D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 70 Citations 16,024 257 World Ranking 4462 National Ranking 114

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Internal medicine
  • Cytokine

Osteoclast, Bone remodeling, Internal medicine, Endocrinology and Bone resorption are her primary areas of study. The various areas that Natalie A. Sims examines in her Osteoclast study include Osteoprotegerin, Bone cell, Arthritis, RANKL and Osteoblast. Her Osteoblast research includes elements of Leukemia inhibitory factor receptor, Oncostatin M, Cell biology, Sclerostin and Bone marrow.

Her research in Bone remodeling intersects with topics in Cortical bone, Pathology, Bone growth and Cannabinoid receptor. The study incorporates disciplines such as Cannabinoid, O-1602, Protein tyrosine phosphatase and c-Fos in addition to Endocrinology. Her Bone resorption study integrates concerns from other disciplines, such as Osteopetrosis, Osteocyte, Proto-oncogene tyrosine-protein kinase Src, Estrogen and Resorption.

Her most cited work include:

  • Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs (563 citations)
  • Osteoclast-derived activity in the coupling of bone formation to resorption (524 citations)
  • Coupling the activities of bone formation and resorption: a multitude of signals within the basic multicellular unit (413 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of study are Internal medicine, Endocrinology, Osteoblast, Cell biology and Osteoclast. The study of Internal medicine is intertwined with the study of Sclerostin in a number of ways. Her studies deal with areas such as Cortical bone, Receptor and Parathyroid hormone as well as Endocrinology.

Her Osteoblast study incorporates themes from Immunology, Bone marrow, Osteoid and Paracrine signalling. Her Cell biology research incorporates themes from Cellular differentiation and Leukemia inhibitory factor. Her Osteoclast research also works with subjects such as

  • Bone resorption, which have a strong connection to Resorption,
  • RANKL that intertwine with fields like Osteoprotegerin, Cancer research and Glycoprotein 130.

She most often published in these fields:

  • Internal medicine (62.89%)
  • Endocrinology (61.64%)
  • Osteoblast (48.74%)

What were the highlights of her more recent work (between 2018-2021)?

  • Cell biology (44.03%)
  • Osteoblast (48.74%)
  • Osteocyte (23.58%)

In recent papers she was focusing on the following fields of study:

Natalie A. Sims mainly focuses on Cell biology, Osteoblast, Osteocyte, Osteoclast and Cortical bone. Natalie A. Sims has included themes like Bone marrow, Osteoid, Mineralization and Leukemia inhibitory factor in her Cell biology study. Her research in Osteoblast intersects with topics in Paracrine signalling, Phenotype, Matrix, Bone growth and Bone remodeling.

Her Osteoclast research is multidisciplinary, incorporating elements of Bone mass, Cell type, Bone resorption and RANKL. Her studies in RANKL integrate themes in fields like Osteoprotegerin and Mesenchymal stem cell. Her Receptor research is multidisciplinary, relying on both Calcium metabolism, Endocrinology and Parathyroid hormone-related protein, Parathyroid hormone.

Between 2018 and 2021, her most popular works were:

  • Osteoclasts Provide Coupling Signals to Osteoblast Lineage Cells Through Multiple Mechanisms (30 citations)
  • IL-6 exhibits both cis- and trans-signaling in osteocytes and osteoblasts, but only trans-signaling promotes bone formation and osteoclastogenesis (21 citations)
  • IL-6 exhibits both cis- and trans-signaling in osteocytes and osteoblasts, but only trans-signaling promotes bone formation and osteoclastogenesis (21 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Cytokine

Her primary scientific interests are in Cell biology, Osteoblast, Bone growth, Osteocyte and SOCS3. Her Cell biology study frequently draws connections to other fields, such as Bone marrow. Her study in Osteoblast is interdisciplinary in nature, drawing from both Autophagy, Type I collagen, Endocrinology, Bone remodeling and Osteogenesis imperfecta.

Her research integrates issues of Cortical bone, Calcification and Mineralization in her study of Osteocyte. Her biological study spans a wide range of topics, including Osteoclast, Cytokine and Leukemia inhibitory factor. Her Osteoclast study combines topics from a wide range of disciplines, such as Physiology, Paracrine signalling and RANKL.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs

Ingrid G. Winkler;Natalie A. Sims;Allison R. Pettit;Valérie Barbier.
Blood (2010)

821 Citations

Osteoclast-derived activity in the coupling of bone formation to resorption

T. John Martin;Natalie A. Sims.
Trends in Molecular Medicine (2005)

737 Citations

Coupling the activities of bone formation and resorption: a multitude of signals within the basic multicellular unit

Natalie A Sims;T John Martin.
bonekey Reports (2014)

710 Citations

Bone remodeling: Multiple cellular interactions required for coupling of bone formation and resorption.

Natalie A. Sims;Jonathan H. Gooi.
Seminars in Cell & Developmental Biology (2008)

551 Citations

Rb Regulates Interactions between Hematopoietic Stem Cells and Their Bone Marrow Microenvironment

Carl R. Walkley;Jeremy M. Shea;Natalie A. Sims;Louise E. Purton.
Cell (2007)

437 Citations

Overexpression of DeltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis.

G Sabatakos;N A Sims;J Chen;K Aoki.
Nature Medicine (2000)

387 Citations

Deletion of estrogen receptors reveals a regulatory role for estrogen receptors-β in bone remodeling in females but not in males

N.A Sims;S Dupont;A Krust;P Clement-Lacroix.
Bone (2002)

382 Citations

Activated parathyroid hormone/parathyroid hormone–related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone

L.M. Calvi;N.A. Sims;J.L. Hunzelman;M.C. Knight.
Journal of Clinical Investigation (2001)

380 Citations

Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice

Maya Kansara;Michael Tsang;Laurent Kodjabachian;Natalie A. Sims.
Journal of Clinical Investigation (2009)

319 Citations

Model structure and control of bone remodeling: a theoretical study.

Peter Pivonka;Jan Zimak;David W. Smith;Bruce S. Gardiner.
Bone (2008)

319 Citations

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