World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
92
Citations
33849
World Ranking
2199
National Ranking
1187

Research.com Recognitions

  • 2008 - AAI-BD Biosciences Investigator Award, American Association of Immunologists
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Pamela L. Schwartzberg is affiliated with the National Institutes of Health in the United States. Their research primarily centers on immunology and microbiology with additional contributions in medicine. The scientist's work covers subfields including immunology, oncology, molecular biology, infectious diseases, and hematology.

The research topics addressed by Pamela L. Schwartzberg include:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • CAR-T cell therapy research
  • Immunotherapy and Immune Responses
  • SARS-CoV-2 and COVID-19 Research
  • Inflammasome and immune disorders
  • Cell Adhesion Molecules Research

Schwartzberg has published extensively in a number of scientific journals. Frequent publication venues include:

  • Nature Immunology
  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Journal of Visualized Experiments

Several of their notable recent research papers are:

  • Broad immune activation underlies shared set point signatures for vaccine responsiveness in healthy individuals and disease activity in patients with lupus, 2020, Nature Medicine
  • BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells, 2021, Nature Immunology
  • Lessons learned: new insights on the role of cytokines in COVID-19, 2021, Nature Immunology
  • Common genetic susceptibility loci link PFAPA syndrome, Behçet's disease, and recurrent aphthous stomatitis, 2020, Proceedings of the National Academy of Sciences
  • Protein kinases: drug targets for immunological disorders, 2023, Nature Reviews Immunology

Frequently collaborating co-authors include:

  • Kalpana Manthiram
  • Dominic P. Golec
  • Qin Xu
  • Silvia Preite
  • Zenia Kaul

Recognition received by Schwartzberg includes the AAI-BD Biosciences Investigator Award from the American Association of Immunologists in 2008 and membership in the Association of American Physicians.

Best Publications

  • Defining ‘T cell exhaustion’

    Christian U Blank;W Nicholas Haining;Werner Held;Patrick G Hogan;Patrick G Hogan

  • PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes.

    Zuoming Sun;Christopher W. Arendt;Wilfried Ellmeier;Wilfried Ellmeier;Edward M. Schaeffer;Edward M. Schaeffer

  • A Critical Role for IL-21 in Regulating Immunoglobulin Production

    Katsutoshi Ozaki;Rosanne Spolski;Carl G. Feng;Chen-Feng Qi

  • Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability.

    Brian P Eliceiri;Robert Paul;Pamela L Schwartzberg;John D Hood

  • A Mosaic Activating Mutation in AKT1 Associated with the Proteus Syndrome

    Marjorie J Lindhurst;Julie C Sapp;Jamie K. Teer;Jennifer J Johnston

  • SAP-controlled T-B cell interactions underlie germinal centre formation.

    Hai Qi;Jennifer L. Cannons;Frederick Klauschen;Pamela L. Schwartzberg

  • T Helper Cell Fate Specified by Kinase-Mediated Interaction of T-bet with GATA-3

    Eun Sook Hwang;Susanne J. Szabo;Pamela L. Schwartzberg;Laurie H. Glimcher

  • Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency

    Carrie L Lucas;Hye Sun Kuehn;Fang Zhao;Julie E Niemela

  • Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.

    Jing He;Louis M Tsai;Yew A Leong;Xin Jack Hu;Xin Jack Hu

  • Follicular helper T cells are required for systemic autoimmunity.

    Michelle A. Linterman;Robert J. Rigby;Raphael. K. Wong;Di Yu

  • The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness.

    Tuoqi Wu;Yun Ji;E. Ashley Moseman;Haifeng C. Xu

  • T-Cell Signaling Regulated by the Tec Family Kinase, Itk

    Amy H. Andreotti;Pamela L. Schwartzberg;Raji E. Joseph;Leslie J. Berg

  • SLAM Family Receptors and SAP Adaptors in Immunity

    Jennifer L. Cannons;Stuart G. Tangye;Pamela L. Schwartzberg

  • Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection.

    Chen Yao;Hong-Wei Sun;Neal E. Lacey;Yun Ji

  • Optimal Germinal Center Responses Require a Multistage T Cell:B Cell Adhesion Process Involving Integrins, SLAM-Associated Protein, and CD84

    Jennifer L. Cannons;Hai Qi;Kristina T. Lu;Mala Dutta;Mala Dutta

  • SAP is required for generating long-term humoral immunity

    Shane Crotty;Ellen N. Kersh;Jennifer Cannons;Pamela L. Schwartzberg

  • Early Th1 Cell Differentiation Is Marked by a Tfh Cell-like Transition

    Shingo Nakayamada;Yuka Kanno;Hayato Takahashi;Dragana Jankovic

  • Requirement for Tec Kinases Rlk and Itk in T Cell Receptor Signaling and Immunity

    Edward M. Schaeffer;Jayanta Debnath;George Yap;Daniel McVicar

  • Regulation of NKT cell development by SAP, the protein defective in XLP.

    Kim E. Nichols;Jamie Hom;Shun You Gong;Arupa Ganguly

  • Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations

    Pamela L. Schwartzberg;Alan M. Stall;Jeff D. Hardin;Katherine S. Bowdish

Frequent Co-Authors

Stacie M. Anderson
Stacie M. Anderson National Institutes of Health
Stephen P. Goff
Stephen P. Goff Columbia University Medical Center
Martha Kirby
Martha Kirby National Institutes of Health
Stuart G. Tangye
Stuart G. Tangye Garvan Institute of Medical Research
David A. Cheresh
David A. Cheresh University of California, San Diego
Alan Sher
Alan Sher National Institute of Allergy and Infectious Diseases
Dorian B. McGavern
Dorian B. McGavern National Institutes of Health
John J. O'Shea
John J. O'Shea National Institutes of Health
Michael J. Lenardo
Michael J. Lenardo National Institute of Allergy and Infectious Diseases
Cindy S. Ma
Cindy S. Ma Garvan Institute of Medical Research

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