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2025
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Molecular Biology
USA
2025

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Best Scientists

D-Index
240
Citations
235622
World Ranking
67
National Ranking
47

Molecular Biology

D-Index
240
Citations
235059
World Ranking
6
National Ranking
3

Research.com Recognitions

  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United States Leader Award
  • 2023 - Research.com Molecular Biology in United States Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in United States Leader Award
  • 2019 - Distinguished Fellows of the American Association of Immunologists (AAI)
  • 2014 - Fellow, National Academy of Inventors
  • 2009 - AAI Excellence in Mentoring Award, American Association of Immunologists
  • 2002 - AMA Scientific Achievement Award, American Medical Association
  • 2000 - Warren Alpert Foundation Prize For their research that contributed to the development of a drug that effectively treats chronic megelogenous leukemia and other forms of cancer.
  • 1999 - US President's National Medal of Science "For his fundamental discoveries in virology, tumor biology and immunology, notably the discovery of how tumor-causing viruses multiply; for his devotion to building excellence in scientific institutions; and for his statesmanship in fostering communication between scientists and the general public.", Presented by President William Clinton in a White House (East Room) ceremony on Tuesday, March 14, 2000.
  • 1999 - Member of Academia Europaea
  • 1988 - Member of the National Academy of Medicine (NAM)
  • 1987 - Fellow of the Royal Society, United Kingdom
  • 1980 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1975 - Nobel Prize for their discoveries concerning the interaction between tumour viruses and the genetic material of the cell
  • 1974 - Fellow of the American Academy of Arts and Sciences
  • 1974 - Canada Gairdner International Award
  • 1974 - Member of the National Academy of Sciences

Overview

David Baltimore is affiliated with the California Institute of Technology in the United States. Their research spans multiple areas within biochemistry, genetics, and molecular biology, with a particular focus on molecular biology, immunology, oncology, genetics, and epidemiology.

Their recent publications cover a range of topics and are published in several well-known scientific journals:

  • Non-viral precision T cell receptor replacement for personalized cell therapy, 2022, Nature
  • Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line, 2020, Nature Communications
  • Safety and tolerability of AAV8 delivery of a broadly neutralizing antibody in adults living with HIV: a phase 1, dose-escalation trial, 2022, Nature Medicine
  • Sequence-dependent dynamics of synthetic and endogenous RSSs in V(D)J recombination, 2020, Nucleic Acids Research
  • NF-κB: master regulator of cellular responses in health and disease, 2025, Immunity & Inflammation

Key areas of research addressed in their work include:

  • CAR-T cell therapy research
  • CRISPR and Genetic Engineering
  • Virus-based gene therapy research
  • T-cell and B-cell Immunology
  • Immune Response and Inflammation
  • Bacteriophages and microbial interactions
  • Single-cell and spatial transcriptomics

Their frequent co-authors include Antoni Ribas, James R. Heath, Yue Lü, Bartosz Chmielowski, and Yapeng Su.

The scientist regularly publishes in the following venues:

  • Nature Communications
  • Nature
  • Nature Medicine
  • Nucleic Acids Research
  • Immunity & Inflammation

Among the honors received by David Baltimore are the Nobel Prize awarded in 1975 for discoveries concerning the interaction between tumour viruses and the genetic material of the cell, the US President's National Medal of Science in 1999, and the Warren Alpert Foundation Prize in 2000 for research contributing to cancer drug development.

Other distinctions include membership in the National Academy of Sciences, the American Academy of Arts and Sciences, the American Association for the Advancement of Science, the National Academy of Medicine, and Academia Europaea. Additional awards include the Distinguished Fellows of the American Association of Immunologists in 2019, Fellow of the National Academy of Inventors, and the AMA Scientific Achievement Award.

Best Publications

  • An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death

    Amer A. Beg;David Baltimore

  • NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

    Konstantin D. Taganov;Mark P. Boldin;Kuang-Jung Chang;David Baltimore

  • NF-κB: Ten Years After

    Patrick A Baeuerle;David Baltimore

  • Multiple nuclear factors interact with the immunoglobulin enhancer sequences.

    Ranjan Sen;David Baltimore

  • A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

    Cornelis Murre;Patrick Schonleber McCaw;David Baltimore

  • Production of high titer helper-free retroviruses by transient transfection

    Warren S. Pear;Garry P. Nolan;Martin L. Scott;David Baltimore

  • An inducible transcription factor activates expression of human immunodeficiency virus in T cells

    Gary Nabel;David Baltimore

  • Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism

    Ranjan Sen;David Baltimore

  • I kappa B: a specific inhibitor of the NF-kappa B transcription factor.

    Patrick A. Baeuerle;David Baltimore

  • Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

    GQ Daley;RA Van Etten;D Baltimore

  • Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of RNA Tumour Viruses

    David Baltimore

  • Germline Transmission and Tissue-Specific Expression of Transgenes Delivered by Lentiviral Vectors

    Carlos Lois;Elizabeth J. Hong;Shirley Pease;Eric J. Brown

  • Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B.

    Amer A. Beg;William C. Sha;Roderick T. Bronson;Sankar Ghosh

  • The IκB-NF-κB Signaling Module: Temporal Control and Selective Gene Activation

    Alexander Hoffmann;Andre Levchenko;Martin L. Scott;David Baltimore

  • MicroRNA-155 is induced during the macrophage inflammatory response

    Ryan M. O'Connell;Konstantin D. Taganov;Mark P. Boldin;Genhong Cheng

  • NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control

    Michael J. Lenardo;David Baltimore

  • Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

    Richard Mann;Richard C. Mulligan;David Baltimore

  • Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence.

    Cornelis Murre;Patrick Schonleber McCaw;H. Vaessin;M. Caudy

  • The “initiator” as a transcription control element

    Stephen T. Smale;David Baltimore

  • RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination.

    Marjorie A. Oettinger;David G. Schatz;Carolyn Gorka;David Baltimore

Frequent Co-Authors

Paul Matsudaira
Paul Matsudaira National University of Singapore
Dinesh S. Rao
Dinesh S. Rao University of Florida
Antoni Ribas
Antoni Ribas University of California, Los Angeles
Ryan M. O'Connell
Ryan M. O'Connell University of Utah
James R. Heath
James R. Heath California Institute of Technology
Frederick W. Alt
Frederick W. Alt Boston Children's Hospital
Owen N. Witte
Owen N. Witte University of California, Los Angeles
Martin L. Scott
Martin L. Scott Biogen (United States)
David G. Schatz
David G. Schatz Yale University

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