D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 45 Citations 10,824 152 World Ranking 12924 National Ranking 367

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Immune system

His main research concerns Haematopoiesis, Bone marrow, Cell biology, Progenitor cell and Immunology. His Haematopoiesis study introduces a deeper knowledge of Stem cell. His Bone marrow study integrates concerns from other disciplines, such as Hematopoietic Stem Cell Mobilization, Granulocyte colony-stimulating factor, Endocrinology and Granulocyte.

His research integrates issues of Receptor, Integrin, Stromal cell and Osteoblast in his study of Cell biology. His work on Stem cell factor as part of general Progenitor cell research is often related to P-selectin, thus linking different fields of science. His work investigates the relationship between Immunology and topics such as Transplantation that intersect with problems in Chemotherapy regimen, Plerixafor and Intensive care medicine.

His most cited work include:

  • Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide. (682 citations)
  • Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs (563 citations)
  • Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor (445 citations)

What are the main themes of his work throughout his whole career to date?

Haematopoiesis, Bone marrow, Stem cell, Cell biology and Progenitor cell are his primary areas of study. His work deals with themes such as Molecular biology, Stromal cell, Immunology and Transplantation, which intersect with Haematopoiesis. Jean-Pierre Levesque combines subjects such as Cancer research, Granulocyte colony-stimulating factor, E-selectin, Granulocyte and Hematopoietic stem cell with his study of Bone marrow.

The concepts of his Stem cell study are interwoven with issues in Plerixafor, Mesenchymal stem cell, Pathology and Bone organ. His study in Cell biology is interdisciplinary in nature, drawing from both Niche, Integrin, Cell adhesion and Osteoblast. His studies deal with areas such as CD34, Macrophage colony-stimulating factor and Adult stem cell as well as Progenitor cell.

He most often published in these fields:

  • Haematopoiesis (48.37%)
  • Bone marrow (46.05%)
  • Stem cell (39.07%)

What were the highlights of his more recent work (between 2017-2021)?

  • Bone marrow (46.05%)
  • Cancer research (23.72%)
  • Haematopoiesis (48.37%)

In recent papers he was focusing on the following fields of study:

Jean-Pierre Levesque focuses on Bone marrow, Cancer research, Haematopoiesis, Stem cell and Cell biology. His Bone marrow study integrates concerns from other disciplines, such as Inflammation, Molecular biology, Erythropoiesis and Granulocyte colony-stimulating factor. Jean-Pierre Levesque has researched Cancer research in several fields, including Hematopoietic stem cell, Autologous transplantation, Chemotherapy and E-selectin.

Much of his study explores Haematopoiesis relationship to Progenitor cell. The Stem cell study combines topics in areas such as Mesenchymal stem cell and Transplantation. His work in Cell biology tackles topics such as Macrophage which are related to areas like Flow cytometry, Erythroblast, Cell type and Single-cell analysis.

Between 2017 and 2021, his most popular works were:

  • Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment (32 citations)
  • Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment (32 citations)
  • Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2 (27 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Immune system

Jean-Pierre Levesque spends much of his time researching Cancer research, Bone marrow, Haematopoiesis, Hematopoietic stem cell and Heterotopic ossification. Protein kinase B, Myeloid, E-selectin and Signal transduction is closely connected to Leukemia in his research, which is encompassed under the umbrella topic of Cancer research. His Bone marrow research incorporates elements of Granulocyte colony-stimulating factor and Granulocyte.

The study incorporates disciplines such as Progenitor cell and Plerixafor in addition to Haematopoiesis. His Hematopoietic stem cell research includes themes of Hematopoietic stem cell transplantation, Transplantation and Erythropoiesis. His work on Hematopoietic Stem Cell Mobilization as part of general Cell biology research is frequently linked to Procollagen-proline dioxygenase, Vascular endothelial growth factor A and Kinase insert domain receptor, thereby connecting diverse disciplines of science.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide.

Jean-Pierre Lévesque;Jean Hendy;Yasushi Takamatsu;Paul J. Simmons.
Journal of Clinical Investigation (2003)

892 Citations

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs

Ingrid G. Winkler;Natalie A. Sims;Allison R. Pettit;Valérie Barbier.
Blood (2010)

734 Citations

Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor

Jean Pierre Lévesque;Yasushi Takamatsu;Susan K. Nilsson;David N. Haylock.
Blood (2001)

694 Citations

G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow

Craig L. Semerad;Matthew J. Christopher;Fulu Liu;Brenton Short.
Blood (2005)

547 Citations

Cytokines increase human hemopoietic cell adhesiveness by activation of very late antigen (VLA)-4 and VLA-5 integrins.

J P Lévesque;D I Leavesley;S Niutta;M Vadas.
Journal of Experimental Medicine (1995)

350 Citations

Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance

Ingrid G Winkler;Valérie Barbier;Bianca Nowlan;Rebecca N Jacobsen.
Nature Medicine (2012)

350 Citations

Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment.

Jean Pierre Lévesque;Jean Hendy;Yasushi Takamatsu;Brenda Williams.
Experimental Hematology (2002)

322 Citations

Release of early human hematopoietic progenitors from quiescence by antisense transforming growth factor beta 1 or Rb oligonucleotides.

Jacques Hatzfeld;Ma-Lin Li;Eugene L. Brown;Hemchand Sookdeo.
Journal of Experimental Medicine (1991)

298 Citations

Characterization of hematopoietic progenitor mobilization in protease-deficient mice.

Jean Pierre Levesque;Fulu Liu;Paul J. Simmons;Tomoko Betsuyaku.
Blood (2004)

297 Citations

Molecular trafficking mechanisms of multipotent mesenchymal stem cells derived from human bone marrow and placenta.

Gary Brooke;Hui Tong;Jean-Pierre Levesque;Kerry Atkinson.
Stem Cells and Development (2008)

263 Citations

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