His main research concerns Haematopoiesis, Bone marrow, Cell biology, Progenitor cell and Immunology. His Haematopoiesis study introduces a deeper knowledge of Stem cell. His Bone marrow study integrates concerns from other disciplines, such as Hematopoietic Stem Cell Mobilization, Granulocyte colony-stimulating factor, Endocrinology and Granulocyte.
His research integrates issues of Receptor, Integrin, Stromal cell and Osteoblast in his study of Cell biology. His work on Stem cell factor as part of general Progenitor cell research is often related to P-selectin, thus linking different fields of science. His work investigates the relationship between Immunology and topics such as Transplantation that intersect with problems in Chemotherapy regimen, Plerixafor and Intensive care medicine.
Haematopoiesis, Bone marrow, Stem cell, Cell biology and Progenitor cell are his primary areas of study. His work deals with themes such as Molecular biology, Stromal cell, Immunology and Transplantation, which intersect with Haematopoiesis. Jean-Pierre Levesque combines subjects such as Cancer research, Granulocyte colony-stimulating factor, E-selectin, Granulocyte and Hematopoietic stem cell with his study of Bone marrow.
The concepts of his Stem cell study are interwoven with issues in Plerixafor, Mesenchymal stem cell, Pathology and Bone organ. His study in Cell biology is interdisciplinary in nature, drawing from both Niche, Integrin, Cell adhesion and Osteoblast. His studies deal with areas such as CD34, Macrophage colony-stimulating factor and Adult stem cell as well as Progenitor cell.
Jean-Pierre Levesque focuses on Bone marrow, Cancer research, Haematopoiesis, Stem cell and Cell biology. His Bone marrow study integrates concerns from other disciplines, such as Inflammation, Molecular biology, Erythropoiesis and Granulocyte colony-stimulating factor. Jean-Pierre Levesque has researched Cancer research in several fields, including Hematopoietic stem cell, Autologous transplantation, Chemotherapy and E-selectin.
Much of his study explores Haematopoiesis relationship to Progenitor cell. The Stem cell study combines topics in areas such as Mesenchymal stem cell and Transplantation. His work in Cell biology tackles topics such as Macrophage which are related to areas like Flow cytometry, Erythroblast, Cell type and Single-cell analysis.
Jean-Pierre Levesque spends much of his time researching Cancer research, Bone marrow, Haematopoiesis, Hematopoietic stem cell and Heterotopic ossification. Protein kinase B, Myeloid, E-selectin and Signal transduction is closely connected to Leukemia in his research, which is encompassed under the umbrella topic of Cancer research. His Bone marrow research incorporates elements of Granulocyte colony-stimulating factor and Granulocyte.
The study incorporates disciplines such as Progenitor cell and Plerixafor in addition to Haematopoiesis. His Hematopoietic stem cell research includes themes of Hematopoietic stem cell transplantation, Transplantation and Erythropoiesis. His work on Hematopoietic Stem Cell Mobilization as part of general Cell biology research is frequently linked to Procollagen-proline dioxygenase, Vascular endothelial growth factor A and Kinase insert domain receptor, thereby connecting diverse disciplines of science.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide.
Jean-Pierre Lévesque;Jean Hendy;Yasushi Takamatsu;Paul J. Simmons.
Journal of Clinical Investigation (2003)
Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs
Ingrid G. Winkler;Natalie A. Sims;Allison R. Pettit;Valérie Barbier.
Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor
Jean Pierre Lévesque;Yasushi Takamatsu;Susan K. Nilsson;David N. Haylock.
G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow
Craig L. Semerad;Matthew J. Christopher;Fulu Liu;Brenton Short.
Cytokines increase human hemopoietic cell adhesiveness by activation of very late antigen (VLA)-4 and VLA-5 integrins.
J P Lévesque;D I Leavesley;S Niutta;M Vadas.
Journal of Experimental Medicine (1995)
Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance
Ingrid G Winkler;Valérie Barbier;Bianca Nowlan;Rebecca N Jacobsen.
Nature Medicine (2012)
Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment.
Jean Pierre Lévesque;Jean Hendy;Yasushi Takamatsu;Brenda Williams.
Experimental Hematology (2002)
Release of early human hematopoietic progenitors from quiescence by antisense transforming growth factor beta 1 or Rb oligonucleotides.
Jacques Hatzfeld;Ma-Lin Li;Eugene L. Brown;Hemchand Sookdeo.
Journal of Experimental Medicine (1991)
Characterization of hematopoietic progenitor mobilization in protease-deficient mice.
Jean Pierre Levesque;Fulu Liu;Paul J. Simmons;Tomoko Betsuyaku.
Molecular trafficking mechanisms of multipotent mesenchymal stem cells derived from human bone marrow and placenta.
Gary Brooke;Hui Tong;Jean-Pierre Levesque;Kerry Atkinson.
Stem Cells and Development (2008)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: