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Biology and Biochemistry

D-Index
74
Citations
26568
World Ranking
5481
National Ranking
2603

Medicine

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74
Citations
26573
World Ranking
19307
National Ranking
9620

Overview

Ernestina Schipani is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily focuses on the intersection of biochemistry, genetics, and molecular biology, with a significant body of work also related to medicine. Schipani's research spans a range of subfields including molecular biology, cancer research, genetics, oncology, and immunology.

The main topics of their work cover areas such as cancer, hypoxia, and metabolism; bone metabolism and diseases; bone health and treatments; high altitude and hypoxia; erythropoietin and anemia treatment; adipose tissue and metabolism; and eicosanoids and hypertension pharmacology.

Schipani has published multiple papers, including recent works such as:

  • The role of HIF proteins in maintaining the metabolic health of the intervertebral disc, 2021, Nature Reviews Rheumatology
  • Systemic Administration of Recombinant Irisin Accelerates Fracture Healing in Mice, 2021, International Journal of Molecular Sciences
  • Oxidative phosphorylation in bone cells, 2023, Bone Reports
  • Irisin Modulates Inflammatory, Angiogenic, and Osteogenic Factors during Fracture Healing, 2023, International Journal of Molecular Sciences
  • ERα Signaling in GHRH/Kiss1 Dual-Phenotype Neurons Plays Sex-Specific Roles in Growth and Puberty, 2020, Journal of Neuroscience

They have collaborated frequently with several coauthors, including Mohd Parvez Khan, Elena Sabini, Giulia Lanzolla, Christophe Merceron, and Zachary Tata.

Ernestina Schipani's work has appeared repeatedly in various scientific journals, with notable frequent publications in JBMR Plus, Proceedings of the National Academy of Sciences, International Journal of Molecular Sciences, Bone Reports, and Bone.

Best Publications

  • Osteoblastic cells regulate the haematopoietic stem cell niche

    Laura M Calvi;Gregor B Adams;K. W. Weibrecht;Jonathan Weber

  • A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide

    Harald Jüppner;Abdul Badi Abou-Samra;Mason Freeman;Xiang F. Kong

  • Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium

    A B Abou-Samra;H Jüppner;T Force;M W Freeman

  • Hypoxia in cartilage: HIF-1α is essential for chondrocyte growth arrest and survival

    Ernestina Schipani;Heather E. Ryan;Susanna Didrickson;Tatsuya Kobayashi

  • The hypoxia-inducible factor α pathway couples angiogenesis to osteogenesis during skeletal development

    Ying Wang;Chao Wan;Lianfu Deng;Ximeng Liu

  • A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia.

    Ernestina Schipani;Klaus Kruse;Harald Jüppner

  • Transgenic Mice Expressing Fibroblast Growth Factor 23 under the Control of the α1(I) Collagen Promoter Exhibit Growth Retardation, Osteomalacia, and Disturbed Phosphate Homeostasis

    Tobias Larsson;Richard Marsell;Ernestina Schipani;Claes Ohlsson

  • Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone related-protein-dependent and -independent pathways.

    Seth J. Karp;Ernestina Schipani;Benoit St-Jacques;Joy Hunzelman

  • Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide

    E. Schipani;B. Lanske;J. Hunzelman;A. Luz

  • Molecular mechanisms of endochondral bone development

    Sylvain Provot;Ernestina Schipani

  • VEGFA is necessary for chondrocyte survival during bone development.

    Elazar Zelzer;Roni Mamluk;Napoleone Ferrara;Randall S. Johnson

  • Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development

    Ung Il Chung;Ernestina Schipani;Andrew P. McMahon;Henry M. Kronenberg

  • Regulation of osteogenesis-angiogenesis coupling by HIFs and VEGF.

    Ernestina Schipani;Christa Maes;Geert Carmeliet;Gregg L Semenza

  • Control of Bone Mass and Remodeling by PTH Receptor Signaling in Osteocytes

    Charles A O'Brien;Lilian I. Plotkin;Carlo Galli;Joseph J. Goellner

  • Activated parathyroid hormone/parathyroid hormone–related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone

    L.M. Calvi;N.A. Sims;J.L. Hunzelman;M.C. Knight

  • Dicer-dependent pathways regulate chondrocyte proliferation and differentiation

    Tatsuya Kobayashi;Jun Lu;Bradley S. Cobb;Stephen J. Rodda

  • PTHrP and Indian hedgehog control differentiation of growth plate chondrocytes at multiple steps.

    Tatsuya Kobayashi;Ung Il Chung;Ernestina Schipani;Michael Starbuck

  • The HIF Signaling Pathway in Osteoblasts Directly Modulates Erythropoiesis through the Production of EPO

    Erinn B. Rankin;Colleen Wu;Richa Khatri;Tremika L.S. Wilson

  • Constitutively Activated Receptors for Parathyroid Hormone and Parathyroid Hormone–Related Peptide in Jansen's Metaphyseal Chondrodysplasia

    E. Schipani;Craig Langman;A. M. Parfitt;G. S. Jensen

  • HIF-1α controls extracellular matrix synthesis by epiphyseal chondrocytes

    David Pfander;Thorsten Cramer;Ernestina Schipani;Randall S. Johnson

Frequent Co-Authors

Henry M. Kronenberg
Henry M. Kronenberg Harvard University
Harald Jüppner
Harald Jüppner Harvard University
Amato J. Giaccia
Amato J. Giaccia Stanford University
Gino V. Segre
Gino V. Segre Harvard University
Randall S. Johnson
Randall S. Johnson University of Cambridge
John T. Potts
John T. Potts Harvard University
Thomas L. Clemens
Thomas L. Clemens United States Department of Veterans Affairs
Beate Lanske
Beate Lanske Harvard University
Mary L. Bouxsein
Mary L. Bouxsein Beth Israel Deaconess Medical Center
David T. Scadden
David T. Scadden Harvard University

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