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D-Index & Metrics

Chemistry

D-Index
90
Citations
28182
World Ranking
2075
National Ranking
15

Research.com Recognitions

  • 1993 - Member of the National Academy of Medicine (NAM)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Meir Wilchek is affiliated with the Weizmann Institute of Science in Israel and has contributed to research primarily in the fields of Medicine, Neuroscience, and Biochemistry, Genetics and Molecular Biology. Their work bridges a variety of subfields including Physiology, Molecular Biology, Pharmacology, Cellular and Molecular Neuroscience, and Cognitive Neuroscience.

Their recent publications focus heavily on neurological and molecular studies, particularly related to neurodegenerative diseases. Notable papers include:

  • Peptide Interference with APP and Tau Association: Relevance to Alzheimer's Disease Amelioration, 2020, published in International Journal of Molecular Sciences
  • Treating late-onset Tay Sachs disease: Brain delivery with a dual trojan horse protein, 2024, published in Molecular Therapy - Methods & Clinical Development
  • Amyloid Precursor Protein and Tau Peptides Linked Together Ameliorate Loss of Cognition in an Alzheimer's Disease Animal Model, 2023, published in International Journal of Molecular Sciences

Their main research topics encompass:

  • Alzheimer's disease research and treatments
  • Cholinesterase and Neurodegenerative Diseases
  • Nuclear Receptors and Signaling
  • Lysosomal Storage Disorders Research
  • Autism Spectrum Disorder Research
  • RNA regulation and disease
  • Supramolecular Self-Assembly in Materials

Meir Wilchek has co-authored frequently with researchers such as Ruth Maron, Michael Tsoory, Ruth Arnon, Gad Armony, and Dan Frenkel.

Their publications appear notably in the International Journal of Molecular Sciences and Molecular Therapy - Methods & Clinical Development, reflecting focused contributions to molecular and clinical therapeutic research domains.

They have been recognized with memberships in significant scientific organizations, including the National Academy of Medicine (NAM) since 1993 and the European Molecular Biology Organization (EMBO).

Best Publications

  • Selective enzyme purification by affinity chromatography

    Pedro Cuatrecasas;Meir Wilchek;Christian B. Anfinsen

  • The avidin-biotin complex in bioanalytical applications

    Meir Wilchek;Edward A. Bayer

  • Introduction to avidin-biotin technology.

    Meir Wilchek;Edward A. Bayer

  • Three-dimensional structures of avidin and the avidin-biotin complex

    Oded Livnah;Edward A. Bayer;Meir Wilchek;Joel L. Sussman

  • The use of the avidin-biotin complex as a tool in molecular biology

    Edward A. Bayer;Meir Wilchek

  • A 25-kD inhibitor of actin polymerization is a low molecular mass heat shock protein.

    Talia Miron;Katia Vancompernolle;Joël Vandekerckhove;Meir Wilchek

  • THE MODE OF ACTION OF ALLICIN: TRAPPING OF RADICALS AND INTERACTION WITH THIOL CONTAINING PROTEINS

    Aharon Rabinkov;Talia Miron;Leonid Konstantinovski;Meir Wilchek

  • The mode of action of allicin: its ready permeability through phospholipid membranes may contribute to its biological activity.

    Talia Miron;Aharon Rabinkov;David Mirelman;Meir Wilchek

  • The Covalent Binding of Daunomycin and Adriamycin to Antibodies, with Retention of Both Drug and Antibody Activities

    Esther Hurwitz;Ronald Levy;Ruth Maron;Meir Wilchek

  • [14] Protein biotinylation

    Edward A. Bayer;Meir Wilchek

  • Distribution of end-to-end distances of oligopeptides in solution as estimated by energy transfer

    Elisha Haas;Meir Wilchek;Ephraim Katchalski-Katzir;Izchak Z. Steinberg

  • The avidin-biotin complex in affinity cytochemistry.

    Edward A. Bayer;Ehud Skutelsky;Meir Wilchek

  • Effect of purified allicin, the major ingredient of freshly crushed garlic, on cancer cell proliferation

    Keren Hirsch;Michael Danilenko;Judith Giat;Talia Miron

  • The avidin-biotin complex in immunology

    Meir Wilchek;Edward A Bayer

  • Essentials of biorecognition: the (strept)avidin-biotin system as a model for protein-protein and protein-ligand interaction.

    Meir Wilchek;Edward A. Bayer;Oded Livnah

  • A new approach (cyano-transfer) for cyanogen bromide activation of Sepharose at neutral pH, which yields activated resins, free of interfering nitrogen derivatives.

    Joachim Kohn;Meir Wilchek

  • Allicin from garlic strongly inhibits cysteine proteinases and cytopathic effects of Entamoeba histolytica.

    Serge Ankri;Talia Miron;Aharon Rabinkov;Meir Wilchek

  • The use of carbodiimides in the preparation of immunizing conjugates.

    Sara Bauminger;Meir Wilchek

  • [1] Affinity chromatography

    Meir Wilchek;Talia Miron;Joachim Kohn

  • Covalent coupling of nucleotides to agarose for affinity chromatography.

    Raphael Lamed;Yehuda Levin;Meir Wilchek

Frequent Co-Authors

Edward A. Bayer
Edward A. Bayer Weizmann Institute of Science
David Mirelman
David Mirelman Weizmann Institute of Science
Ruth Arnon
Ruth Arnon Weizmann Institute of Science
Markku S. Kulomaa
Markku S. Kulomaa Tampere University
Michael Sela
Michael Sela Weizmann Institute of Science
David Givol
David Givol Weizmann Institute of Science
Lev Weiner
Lev Weiner Weizmann Institute of Science
Ronen Alon
Ronen Alon Weizmann Institute of Science
Sarah Spiegel
Sarah Spiegel Virginia Commonwealth University

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