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Microbiology
USA
2026

D-Index & Metrics

Microbiology

D-Index
124
Citations
74562
World Ranking
111
National Ranking
56

Medicine

D-Index
125
Citations
74742
World Ranking
3037
National Ranking
1675

Research.com Recognitions

  • 2026 - Research.com Microbiology in United States Leader Award
  • 2025 - Research.com Microbiology in United States Leader Award
  • 2020 - AAI-Steinman Award for Human Immunology Research, American Association of Immunologists
  • 2019 - Member of the National Academy of Sciences
  • 2019 - Member of the National Academy of Medicine (NAM)
  • 2015 - Fellow of the American Academy of Arts and Sciences
  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the Association of American Physicians
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the Association of American Physicians
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the Association of American Physicians
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the Association of American Physicians
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the Association of American Physicians
  • Fellow of The Academy of Medical Sciences, United Kingdom

Overview

Michael J. Lenardo is affiliated with the National Institute of Allergy and Infectious Diseases in the United States. Their research primarily spans the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Key subfields in which they have contributed include Immunology, Genetics, Molecular Biology, Surgery, and Oncology.

The main topics of Michael J. Lenardo's work focus on Immunodeficiency and Autoimmune Disorders, Immune Cell Function and Interaction, the Complement system in diseases, Multiple Sclerosis Research Studies, CAR-T cell therapy research, Cancer Immunotherapy and Biomarkers, and T-cell and B-cell Immunology.

Their notable recent publications include:

  • A guide to cancer immunotherapy: from T cell basic science to clinical practice (2020) in Nature Reviews Immunology
  • Mucus sialylation determines intestinal host-commensal homeostasis (2022) in Cell
  • A randomized, placebo-controlled phase 3 trial of the PI3Kδ inhibitor leniolisib for activated PI3Kδ syndrome (2022) in Blood
  • HEM1 deficiency disrupts mTORC2 and F-actin control in inherited immunodysregulatory disease (2020) in Science
  • Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency (2020) in Blood

Frequent co-authors of Michael J. Lenardo include Ahmet Özen, Safa Barış, Elif Karakoç-Aydiner, Yikun Yao, and Ann Y. Park.

Publications are often found in the following venues:

  • The Journal of Immunology
  • Nature Immunology
  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Blood

Michael J. Lenardo's professional recognitions include the AAI-Steinman Award for Human Immunology Research from the American Association of Immunologists in 2020, membership in the National Academy of Medicine and the National Academy of Sciences since 2019, and fellowship in the American Academy of Arts and Sciences, the American Association for the Advancement of Science (AAAS), The Academy of Medical Sciences (United Kingdom), and membership in the Association of American Physicians.

Best Publications

  • The TNF and TNF receptor superfamilies: integrating mammalian biology.

    Richard M. Locksley;Nigel Killeen;Michael J. Lenardo

  • A guide to cancer immunotherapy: from T cell basic science to clinical practice.

    Alex D. Waldman;Jill M. Fritz;Michael J. Lenardo

  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  • NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control

    Michael J. Lenardo;David Baltimore

  • Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

    Galen H Fisher;Fredric J Rosenberg;Stephen E Straus;Janet K Dale

  • 30 Years of NF-κB: A Blossoming of Relevance to Human Pathobiology

    Qian Zhang;Michael J. Lenardo;David Baltimore

  • Termination of autophagy and reformation of lysosomes regulated by mTOR

    Li Yu;Christina K. McPhee;Christina K. McPhee;Lixin Zheng;Gonzalo A. Mardones;Gonzalo A. Mardones

  • CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation–mediated apoptosis of effector CD4+ T cells

    Pushpa Pandiyan;Lixin Zheng;Satoru Ishihara;Jennifer Reed

  • Regulation of an ATG7-beclin 1 Program of Autophagic Cell Death by Caspase-8

    Li Yu;Ajjai Alva;Helen Su;Parmesh Dutt

  • Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis.

    Michael J. Lenardo

  • NF-kappa B and Rel: participants in a multiform transcriptional regulatory system.

    Mariagrazia Grilli;Jason J.-S. Chiu;Michael J. Lenardo

  • Induction of apoptosis in mature T cells by tumour necrosis factor.

    Lixin Zheng;Galen Fisher;Robert E. Miller;Jacques Peschon

  • A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling.

    Francis Ka-Ming Chan;Hyung J. Chun;Lixin Zheng;Richard M. Siegel

  • Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environment.

    M Lenardo;K M Chan;F Hornung;H McFarland

  • Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

    Hye Sun Kuehn;Weiming Ouyang;Bernice Lo;Elissa K. Deenick;Elissa K. Deenick

  • Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

    Hyung J. Chun;Lixin Zheng;Manzoor Ahmad;Jin Wang;Jin Wang

  • Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations

    Richard M. Siegel;John K. Frederiksen;David A. Zacharias;Francis Ka Ming Chan

  • Autophagic programmed cell death by selective catalase degradation

    Li Yu;Fengyi Wan;Sudeshna Dutta;Sarah Welsh

  • Inherited Human Caspase 10 Mutations Underlie Defective Lymphocyte and Dendritic Cell Apoptosis in Autoimmune Lymphoproliferative Syndrome Type II

    Jin Wang;Lixin Zheng;Adrian Lobito;Francis Ka Ming Chan

  • Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy

    Bernice Lo;Kejian Zhang;Wei Lu;Lixin Zheng

  • Protein-binding sites in Ig gene enhancers determine transcriptional activity and inducibility

    Michael Lenardo;Jacqueline W. Pierce;David Baltimore

Frequent Co-Authors

Lixin Zheng
Lixin Zheng National Institutes of Health
Helen C. Su
Helen C. Su National Institutes of Health
Richard M. Siegel
Richard M. Siegel National Institutes of Health
Jennifer M. Puck
Jennifer M. Puck University of California, San Francisco
Sharon E. Straus
Sharon E. Straus University of Toronto
Jin Wang
Jin Wang Houston Methodist
Thomas A. Fleisher
Thomas A. Fleisher National Institutes of Health
Francis Ka-Ming Chan
Francis Ka-Ming Chan Duke University
David Baltimore
David Baltimore California Institute of Technology
Juan Carlos Zúñiga-Pflücker
Juan Carlos Zúñiga-Pflücker University of Toronto

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