Natalie A. Sims

Overview

Best Publications

• Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs

  Ingrid G. Winkler;Natalie A. Sims;Allison R. Pettit;Valérie Barbier

  929
  Citations

• Coupling the activities of bone formation and resorption: a multitude of signals within the basic multicellular unit

  Natalie A Sims;T John Martin

  803
  Citations

• Osteoclast-derived activity in the coupling of bone formation to resorption

  T. John Martin;Natalie A. Sims

  772
  Citations

• Bone remodeling: Multiple cellular interactions required for coupling of bone formation and resorption.

  Natalie A. Sims;Jonathan H. Gooi

  653
  Citations

• Rb Regulates Interactions between Hematopoietic Stem Cells and Their Bone Marrow Microenvironment

  Carl R. Walkley;Jeremy M. Shea;Natalie A. Sims;Louise E. Purton

  472
  Citations

• Activated parathyroid hormone/parathyroid hormone–related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone

  L.M. Calvi;N.A. Sims;J.L. Hunzelman;M.C. Knight

  402
  Citations

• Overexpression of DeltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis.

  G Sabatakos;N A Sims;J Chen;K Aoki

  399
  Citations

• Deletion of estrogen receptors reveals a regulatory role for estrogen receptors-β in bone remodeling in females but not in males

  N.A Sims;S Dupont;A Krust;P Clement-Lacroix

  395
  Citations

• The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

  Lauren S. Whyte;Erik Ryberg;Natalie A. Sims;Susan A. Ridge

  377
  Citations

• Model structure and control of bone remodeling: a theoretical study.

  Peter Pivonka;Jan Zimak;David W. Smith;Bruce S. Gardiner

  361
  Citations

• Decreased C-Src Expression Enhances Osteoblast Differentiation and Bone Formation

  Marilena Marzia;Natalie A. Sims;Susanne Voit;Silvia Migliaccio;Silvia Migliaccio

  331
  Citations

• Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice

  Maya Kansara;Michael Tsang;Laurent Kodjabachian;Natalie A. Sims

  327
  Citations

• Interleukin-6 modulates production of T lymphocyte-derived cytokines in antigen-induced arthritis and drives inflammation-induced osteoclastogenesis.

  Peter K K Wong;Julian M W Quinn;Natalie A Sims;Annemarie van Nieuwenhuijze

  326
  Citations

• Osteoprotegerin reduces osteoclast numbers and prevents bone erosion in collagen-induced arthritis.

  Evan Romas;Evan Romas;Natalie A Sims;Daphne K Hards;Mandy Lee Lindsay

  325
  Citations

• Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice

  Emma C. Walker;Narelle E. McGregor;Ingrid J. Poulton;Melissa Solano;Melissa Solano

  298
  Citations

• Quantifying the osteocyte network in the human skeleton

  Pascal R. Buenzli;Natalie A. Sims

  285
  Citations

• Bone homeostasis in growth hormone receptor–null mice is restored by IGF-I but independent of Stat5

  Natalie A. Sims;Philippe Clément-Lacroix;Francesca Da Ponte;Yasmina Bouali

  279
  Citations

• Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma

  David M. Thomas;Sandra A. Johnson;Natalie A. Sims;Melanie K. Trivett

  257
  Citations

• SOCS-3 negatively regulates innate and adaptive immune mechanisms in acute IL-1–dependent inflammatory arthritis

  Peter K.K. Wong;Paul J. Egan;Ben A. Croker;Kristy O’Donnell

  249
  Citations

• Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2−/− mice

  Hava Gil-Henn;Olivier Destaing;Natalie A. Sims;Kazuhiro Aoki;Kazuhiro Aoki

  247
  Citations