World's Best Scientists 2026 revealed!
David G. Schatz

David G. Schatz

D-Index & Metrics

Immunology

D-Index
78
Citations
26348
World Ranking
1732
National Ranking
851

Molecular Biology

D-Index
82
Citations
27310
World Ranking
933
National Ranking
498

Research.com Recognitions

  • 2018 - Member of the National Academy of Sciences
  • 2014 - Fellow of the American Academy of Arts and Sciences

Overview

David G. Schatz is affiliated with Yale University in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with substantial contributions to immunology and microbiology as well as medicine. The scientist's work spans various subfields including molecular biology, immunology, plant science, genetics, and oncology.

The main topics covered by their research include:

  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • RNA and protein synthesis mechanisms
  • Genomics and Chromatin Dynamics
  • Chromosomal and Genetic Variations
  • CRISPR and Genetic Engineering
  • Viral Infections and Immunology Research

Notable recent papers authored by David G. Schatz include:

  • Structural basis of mismatch recognition by a SARS-CoV-2 proofreading enzyme, 2021, Science
  • Structural insights into the evolution of the RAG recombinase, 2021, Nature Reviews Immunology
  • Structural visualization of transcription activated by a multidrug-sensing MerR family regulator, 2021, Nature Communications
  • HMCES protects immunoglobulin genes specifically from deletions during somatic hypermutation, 2022, Genes & Development
  • Nucleolar localization of RAG1 modulates V(D)J recombination activity, 2020, Proceedings of the National Academy of Sciences

Frequent co-authors collaborating with the scientist include Lizhen Wu, Eliza C. Martin, Filip Šenigl, Jianxiong Xiao, and Anurupa Devi Yadavalli.

The scientist's work has been published frequently in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • The Journal of Experimental Medicine
  • Cell Research
  • Science

David G. Schatz has received recognition in the scientific community, being named a fellow of the American Academy of Arts and Sciences in 2014 and elected as a member of the National Academy of Sciences in 2018.

Best Publications

  • RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination.

    Marjorie A. Oettinger;David G. Schatz;Carolyn Gorka;David Baltimore

  • The V(D)J Recombination Activating Gene, RAG-1

    David G. Schatz;Marjorie A. Oettinger;David Baltimore

  • Identifying differences in mRNA expression by representational difference analysis of cDNA

    M. Hubank;D.G. Schatz

  • Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

    Alka Agrawal;Quinn M. Eastman;David G. Schatz

  • The RAG proteins and V(D)J recombination: complexes, ends, and transposition.

    Sebastian D. Fugmann;Alfred Ian Lee;Penny E. Shockett;Isabelle J. Villey

  • Recombination centres and the orchestration of V(D)J recombination.

    David G. Schatz;Yanhong Ji

  • Two levels of protection for the B cell genome during somatic hypermutation

    Man Liu;Jamie L. Duke;Daniel J. Richter;Daniel J. Richter;Carola G. Vinuesa

  • V(D)J RECOMBINATION: Molecular Biology and Regulation

    David G. Schatz;Marjorie A. Oettinger;Mark S. Schlissel

  • V(D)J recombination: mechanisms of initiation.

    David G. Schatz;Patrick C. Swanson

  • Down-regulation of RAG1 and RAG2 gene expression in preB cells after functional immunoglobulin heavy chain rearrangement.

    Ulf Grawunder;Thomas M.J. Leu;David G. Schatz;Annick Werner

  • A modified tetracycline-regulated system provides autoregulatory, inducible gene expression in cultured cells and transgenic mice.

    Penny Shockett;Michael Difilippantonio;Nathan Hellman;David G. Schatz

  • Targeting of somatic hypermutation.

    Valerie H Odegard;David G Schatz

  • Genomic landscape of cutaneous T cell lymphoma

    Jaehyuk Choi;Gerald Goh;Trent Walradt;Bok S Hong

  • Productive T-cell receptor beta-chain gene rearrangement: coincident regulation of cell cycle and clonality during development in vivo.

    E. S. Hoffman;L. Passoni;T. Crompton;T. M. J. Leu

  • Neoteny in Lymphocytes: Rag1 and Rag2 Expression in Germinal Center B Cells

    Shuhua Han;Biao Zheng;David G. Schatz;Eugenia Spanopoulou

  • RAG1 and RAG2 Form a Stable Postcleavage Synaptic Complex with DNA Containing Signal Ends in V(D)J Recombination

    Alka Agrawal;David G Schatz

  • A link between double-strand break-related repair and V(D)J recombination: the scid mutation.

    Eric A. Hendrickson;Xiao-Qiang Qin;Edward A. Bump;David G. Schatz

  • The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system

    Jerold J.M. Chun;David G. Schatz;Marjorie A. Oettinger;Rudolf Jaenisch

  • Thymocyte expression of RAG-1 and RAG-2: termination by T cell receptor cross-linking.

    Laurence A. Turka;David G. Schatz;Marjorie A. Oettinger;Jerold J. M. Chun

  • Initiation of V(D)J recombination in vitro obeying the 12/23 rule

    Quinn M. Eastman;Thomas M. J. Leu;David G. Schatz

Frequent Co-Authors

David Baltimore
David Baltimore California Institute of Technology
Marjorie A. Oettinger
Marjorie A. Oettinger Harvard University
Frederick W. Alt
Frederick W. Alt Boston Children's Hospital
Rafael Casellas
Rafael Casellas The University of Texas MD Anderson Cancer Center
Craig H. Bassing
Craig H. Bassing Children's Hospital of Philadelphia
Pierre Pontarotti
Pierre Pontarotti Aix-Marseille University
Markus Müschen
Markus Müschen Yale University
Michael R. Lieber
Michael R. Lieber University of Southern California
Howard T. Petrie
Howard T. Petrie Scripps Research Institute
Richard A. Flavell
Richard A. Flavell Yale University

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