endocytosis and Cell biology in the investigation of issues within Biotinylation. As part of the same scientific family, he usually focuses on Endocytosis, concentrating on Endosome and intersecting with Immunoelectron microscopy, Pinocytosis and Internalization.

He most often published in these fields:

  • Avidin (68.93%)
  • Biochemistry (48.02%)
  • Biotin (35.03%)

What were the highlights of his more recent work (between 2009-2019)?

  • Avidin (68.93%)
  • Biochemistry (48.02%)
  • Biotin (35.03%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Avidin, Biochemistry, Biotin, Biotinylation and Streptavidin. His Avidin study integrates concerns from other disciplines, such as Covalent bond, Crystallography, Maleimide, Protein engineering and Phage display. His biological study spans a wide range of topics, including Force spectroscopy, Protein subunit, Mutant and Energy landscape.

His Biotinylation study deals with Nanotechnology intersecting with Nano- and Biofilm. His Streptavidin study combines topics from a wide range of disciplines, such as Homology modeling and Protein Data Bank. His Protein structure research includes themes of Protein biosynthesis, Structural similarity, Tetramer and Gene family.

Between 2009 and 2019, his most popular works were:

  • Chimeric avidin shows stability against harsh chemical conditions-biochemical analysis and 3D structure. (33 citations)
  • Production and characterization of virus-like particles and the P domain protein of GII.4 norovirus. (30 citations)
  • Purification of norovirus-like particles (VLPs) by ion exchange chromatography. (29 citations)

In his most recent research, the most cited papers focused on:

  • DNA
  • Gene
  • Enzyme

The scientist’s investigation covers issues in Avidin, Biochemistry, Biotin, Biotinylation and Virology. His Isothermal titration calorimetry, Peptide sequence and Zebrafish study, which is part of a larger body of work in Biochemistry, is frequently linked to Surface charge, bridging the gap between disciplines. His Biotin research is multidisciplinary, incorporating elements of Combinatorial chemistry and Cellulose acetate.

His Biotinylation study combines topics in areas such as Conjugated system, Nonspecific binding, Mutant, Biosensor and Streptavidin. His Streptavidin research is multidisciplinary, incorporating perspectives in Maleimide, Binding site and Ligand. His study on Virology also encompasses disciplines like

  • Ion chromatography which intersects with area such as Viral Myocarditis, Immunization, Immune system and Vaccination,
  • Virus-like particle that connect with fields like Protein domain, Immunostaining, Escherichia coli, Microbiology and Antibody.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Genetically engineered avidins and streptavidins.

O. H. Laitinen;V. P. Hytönen;H. R. Nordlund;M. S. Kulomaa.
Cellular and Molecular Life Sciences (2006)

356 Citations

Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes.

Mika Hilvo;Lina Baranauskiene;Anna Maria Salzano;Andrea Scaloni.
Journal of Biological Chemistry (2008)

295 Citations

Brave new (strept)avidins in biotechnology

Olli H. Laitinen;Henri R. Nordlund;Vesa P. Hytönen;Markku S. Kulomaa.
Trends in Biotechnology (2007)

231 Citations

Baculovirus-mediated periadventitial gene transfer to rabbit carotid artery.

Airenne Kj;Hiltunen Mo;Turunen Mp;Turunen Am.
Gene Therapy (2000)

209 Citations

Organelle pH studies using targeted avidin and fluorescein-biotin.

Minnie M Wu;Juan Llopis;Stephen Adams;J Michael McCaffery;J Michael McCaffery.
Chemistry & Biology (2000)

205 Citations

Internalization of novel non-viral vector TAT-streptavidin into human cells

Johanna Rinne;Brian Albarran;Juulia Jylhävä;Teemu O Ihalainen.
BMC Biotechnology (2007)

159 Citations

Isolation and Characterization of Novosphingobium sp. Strain MT1, a Dominant Polychlorophenol-Degrading Strain in a Groundwater Bioremediation System

Marja A. Tiirola;Minna K. Männistö;Jaakko A. Puhakka;Markku S. Kulomaa.
Applied and Environmental Microbiology (2002)

152 Citations

Recombinant NeutraLite avidin: a non-glycosylated, acidic mutant of chicken avidin that exhibits high affinity for biotin and low non-specific binding properties.

Ari T. Marttila;Olli H. Laitinen;Kari J. Airenne;Tikva Kulik.
FEBS Letters (2000)

132 Citations

Baculovirus Capsid Display: A Novel Tool for Transduction Imaging

Sari P. Kukkonen;Kari J. Airenne;Varpu Marjomäki;Olli H. Laitinen.
Molecular Therapy (2003)

129 Citations

Enhanced gene delivery by avidin-displaying baculovirus.

Jani K Räty;Kari J Airenne;Ari T Marttila;Varpu Marjomäki.
Molecular Therapy (2004)

124 Citations

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