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Medicine

D-Index
102
Citations
46354
World Ranking
7560
National Ranking
3941

Overview

Harald Jüppner is affiliated with Harvard University in the United States. Their research primarily spans the fields of biochemistry, genetics, molecular biology, and medicine, with a specific focus on genetics, molecular biology, oncology, nephrology, and pathology and forensic medicine.

Their work encompasses several main topics including genetic syndromes and imprinting, bone health and treatments, parathyroid disorders and treatments, fibroblast growth factor research, genomics and rare diseases, congenital heart defects research, and epigenetics and DNA methylation.

Jüppner has published research in several scientific venues, with recurrent contributions to:

  • Journal of the American Society of Nephrology
  • JBMR Plus
  • The Journal of Clinical Endocrinology & Metabolism
  • JCI Insight
  • Journal of Clinical Investigation

Notable recent papers include:

  • "Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney" (2020, Journal of Clinical Investigation)
  • "Recommendations for Diagnosis and Treatment of Pseudohypoparathyroidism and Related Disorders: An Updated Practical Tool for Physicians and Patients" (2020, Hormone Research in Paediatrics)
  • "Kidney glycolysis serves as a mammalian phosphate sensor that maintains phosphate homeostasis" (2023, Journal of Clinical Investigation)
  • "Targeted Long-Read Sequencing Identifies a Retrotransposon Insertion as a Cause of Altered GNAS Exon A/B Methylation in a Family With Autosomal Dominant Pseudohypoparathyroidism Type 1b (PHP1B)" (2020, Journal of Bone and Mineral Research)
  • "Nephropathic Cystinosis: A Distinct Form of CKD-Mineral and Bone Disorder that Provides Novel Insights into the Regulation of FGF23" (2020, Journal of the American Society of Nephrology)

Their research collaboration includes frequent coauthors such as Monica Reyes, Patrick Hanna, Thomas J. Gardella, Murat Bastepe, and Agnès Linglart, reflecting a multidisciplinary approach within their fields of study.

Best Publications

  • LDL Receptor-Related Protein 5 (LRP5) Affects Bone Accrual and Eye Development

    Y. Q. Gong;R. B. Slee;N. Fukai;G. Rawadi

  • Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis.

    Orlando M. Gutiérrez;Michael Mannstadt;Tamara Isakova;Jose Alejandro Rauh-Hain

  • A novel cyclin encoded by a bcl1 -linked candidate oncogene

    Toru Motokura;Theodora Bloom;Hyung Goo Kim;Harald Jüppner.

  • A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide

    Harald Jüppner;Abdul Badi Abou-Samra;Mason Freeman;Xiang F. Kong

  • Primer on the metabolic bone diseases and disorders of mineral metabolism

    John P. Bilezikian;Roger Bouillon;Thomas Clemens;Juliet Compston

  • PTH/PTHrP Receptor in Early Development and Indian Hedgehog--Regulated Bone Growth

    Beate Lanske;Andrew C. Karaplis;Kaechong Lee;Arne Luz

  • Fibroblast Growth Factor-23 Mitigates Hyperphosphatemia but Accentuates Calcitriol Deficiency in Chronic Kidney Disease

    Orlando Gutierrez;Tamara Isakova;Eugene Rhee;Anand Shah

  • Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium

    A B Abou-Samra;H Jüppner;T Force;M W Freeman

  • Circulating concentration of FGF-23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy volunteers.

    Tobias Larsson;U.L.F. Nisbeth;Östen Ljunggren;Harald Jüppner

  • Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia.

    Kenneth B Jonsson;Richard Zahradnik;Tobias Larsson;Kenneth E White

  • Regulation of phosphate homeostasis by PTH, vitamin D, and FGF23.

    Clemens Bergwitz;Harald Jüppner

  • A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia.

    Ernestina Schipani;Klaus Kruse;Harald Jüppner

  • Transgenic Mice Expressing Fibroblast Growth Factor 23 under the Control of the α1(I) Collagen Promoter Exhibit Growth Retardation, Osteomalacia, and Disturbed Phosphate Homeostasis

    Tobias Larsson;Richard Marsell;Ernestina Schipani;Claes Ohlsson

  • Hypoparathyroidism in the adult: Epidemiology, diagnosis, pathophysiology, target‐organ involvement, treatment, and challenges for future research

    John P Bilezikian;Aliya Khan;John T Potts;Maria Luisa Brandi

  • SLC34A3 Mutations in Patients with Hereditary Hypophosphatemic Rickets with Hypercalciuria Predict a Key Role for the Sodium-Phosphate Cotransporter NaPi-IIc in Maintaining Phosphate Homeostasis

    Clemens Bergwitz;Nicole M. Roslin;Martin Tieder;J.C. Loredo-Osti

  • Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice.

    Despina Sitara;Mohammed S. Razzaque;Martina Hesse;Subbiah Yoganathan

  • DMP1 mutations in autosomal recessive hypophosphatemia implicate a bone matrix protein in the regulation of phosphate homeostasis

    Bettina Lorenz-Depiereux;Murat Bastepe;Anna Benet-Pagès;Mustapha Amyere

  • Mutations in the Tight-Junction Gene Claudin 19 (CLDN19) Are Associated with Renal Magnesium Wasting, Renal Failure, and Severe Ocular Involvement

    Martin Konrad;André Schaller;Dominik Seelow;Amit V. Pandey

  • Regulation of C-Terminal and Intact FGF-23 by Dietary Phosphate in Men and Women†

    Sherri Ann M Burnett;Samantha C Gunawardene;F Richard Bringhurst;Harald Jüppner

  • Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide

    E. Schipani;B. Lanske;J. Hunzelman;A. Luz

Frequent Co-Authors

Gino V. Segre
Gino V. Segre Harvard University
Thomas J. Gardella
Thomas J. Gardella Harvard University
John T. Potts
John T. Potts Harvard University
Henry M. Kronenberg
Henry M. Kronenberg Harvard University
Ernestina Schipani
Ernestina Schipani University of Michigan–Ann Arbor
Myles Wolf
Myles Wolf Duke University
David T. Rubin
David T. Rubin University of Chicago
Beate Lanske
Beate Lanske Harvard University
Robert Elashoff
Robert Elashoff University of California, Los Angeles
Rajesh V. Thakker
Rajesh V. Thakker University of Oxford

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