World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
76
Citations
19480
World Ranking
1922
National Ranking
133

Medicine

D-Index
76
Citations
19504
World Ranking
18847
National Ranking
991

Overview

Jörg Köhl is affiliated with the University of Lübeck in Germany and focuses on research at the intersection of medicine, immunology, and microbiology. The main fields of study in their work include Medicine with 99 publications and Immunology and Microbiology with 39 publications. More specifically, their research spans subfields such as Immunology, Physiology, Genetics, Pathology and Forensic Medicine, and Neurology.

The scientific topics covered in Jörg Köhl's publications concentrate on the complement system and its role in diseases. Key topics include the complement system in diseases, coagulation, bradykinin, polyphosphates, angioedema, autoimmune bullous skin diseases, urticaria and related conditions, asthma and respiratory diseases, platelet disorders and treatments, and neuroinflammation and neurodegeneration mechanisms.

Among the recent papers authored or co-authored by Jörg Köhl are:

  • Endothelial C3a receptor mediates vascular inflammation and blood-brain barrier permeability during aging (2020) published in Journal of Clinical Investigation
  • The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts (2021) published in Immunity
  • Autoimmune pre-disease (2022) published in Autoimmunity Reviews
  • C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection (2023) published in Cell
  • Tackling COVID-19 infection through complement-targeted immunotherapy (2020) published in British Journal of Pharmacology

Jörg Köhl frequently collaborates with several researchers, including:

  • Christian M. Karsten (13 joint publications)
  • Ralf J. Ludwig (10 joint publications)
  • Katja Bieber (9 joint publications)
  • Christian D. Sadik (8 joint publications)
  • Enno Schmidt (7 joint publications)

Their work has been published repeatedly in the following venues:

  • Frontiers in Immunology (9 publications)
  • Immunobiology (8 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (4 publications)
  • British Journal of Pharmacology (3 publications)
  • Journal of Investigative Dermatology (3 publications)

Best Publications

  • The role of the anaphylatoxins in health and disease.

    Andreas Klos;Andrea J. Tenner;Kay-Ole Johswich;Rahasson R. Ager

  • Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation

    Tom Eirik Mollnes;Ole-Lars Brekke;Michael Fung;Hilde Fure

  • CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function

    Ian P. Lewkowich;Nancy S. Herman;Kathleen W. Schleifer;Matthew P. Dance

  • Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1

    Christian M. Karsten;Manoj K. Pandey;Julia Figge;Regina Kilchenstein

  • T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells

    Giuseppina Arbore;Erin E. West;Rosanne Spolski;Avril A. B. Robertson

  • Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma.

    Christopher L. Karp;Andrew Grupe;Eric Schadt;Susan L. Ewart

  • Functional roles for C5a receptors in sepsis

    Daniel Rittirsch;Michael A Flierl;Brian A Nadeau;Danielle E Day

  • C3a and C5a Stimulate Chemotaxis of Human Mast Cells

    Karin Hartmann;Beate M. Henz;Beate M. Henz;Sabine Krüger-Krasagakes;Sabine Krüger-Krasagakes;Jörg Köhl;Jörg Köhl

  • C3a modulates IL-1β secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 inflammasome activation

    Elham Asgari;Gaelle Le Friec;Hidekazu Yamamoto;Esperanza Perucha

  • Complement factor 5 is a quantitative trait gene that modifies liver fibrogenesis in mice and humans

    Sonja Hillebrandt;Sonja Hillebrandt;Hermann E Wasmuth;Ralf Weiskirchen;Claus Hellerbrand

  • Discrimination of sepsis and systemic inflammatory response syndrome by determination of circulating plasma concentrations of procalcitonin, protein complement 3a, and interleukin-6.

    Oliver Selberg;Hartmut Hecker;Michael Martin;Andreas Klos

  • A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma

    Jörg Köhl;Ralf Baelder;Ian P. Lewkowich;Manoj K. Pandey

  • Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate’s protective effect in EAE

    Hui Chen;Julian C. Assmann;Antje Krenz;Mahbubur Rahman

  • C5a negatively regulates toll-like receptor 4-induced immune responses.

    Heiko Hawlisch;Yasmine Belkaid;Ralf Baelder;David Hildeman

  • Complement Factor C5a Mediates Renal Ischemia-Reperfusion Injury Independent from Neutrophils

    Bart de Vries;Jörg Köhl;Wouter K. G. Leclercq;Tim G. A. M. Wolfs

  • Staphylococcal complement evasion by various convertase-blocking molecules

    Ilse Jongerius;Jörg Köhl;Manoj K. Pandey;Maartje Ruyken

  • Complement factors C3a and C5a are increased in bronchoalveolar lavage fluid after segmental allergen provocation in subjects with asthma.

    Norbert Krug;Thomas Tschernig;Veit J. Erpenbeck;Jens M. Hohlfeld

  • Anaphylatoxins and infectious and non-infectious inflammatory diseases.

    Jörg Köhl

  • Expression cloning of the human C3a anaphylatoxin receptor (C3aR) from differentiated U-937 cells

    Torsten Crass;Ute Raffetseder;Ulrich Martin;Melanie Grove

  • Selection of a C5a receptor antagonist from phage libraries attenuating the inflammatory response in immune complex disease and ischemia/reperfusion injury.

    T Heller;M Hennecke;U Baumann;J E Gessner

Frequent Co-Authors

Andreas Klos
Andreas Klos Hannover Medical School
Ralf Ludwig
Ralf Ludwig University of Rostock
Detlef Zillikens
Detlef Zillikens University of Lübeck
Marsha Wills-Karp
Marsha Wills-Karp Johns Hopkins University
Claudia Kemper
Claudia Kemper National Institutes of Health
Rudolf A. Manz
Rudolf A. Manz University of Lübeck
Markus Huber-Lang
Markus Huber-Lang University of Ulm
John D. Lambris
John D. Lambris University of Pennsylvania
Fred D. Finkelman
Fred D. Finkelman University of Cincinnati
Ulrich Martin
Ulrich Martin Hannover Medical School

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