Tony E. Hugli

Overview

Best Publications

• Complement activation during cardiopulmonary bypass. Evidence for generation of C3a and C5a anaphylatoxins

  Dennis E. Chenoweth;Steven W. Cooper;Tony E. Hugli;Robert W. Stewart

  1457
  Citations

• Chemotactic response to human C3a and C5a anaphylatoxins. I. Evaluation of C3a and C5a leukotaxis in vitro and under stimulated in vivo conditions.

  Horacio N. Fernandez;Peter M. Henson;Arthur Otani;Tony E. Hugli

  778
  Citations

• Demonstration of specific C5a receptor on intact human polymorphonuclear leukocytes.

  Dennis E. Chenoweth;Tony E. Hugli

  704
  Citations

• C3a is a chemotaxin for human eosinophils but not for neutrophils. I. C3a stimulation of neutrophils is secondary to eosinophil activation.

  Pamela J. Daffern;Philippe H. Pfeifer;Julia A. Ember;Tony E. Hugli

  374
  Citations

• Requirement and role of C5a in acute lung inflammatory injury in rats.

  Michael S. Mulligan;Elisabeth Schmid;Elisabeth Schmid;Beatrice Beck-Schimmer;Beatrice Beck-Schimmer;Gerd O. Till

  313
  Citations

• The alternative pathway C3/C5 convertase: chemical basis of factor B activation

  Philippe H. Lesavre;Tony E. Hugli;Alfred F. Esser;Hans J. Müller-Eberhard

  255
  Citations

• Partial Characterization of Human C5a Anaphylatoxin I. Chemical Description of the Carbohydrate and Polypeptide Portions of Human C5a

  Horacio N. Fernandez;Tony E. Hugli

  242
  Citations

• Examination of several potential mechanisms for the negative outcome in a clinical stroke trial of enlimomab, a murine anti-human intercellular adhesion molecule-1 antibody: a bedside-to-bench study.

  Kazuhide Furuya;Hidetaka Takeda;Salman Azhar;Richard M. McCarron

  233
  Citations

• Cytokine, complement, and endotoxin profiles associated with the development of the adult respiratory distress syndrome after severe injury.

  Thomas Donnelly;Peter Meade;Mark Jagels;H. Cryer

  228
  Citations

• Neuronal Expression of a Functional Receptor for the C5a Complement Activation Fragment

  Stephen A. O’Barr;Jody Caguioa;Donna Gruol;Guy Perkins

  221
  Citations

• Complement factors and their receptors

  Julia A. Ember;Tony E. Hugli

  221
  Citations

• Nucleotide sequence of cDNA and derived amino acid sequence of human complement component C9.

  Richard G. Discipio;Michael R. Gehring;Eckhard R. Podack;Chen Chen Kan

  213
  Citations

• Induction of interleukin-8 synthesis from monocytes by human C5a anaphylatoxin.

  Julia A. Ember;Sam D. Sanderson;Tony E. Hugli;Edward L. Morgan

  212
  Citations

• Structural Changes Accompanying Enzymatic Activation of Human Hageman Factor

  Susan D. Revak;Charles G. Cochrane;Alan R. Johnston;Tony E. Hugli

  202
  Citations

• C4a: the third anaphylatoxin of the human complement system.

  Jeffrey P. Gorski;Tony E. Hugli;Hans J. Muller-Eberhard

  201
  Citations

• Characterization of Complement Anaphylatoxins and Their Biological Responses

  Julia Ember;Mark Jagels;Tony Hugli

  195
  Citations

• Association of urinary leukotriene E4 excretion during aspirin challenges with severity of respiratory responses.

  Pamela J. Daffern;Diego Muilenburg;Tony E. Hugli;Donald D. Stevenson

  178
  Citations

• Arachidonate metabolism by human polymorphonuclear leukocytes stimulated by N-formyl-Met-Leu-Phe or complement component C5a is independent of phospholipase activation

  Robert M. Clancy;Clemens A. Dahinden;Tony E. Hugli

  174
  Citations

• The activation of human complement component C5 by a fluid phase C5 convertase.

  R G DiScipio;C A Smith;H J Muller-Eberhard;T E Hugli

  166
  Citations

• Role of cell surface contact in the kinetics of superoxide production by granulocytes.

  Clemens A. Dahinden;Jorg Fehr;Tony E. Hugli

  164
  Citations