Janina Ratajczak

Overview

Best Publications

• Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery.

  J Ratajczak;K Miekus;M Kucia;J Zhang

  1812
  Citations

• Membrane-derived microvesicles: important and underappreciated mediators of cell-to-cell communication.

  J Ratajczak;M Wysoczynski;F Hayek;A Janowska-Wieczorek

  1634
  Citations

• Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

  W.-J. Song;M. G. Sullivan;R. D. Legare;S. Hutchings

  1255
  Citations

• A population of very small embryonic-like (VSEL) CXCR4 + SSEA-1 + Oct-4 + stem cells identified in adult bone marrow

  M Kucia;R Reca;F R Campbell;E Zuba-Surma

  1028
  Citations

• Trafficking of Normal Stem Cells and Metastasis of Cancer Stem Cells Involve Similar Mechanisms: Pivotal Role of the SDF-1–CXCR4 Axis

  Magda Kucia;Ryan Reca;Katarzyna Miekus;Jens Wanzeck

  1026
  Citations

• CXCR4-SDF-1 signalling, locomotion, chemotaxis and adhesion.

  Magda Kucia;Kacper Jankowski;Ryan Reca;Marcin Wysoczynski

  938
  Citations

• Migration of bone marrow and cord blood mesenchymal stem cells in vitro is regulated by stromal-derived factor-1-CXCR4 and hepatocyte growth factor-c-met axes and involves matrix metalloproteinases.

  Bo‐Ra Son;Leah A. Marquez‐Curtis;Magda Kucia;Marcin Wysoczynski

  920
  Citations

• Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer.

  Anna Janowska-Wieczorek;Marcin Wysoczynski;Marcin Wysoczynski;Jacek Kijowski;Jacek Kijowski;Leah Marquez-Curtis;Leah Marquez-Curtis

  887
  Citations

• Numerous growth factors, cytokines, and chemokines are secreted by human CD34(+) cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner.

  Marcin Majka;Marcin Majka;Anna Janowska-Wieczorek;Anna Janowska-Wieczorek;Janina Ratajczak;Janina Ratajczak;Karen Ehrenman;Karen Ehrenman

  753
  Citations

• The pleiotropic effects of the SDF-1-CXCR4 axis in organogenesis, regeneration and tumorigenesis.

  Mariusz Z Ratajczak;Ewa Zuba-Surma;Magda Kucia;Ryan Reca

  586
  Citations

• Cells Expressing Early Cardiac Markers Reside in the Bone Marrow and Are Mobilized Into the Peripheral Blood After Myocardial Infarction

  Magda Kucia;Buddhadeb Dawn;Greg Hunt;Yiru Guo

  465
  Citations

• Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells ‘hide out’ in the bone marrow

  M Z Ratajczak;M Kucia;M Kucia;R Reca;M Majka

  461
  Citations

• Platelet-derived microparticles bind to hematopoietic stem/progenitor cells and enhance their engraftment

  Anna Janowska-Wieczorek;Marcin Majka;Jacek Kijowski;Monika Baj-Krzyworzeka

  447
  Citations

• Platelet-derived microparticles stimulate proliferation, survival, adhesion, and chemotaxis of hematopoietic cells.

  Monika Baj-Krzyworzeka;Marcin Majka;Domenico Pratico;Janina Ratajczak

  432
  Citations

• Pivotal role of paracrine effects in stem cell therapies in regenerative medicine: can we translate stem cell-secreted paracrine factors and microvesicles into better therapeutic strategies?

  M Z Ratajczak;M Kucia;T Jadczyk;N J Greco

  414
  Citations

• Platelet- and megakaryocyte-derived microparticles transfer CXCR4 receptor to CXCR4-null cells and make them susceptible to infection by X4-HIV.

  Tomasz Rozmyslowicz;Marcin Majka;Jacek Kijowski;Samuel L Murphy

  386
  Citations

• Tissue-specific muscle, neural and liver stem/progenitor cells reside in the bone marrow, respond to an SDF-1 gradient and are mobilized into peripheral blood during stress and tissue injury

  Magda Kucia;Janina Ratajczak;Janina Ratajczak;Ryan Reca;Ryan Reca;Anna Janowska-Wieczorek;Anna Janowska-Wieczorek

  352
  Citations

• Novel insight into stem cell mobilization-Plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex

  Mariusz Z. Ratajczak;HakMo Lee;Marcin Wysoczynski;Wu Wan

  352
  Citations

• Incorporation of CXCR4 into membrane lipid rafts primes homing-related responses of hematopoietic stem/progenitor cells to an SDF-1 gradient.

  Marcin Wysoczynski;Ryan Reca;Janina Ratajczak;Magda Kucia

  321
  Citations

• A hypothesis for an embryonic origin of pluripotent Oct-4+ stem cells in adult bone marrow and other tissues

  M Z Ratajczak;B Machalinski;W Wojakowski;J Ratajczak

  321
  Citations