Matthias Gaestel

Overview

Best Publications

• Guidelines for the use and interpretation of assays for monitoring autophagy

  Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  8665
  Citations

• Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

  Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  8488
  Citations

• Small heat shock proteins are molecular chaperones

  U Jakob;M Gaestel;K Engel;J Buchner

  1715
  Citations

• Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation

  Monika Ehrnsperger;Simone Gräber;Matthias Gaestel;Johannes Buchner

  1135
  Citations

• Regulation of Hsp27 Oligomerization, Chaperone Function, and Protective Activity against Oxidative Stress/Tumor Necrosis Factor α by Phosphorylation

  Thorsten Rogalla;Monika Ehrnsperger;Xavier Preville;Alexey Kotlyarov

  1050
  Citations

• MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis.

  Alexey Kotlyarov;Armin Neininger;Carola Schubert;Rolf Eckert

  1009
  Citations

• The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism

  Reinhard Winzen;Michael Kracht;Birgit Ritter;Arno Wilhelm

  998
  Citations

• Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

  Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  895
  Citations

• TNF and increased intracellular iron alter macrophage polarization to a detrimental M1 phenotype in the injured spinal cord.

  Antje Kroner;Andrew D. Greenhalgh;Juan G. Zarruk;Rosmarini Passos dos Santos

  707
  Citations

• Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins

  David Stokoe;Katrin Engel;David G. Campbell;Philip Cohen

  698
  Citations

• MAPKAP kinases — MKs — two's company, three's a crowd

  Matthias Gaestel

  560
  Citations

• Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element.

  Edward Hitti;Tatiana Iakovleva;Matthew Brook;Stefanie Deppenmeier

  544
  Citations

• MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels.

  Armin Neininger;Dimitris Kontoyiannis;Alexey Kotlyarov;Reinhard Winzen

  505
  Citations

• Targeting innate immunity protein kinase signalling in inflammation.

  Matthias Gaestel;Alexey Kotlyarov;Michael Kracht

  446
  Citations

• Leptomycin B‐sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation

  Katrin Engel;Alexey Kotlyarov;Matthias Gaestel

  390
  Citations

• Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway.

  Pavel Kovarik;Dagmar Stoiber;Patrick A. Eyers;Rossella Menghini

  345
  Citations

• Distinct Cellular Functions of MK2

  Alexey Kotlyarov;Yvonne Yannoni;Susann Fritz;Kathrin Laass

  332
  Citations

• Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease.

  Dimitris Kontoyiannis;George Boulougouris;Menelaos Manoloukos;Maria Armaka

  323
  Citations

• Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology

  Dimitris Kontoyiannis;Alexey Kotlyarov;Ester Carballo;Lena Alexopoulou

  321
  Citations

• CREB is activated by UVC through a p38/HOG‐1‐dependent protein kinase

  M. Iordanov;K. Bender;T. Ade;W. Schmid

  297
  Citations