What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Internal medicine
The scientist’s investigation covers issues in Thrombin, Biochemistry, Antithrombin, Internal medicine and Molecular biology.
His Thrombin research incorporates elements of Surgery, Cell biology, Cardiopulmonary bypass and Fibrin.
His Biochemistry research is multidisciplinary, incorporating elements of Inflammation and Epitope.
His research in Antithrombin intersects with topics in Anticoagulant, Serpin, Activated protein C resistance and Coagulation.
The Internal medicine study combines topics in areas such as Endocrinology and Cardiology.
The various areas that David A. Lane examines in his Molecular biology study include Plasma protein binding, Von Willebrand factor type A domain, Proteolysis, Exon and Epitope mapping.
His most cited work include:
- Using Antibodies: A Laboratory Manual (2641 citations)
- Inherited thrombophilia: Part 1. (517 citations)
- Role of hemostatic gene polymorphisms in venous and arterial thrombotic disease. (459 citations)
What are the main themes of his work throughout his whole career to date?
David A. Lane spends much of his time researching Biochemistry, Thrombin, Molecular biology, Antithrombin and Internal medicine.
His Thrombin research includes elements of Fibrinogen, Coagulation and Fibrin.
His work carried out in the field of Molecular biology brings together such families of science as Proteolysis, Protein C and Antigen.
In his research, Protein S is intimately related to Genetics, which falls under the overarching field of Antithrombin.
His Internal medicine study integrates concerns from other disciplines, such as Gastroenterology, Endocrinology and Cardiology.
David A. Lane has researched Heparin in several fields, including Anticoagulant and Pharmacology.
He most often published in these fields:
- Biochemistry (28.19%)
- Thrombin (20.72%)
- Molecular biology (21.45%)
What were the highlights of his more recent work (between 2007-2020)?
- ADAMTS13 (6.51%)
- Von Willebrand factor (5.30%)
- Biochemistry (28.19%)
In recent papers he was focusing on the following fields of study:
David A. Lane mainly focuses on ADAMTS13, Von Willebrand factor, Biochemistry, Binding site and Von Willebrand factor type A domain.
His research integrates issues of Plasma protein binding, Ligand binding assay, Calcium and Proteolysis in his study of Binding site.
His Von Willebrand factor type A domain study combines topics from a wide range of disciplines, such as Vicinal and Molecular biology, Cleavage.
His Mutant research extends to Molecular biology, which is thematically connected.
His study in Protein S is interdisciplinary in nature, drawing from both Thrombin, Prothrombinase and Tissue factor pathway inhibitor, Kunitz domain.
His biological study spans a wide range of topics, including Serine protease and Coagulation.
Between 2007 and 2020, his most popular works were:
- Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor. (184 citations)
- An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF. (107 citations)
- High VWF low ADAMTS13 and oral contraceptives increase the risk of ischemic stroke and myocardial infarction in young women. (98 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Internal medicine
David A. Lane mainly investigates Biochemistry, Von Willebrand factor type A domain, ADAMTS13, Von Willebrand factor and Binding site.
His study in Protein S, Active site, Enzyme and Cysteine are all subfields of Biochemistry.
His studies deal with areas such as Plasma protein binding, Scissile bond, Molecular biology, Glycan and Protein structure as well as Von Willebrand factor type A domain.
His Molecular biology study frequently draws parallels with other fields, such as Mutant.
His ADAMTS13 research also works with subjects such as
- Protein folding and related Ligand binding assay,
- Epitope which connect with Polyclonal antibodies.
David A. Lane interconnects ADAM Proteins and Proteolysis in the investigation of issues within Binding site.
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