His primary areas of investigation include Biochemistry, Avidin, Biotinylation, Biotin and Streptavidin. Markku S. Kulomaa usually deals with Biochemistry and limits it to topics linked to Polyclonal antibodies and Oviduct, Molecular cloning and Monoclonal antibody. Markku S. Kulomaa specializes in Avidin, namely Biotin binding.
His Biotinylation research is under the purview of Molecular biology. His research integrates issues of Complementary DNA, cDNA library, Pinocytosis, Cell biology and Endocytic cycle in his study of Molecular biology. His Biotin research incorporates elements of Golgi apparatus, Endoplasmic reticulum, Secretory pathway, Membrane and Organelle.
His scientific interests lie mostly in Avidin, Biochemistry, Biotin, Molecular biology and Biotinylation. His Avidin research includes themes of Protein structure, Protein engineering, Oviduct and Streptavidin. His Biotin study combines topics in areas such as Plasma protein binding, Protein family, Dimer, Protein quaternary structure and Binding site.
His study in Molecular biology is interdisciplinary in nature, drawing from both Complementary DNA, Messenger RNA, Gene expression, Gene and Radioimmunoassay. He interconnects Endocytosis and Cell biology in the investigation of issues within Biotinylation. As part of the same scientific family, he usually focuses on Endocytosis, concentrating on Endosome and intersecting with Immunoelectron microscopy, Pinocytosis and Internalization.
His primary scientific interests are in Avidin, Biochemistry, Biotin, Biotinylation and Streptavidin. His Avidin study integrates concerns from other disciplines, such as Covalent bond, Crystallography, Maleimide, Protein engineering and Phage display. His biological study spans a wide range of topics, including Force spectroscopy, Protein subunit, Mutant and Energy landscape.
His Biotinylation study deals with Nanotechnology intersecting with Nano- and Biofilm. His Streptavidin study combines topics from a wide range of disciplines, such as Homology modeling and Protein Data Bank. His Protein structure research includes themes of Protein biosynthesis, Structural similarity, Tetramer and Gene family.
The scientist’s investigation covers issues in Avidin, Biochemistry, Biotin, Biotinylation and Virology. His Isothermal titration calorimetry, Peptide sequence and Zebrafish study, which is part of a larger body of work in Biochemistry, is frequently linked to Surface charge, bridging the gap between disciplines. His Biotin research is multidisciplinary, incorporating elements of Combinatorial chemistry and Cellulose acetate.
His Biotinylation study combines topics in areas such as Conjugated system, Nonspecific binding, Mutant, Biosensor and Streptavidin. His Streptavidin research is multidisciplinary, incorporating perspectives in Maleimide, Binding site and Ligand. His study on Virology also encompasses disciplines like
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Genetically engineered avidins and streptavidins.
O. H. Laitinen;V. P. Hytönen;H. R. Nordlund;M. S. Kulomaa.
Cellular and Molecular Life Sciences (2006)
Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes.
Mika Hilvo;Lina Baranauskiene;Anna Maria Salzano;Andrea Scaloni.
Journal of Biological Chemistry (2008)
Brave new (strept)avidins in biotechnology
Olli H. Laitinen;Henri R. Nordlund;Vesa P. Hytönen;Markku S. Kulomaa.
Trends in Biotechnology (2007)
Baculovirus-mediated periadventitial gene transfer to rabbit carotid artery.
Airenne Kj;Hiltunen Mo;Turunen Mp;Turunen Am.
Gene Therapy (2000)
Organelle pH studies using targeted avidin and fluorescein-biotin.
Minnie M Wu;Juan Llopis;Stephen Adams;J Michael McCaffery;J Michael McCaffery.
Chemistry & Biology (2000)
Internalization of novel non-viral vector TAT-streptavidin into human cells
Johanna Rinne;Brian Albarran;Juulia Jylhävä;Teemu O Ihalainen.
BMC Biotechnology (2007)
Isolation and Characterization of Novosphingobium sp. Strain MT1, a Dominant Polychlorophenol-Degrading Strain in a Groundwater Bioremediation System
Marja A. Tiirola;Minna K. Männistö;Jaakko A. Puhakka;Markku S. Kulomaa.
Applied and Environmental Microbiology (2002)
Recombinant NeutraLite avidin: a non-glycosylated, acidic mutant of chicken avidin that exhibits high affinity for biotin and low non-specific binding properties.
Ari T. Marttila;Olli H. Laitinen;Kari J. Airenne;Tikva Kulik.
FEBS Letters (2000)
Baculovirus Capsid Display: A Novel Tool for Transduction Imaging
Sari P. Kukkonen;Kari J. Airenne;Varpu Marjomäki;Olli H. Laitinen.
Molecular Therapy (2003)
Enhanced gene delivery by avidin-displaying baculovirus.
Jani K Räty;Kari J Airenne;Ari T Marttila;Varpu Marjomäki.
Molecular Therapy (2004)
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