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D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
12744
World Ranking
12510
National Ranking
464

Overview

André-Patrick Arrigo is affiliated with Claude Bernard University Lyon 1 in France. Their research spans primarily the fields of Biochemistry, Genetics and Molecular Biology, with additional contributions to Medicine.

Their work focuses on several key subfields including Molecular Biology, Genetics, Infectious Diseases, Hematology, and Biotechnology. These areas intersect with a diverse range of scientific topics such as Hedgehog Signaling Pathway Studies, Ocular Disorders and Treatments, Developmental Biology and Gene Regulation, Heat shock proteins research, Viral gastroenteritis research and epidemiology, Iron Metabolism and Disorders, and Cancer Research and Treatments.

Frequent coauthors in André-Patrick Arrigo's research include Pierre-Antoine Bissey, Pauline Mathot, Catherine Guix, Mélissa Jasmin, and Isabelle Goddard.

The scientist has published in several respected journals, with frequent contributions to the following publication venues:

  • Cancer Research
  • International Journal of Molecular Sciences
  • European Journal of Cancer

Among the recent papers authored or co-authored by André-Patrick Arrigo are:

  • Blocking SHH/Patched Interaction Triggers Tumor Growth Inhibition through Patched-Induced Apoptosis (2020, Cancer Research)
  • Small Hsps as Therapeutic Targets of Cystic Fibrosis Transmembrane Conductance Regulator Protein (2021, International Journal of Molecular Sciences)
  • 130 (PB118): Efficacy of Quaratusugene Ozeplasmid TUSC2 Gene Therapy in Glioblastoma (2024, European Journal of Cancer)

Best Publications

  • Hsp27 negatively regulates cell death by interacting with cytochrome c

    Jean-Marie Bruey;Cécile Ducasse;Philippe Bonniaud;Luigi Ravagnan

  • Regulation of Hsp27 Oligomerization, Chaperone Function, and Protective Activity against Oxidative Stress/Tumor Necrosis Factor α by Phosphorylation

    Thorsten Rogalla;Monika Ehrnsperger;Xavier Preville;Alexey Kotlyarov

  • Human hsp27, Drosophila hsp27 and human alphaB-crystallin expression-mediated increase in glutathione is essential for the protective activity of these proteins against TNFalpha-induced cell death

    P Mehlen;C Kretz-Remy;X Préville;A P Arrigo

  • Small Stress Proteins as Novel Regulators of Apoptosis HEAT SHOCK PROTEIN 27 BLOCKs FAS/APO-1- AND STAUROSPORINE-INDUCED CELL DEATH

    Patrick Mehlen;Klaus Schulze-Osthoff;André-Patrick Arrigo

  • Gene expression and the thiol redox state

    André-Patrick Arrigo

  • Hsp27 as a negative regulator of cytochrome C release.

    Catherine Paul;Florence Manero;Sandrine Gonin;Carole Kretz-Remy

  • Actin cytoskeleton and small heat shock proteins: how do they interact?

    Nicole Mounier;André-Patrick Arrigo

  • Constitutive expression of human hsp27, Drosophila hsp27, or human alpha B-crystallin confers resistance to TNF- and oxidative stress-induced cytotoxicity in stably transfected murine L929 fibroblasts.

    P Mehlen;X Preville;P Chareyron;J Briolay

  • Mammalian small stress proteins protect against oxidative stress through their ability to increase glucose-6-phosphate dehydrogenase activity and by maintaining optimal cellular detoxifying machinery.

    Xavier Préville;Francesca Salvemini;Stéphane Giraud;Sylvain Chaufour

  • Small stress proteins: chaperones that act as regulators of intracellular redox state and programmed cell death

    Arrigo Ap

  • Inhibition of I kappa B-alpha phosphorylation and degradation and subsequent NF-kappa B activation by glutathione peroxidase overexpression.

    C Kretz-Remy;P Mehlen;M E Mirault;A P Arrigo

  • HSP27 as a Mediator of Confluence-dependent Resistance to Cell Death Induced by Anticancer Drugs

    Carmen Garrido;Patrick Ottavi;Annie Fromentin;Arlette Hammann

  • hsp27 as a Switch between Differentiation and Apoptosis in Murine Embryonic Stem Cells

    Patrick Mehlen;Anne Mehlen;Jacqueline Godet;André-Patrick Arrigo

  • Hsp27 consolidates intracellular redox homeostasis by upholding glutathione in its reduced form and by decreasing iron intracellular levels.

    André-Patrick Arrigo;Sophie Virot;Sylvain Chaufour;Wance Firdaus

  • Large unphosphorylated aggregates as the active form of hsp27 which controls intracellular reactive oxygen species and glutathione levels and generates a protection against TNFalpha in NIH-3T3-ras cells.

    Patrick Mehlen;Eilen Hickey;Lee A. Weber;André-Patrick Arrigo

  • The Effect of Heat Shock on Gene Expression in Drosophila melanogaster

    M E Mirault;M Goldschmidt-Clermont;L Moran;A P Arrigo

  • The role of heat shock proteins Hsp70 and Hsp27 in cellular protection of the central nervous system.

    Franklin Tb;Krueger-Naug Am;Clarke Db;Arrigo Ap

  • Heat Shock Protein 27 Enhances the Tumorigenicity of Immunogenic Rat Colon Carcinoma Cell Clones

    Carmen Garrido;Annie Fromentin;Bernard Bonnotte;Nathalie Favre

  • Hsp27 protects mitochondria of thermotolerant cells against apoptotic stimuli

    Afshin Samali;John D. Robertson;Elisabeth Peterson;Florence Manero

  • Hsp27: novel regulator of intracellular redox state.

    André-Patrick Arrigo

Frequent Co-Authors

Patrick Mehlen
Patrick Mehlen UniCancer Group
Carmen Garrido
Carmen Garrido University of Burgundy
Eric Solary
Eric Solary Institut Gustave Roussy
Matthias Gaestel
Matthias Gaestel Hannover Medical School
Loïc J. Blum
Loïc J. Blum Claude Bernard University Lyon 1
Robert M. Tanguay
Robert M. Tanguay Université Laval
Bernd Epe
Bernd Epe Johannes Gutenberg University of Mainz
Afshin Samali
Afshin Samali University of Galway
Patrice Codogno
Patrice Codogno Université Paris Cité
Klaus Schulze-Osthoff
Klaus Schulze-Osthoff University of Tübingen

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