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2023

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Best Scientists

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Medicine

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171
Citations
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Research.com Recognitions

  • 2025 - Research.com Best Scientists Award
  • 2023 - Research.com Medicine in Netherlands Leader Award
  • 2008 - Royal Netherlands Academy of Arts and Sciences
  • 2002 - Spinoza Prize, Dutch Research Council

Overview

Frits R. Rosendaal is affiliated with Leiden University Medical Center in the Netherlands. Their academic focus lies primarily within the field of Medicine, with notable contributions in subfields such as Hematology, Cardiology and Cardiovascular Medicine, Genetics, Internal Medicine, and Surgery.

The researcher's work covers a range of topics, including:

  • Blood Coagulation and Thrombosis Mechanisms
  • Venous Thromboembolism Diagnosis and Management
  • Hemophilia Treatment and Research
  • Genetic Associations and Epidemiology
  • Platelet Disorders and Treatments
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies

Frits R. Rosendaal has authored multiple research papers, including the following notable recent publications:

  • Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles, 2022, Nature Genetics
  • Interleukin-6 Signaling Effects on Ischemic Stroke and Other Cardiovascular Outcomes, 2020, Circulation Genomic and Precision Medicine
  • Review of: "Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial Gautret et al 2010, 2020, International Journal of Antimicrobial Agents
  • The prevalence of metabolic syndrome and its association with body fat distribution in middle-aged individuals from Indonesia and the Netherlands: a cross-sectional analysis of two population-based studies, 2020, Diabetology & Metabolic Syndrome
  • Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19, 2021, Nature Immunology

The researcher frequently collaborates with several other scientists, including:

  • Astrid van Hylckama Vlieg
  • Renée de Mutsert
  • Ko Willems van Dijk
  • Raymond Noordam
  • Ruifang Li-Gao

Frits R. Rosendaal's work is often published in a set of key venues, such as:

  • Research and Practice in Thrombosis and Haemostasis
  • Journal of Thrombosis and Haemostasis
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Annals of the Rheumatic Diseases
  • Blood

This researcher has been recognized with awards including the Spinoza Prize from the Dutch Research Council in 2002 and membership in the Royal Netherlands Academy of Arts and Sciences since 2008.

Best Publications

  • Mutation in blood coagulation factor V associated with resistance to activated protein C

    Rogier M. Bertina;Bobby P. C. Koeleman;Ted Koster;Frits R. Rosendaal

  • A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis.

    Swibertus R. Poort;Frits R. Rosendaal;Pieter H. Reitsma;Rogier M. Bertina

  • The Scylla and Charybdis of oral anticoagulant treatment

    F.R. Rosendaal

  • Malignancies, Prothrombotic Mutations, and the Risk of Venous Thrombosis

    Jeanet W. Blom;Catharina Jacoba Maria Doggen;Susanne Osanto;Frits R. Rosendaal

  • Venous thrombosis: a multicausal disease.

    FR Rosendaal

  • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

    Heribert Schunkert;Inke R. König;Sekar Kathiresan;Muredach P. Reilly

  • Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study

    T Koster;JP Vandenbroucke;FR Rosendaal;H de Ronde

  • Incidence and mortality of venous thrombosis: a population‐based study

    I. A. Næss;S. C. Christiansen;P. Romundstad;S. C. Cannegieter

  • Increased Risk of Venous Thrombosis in Oral-Contraceptive Users Who Are Carriers of Factor V Leiden Mutation

    Jan P. Vandenbroucke;Ted Koster;Ernest Briet;Pieter H. Reitsma

  • Lowering blood homocysteine with folic acid based supplements: Meta-analysis of randomised trials

    L.E. Brattstrom;M. den Heijer;H.J. Blom;G. Bos

  • Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep-vein thrombosis

    T. Koster;J.P. Vandenbroucke;F.R. Rosendaal;E. Briët

  • Hyperhomocysteinemia as a risk factor for deep-vein thrombosis

    M. Den Heijer;T. Koster;H. J. Blom;G. M. J. Bos

  • High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance)

    FR Rosendaal;T Koster;JP Vandenbroucke;PH Reitsma

  • The Risk of Myocardial Infarction Associated With Antihypertensive Drug Therapies

    Bruce M. Psaty;Susan R. Heckbert;Thomas D. Koepsell;David S. Siscovick

  • Thromboembolic and bleeding complications in patients with mechanical heart valve prostheses.

    S C Cannegieter;F R Rosendaal;E Briët

  • Preoperative anaemia and postoperative outcomes in non-cardiac surgery: a retrospective cohort study

    Khaled M Musallam;Khaled M Musallam;Hani M Tamim;Hani M Tamim;Toby Richards;Donat R Spahn

  • Optimal oral anticoagulant therapy in patients with mechanical heart valves.

    S.C. Cannegieter;F.R. Rosendaal;A.R. Wintzen;F.J.M. van der Meer

  • Definitions in hemophilia. Recommendation of the scientific subcommittee on factor VIII and factor IX of the scientific and standardization committee of the International Society on Thrombosis and Haemostasis.

    Gilbert C. Ii White;Frits Rosendaal;Louis M. Aledort;Jeanne M. Lusher

  • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

    Mary F. Feitosa;Aldi T. Kraja;Daniel I. Chasman;Yun J. Sung

  • Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

    Aysu Okbay;Bart M L Baselmans;Jan-Emmanuel De Neve;Patrick Turley

Frequent Co-Authors

Bruce M. Psaty
Bruce M. Psaty University of Washington
Dennis O. Mook-Kanamori
Dennis O. Mook-Kanamori Leiden University Medical Center
Jan P. Vandenbroucke
Jan P. Vandenbroucke Leiden University Medical Center
Flora Peyvandi
Flora Peyvandi University of Milan
Susan R. Heckbert
Susan R. Heckbert University of Washington
J. Wouter Jukema
J. Wouter Jukema Leiden University Medical Center
Margreet Kloppenburg
Margreet Kloppenburg Leiden University Medical Center
Ko Willems van Dijk
Ko Willems van Dijk Leiden University Medical Center
Hildo J. Lamb
Hildo J. Lamb Leiden University Medical Center
Nicholas L. Smith
Nicholas L. Smith University of Washington

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