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David-Alexandre Trégouët

David-Alexandre Trégouët

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Genetics
France
2024

D-Index & Metrics

Genetics

D-Index
87
Citations
37830
World Ranking
1196
National Ranking
42

Medicine

D-Index
88
Citations
38873
World Ranking
12956
National Ranking
404

Research.com Recognitions

  • 2024 - Research.com Genetics in France Leader Award

Overview

David-Alexandre Trégouët is affiliated with the University of Bordeaux in France. Their research primarily focuses on Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions across related subfields.

The scientist's main fields of study encompass Medicine with 214 publications and Biochemistry, Genetics and Molecular Biology totaling 122 publications. Within these broad areas, they have worked extensively in several subfields including Hematology (66 publications), Molecular Biology (61 publications), Genetics (55 publications), Cardiology and Cardiovascular Medicine (32 publications), and Internal Medicine (26 publications).

Research topics covered in their work span Blood Coagulation and Thrombosis Mechanisms, Genetic Associations and Epidemiology, Venous Thromboembolism Diagnosis and Management, Platelet Disorders and Treatments, RNA modifications and cancer, Cancer-related gene regulation, and Myeloproliferative Neoplasms: Diagnosis and Treatment.

Their recent papers illustrate a focus on cardiovascular and cerebral conditions with notable studies such as:

  • Genome-wide analysis identifies novel susceptibility loci for myocardial infarction, 2020, European Heart Journal
  • Cerebral small vessel disease genomics and its implications across the lifespan, 2020, Nature Communications
  • Interleukin-6 Signaling Effects on Ischemic Stroke and Other Cardiovascular Outcomes, 2020, Circulation Genomic and Precision Medicine
  • Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease, 2023, Nature Medicine
  • Genome-wide association analysis in dilated cardiomyopathy reveals two new players in systolic heart failure on chromosomes 3p25.1 and 22q11.23, 2021, European Heart Journal

The scientist often collaborates with other researchers, with frequent coauthors including Pierre-Emmanuel Morange, Jean-François Deleuze, Pierre Suchon, Anne Boland, and Gaëlle Munsch.

Publication venues where their work appears regularly include bioRxiv (Cold Spring Harbor Laboratory) with 28 publications, Journal of Thrombosis and Haemostasis with 13, Blood with 7, Circulation with 6, and Nature Communications with 5 publications.

Best Publications

  • Genomewide association analysis of coronary artery disease.

    Nilesh J. Samani;Jeanette Erdmann;Alistair S. Hall;Christian Hengstenberg

  • Large-scale association analysis identifies new risk loci for coronary artery disease

    Panos Deloukas;Stavroula Kanoni;Christina Willenborg;Martin Farrall

  • Genetic studies of body mass index yield new insights for obesity biology

    Adam E. Locke;Bratati Kahali;Sonja I. Berndt;Anne E. Justice

  • DNA methylation and body-mass index: a genome-wide analysis

    Katherine J Dick;Katherine J Dick;Christopher P Nelson;Christopher P Nelson;Loukia Tsaprouni;Johanna K Sandling;Johanna K Sandling

  • Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

    Sonja I Berndt;Stefan Gustafsson;Stefan Gustafsson;Reedik Mägi;Reedik Mägi;Andrea Ganna

  • Genetics and Beyond – The Transcriptome of Human Monocytes and Disease Susceptibility

    Tanja Zeller;Philipp Wild;Silke Szymczak;Maxime Rotival

  • New susceptibility locus for coronary artery disease on chromosome 3q22.3

    Jeanette Erdmann;Anika Großhennig;Peter S Braund;Inke R König

  • A novel channelopathy in pulmonary arterial hypertension.

    Lijiang Ma;Danilo Roman-Campos;Eric D. Austin;Mélanie Eyries

  • Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease

    David-Alexandre Trégouët;Inke R König;Jeanette Erdmann;Alexandru Munteanu

  • Cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genotypes as determinants of acenocoumarol sensitivity

    Laurent Bodin;Céline Verstuyft;David-Alexandre Tregouet;Annie Robert

  • Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

    Nathan O. Stitziel;Kathleen E. Stirrups;Nicholas G. D. Masca;Jeanette Erdmann

  • Repeated Replication and a Prospective Meta-Analysis of the Association Between Chromosome 9p21.3 and Coronary Artery Disease

    Heribert Schunkert;Anika Götz;Peter Braund;Ralph McGinnis

  • A new algorithm for haplotype‐based association analysis: the Stochastic‐EM algorithm

    D. A. Tregouet;S. Escolano;L. Tiret;A. Mallet

  • EIF2AK4 mutations cause pulmonary veno-occlusive disease, a recessive form of pulmonary hypertension

    Mélanie Eyries;David Montani;Barbara Girerd;Claire Perret

  • Human herpesvirus 8 transmission from mother to child and between siblings in an endemic population

    Sabine Plancoulaine;Sabine Plancoulaine;Laurent Abel;Laurent Abel;Monique van Beveren;David-Alexandre Trégouët

  • A new JAVA interface implementation of THESIAS

    D. A. Tregouet;V. Garelle

  • Common susceptibility alleles are unlikely to contribute as strongly as the FV and ABO loci to VTE risk: results from a GWAS approach

    David-Alexandre Trégouët;Simon Heath;Noémie Saut;Christine Biron-Andreani

  • Clinical outcomes of pulmonary arterial hypertension in patients carrying an ACVRL1 (ALK1) mutation.

    Barbara Girerd;David Montani;Florence Coulet;Benjamin Sztrymf

  • Thymidylate synthase gene polymorphism predicts toxicity in colorectal cancer patients receiving 5-fluorouracil-based chemotherapy

    Thierry Lecomte;Jean-Marc Ferraz;Franck Zinzindohoué;Marie-Anne Loriot

  • Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

    Sonja I. Berndt;Stefan Gustafsson;Reedik Maegi;Andrea Ganna

Frequent Co-Authors

Pierre-Emmanuel Morange
Pierre-Emmanuel Morange Aix-Marseille University
Laurence Tiret
Laurence Tiret Sorbonne University
François Cambien
François Cambien University of Bordeaux
Nilesh J. Samani
Nilesh J. Samani University of Leicester
Marie-Christine Alessi
Marie-Christine Alessi Aix-Marseille University
Daniel I. Chasman
Daniel I. Chasman Brigham and Women's Hospital
Nicholas L. Smith
Nicholas L. Smith University of Washington
Jeanette Erdmann
Jeanette Erdmann University of Lübeck
Michel Marre
Michel Marre Université Paris Cité

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