2018 - Member of the National Academy of Sciences
2014 - Fellow of the American Academy of Arts and Sciences
Molecular biology, Recombination-activating gene, Gene rearrangement, Gene and VJ recombination are his primary areas of study. David G. Schatz has included themes like Gene expression, Immunoglobulin heavy chain, T cell, T-cell receptor and Regulation of gene expression in his Molecular biology study. His Recombination-activating gene research is multidisciplinary, relying on both FLP-FRT recombination, RAG2 and Genome instability.
His biological study spans a wide range of topics, including Cleavage and Site-specific recombination. His work carried out in the field of Gene rearrangement brings together such families of science as Recombinase, Recombinase activity and Cellular differentiation. As a part of the same scientific family, David G. Schatz mostly works in the field of VJ recombination, focusing on DNA and, on occasion, Cell biology and Genetic recombination.
David G. Schatz spends much of his time researching Molecular biology, Genetics, Recombination-activating gene, Gene and VJ recombination. He combines subjects such as Gene rearrangement, T cell, T-cell receptor, Activation-induced deaminase and B cell with his study of Molecular biology. His studies in Recombination-activating gene integrate themes in fields like Transposable element, Transposase, RAG2, Cell biology and Severe combined immunodeficiency.
His RAG2 research is multidisciplinary, incorporating elements of Site-specific recombination and Active site. His studies examine the connections between Gene and genetics, as well as such issues in Somatic hypermutation, with regards to Cytidine deaminase, Germinal center, Mutation, Gene conversion and RNA polymerase II. His study in VJ recombination is interdisciplinary in nature, drawing from both Recombinase, FLP-FRT recombination, Recombination signal sequences and DNA.
David G. Schatz focuses on VJ recombination, Recombination-activating gene, Genetics, Gene and DNA. His VJ recombination research incorporates elements of Recombination signal sequences, Biophysics, Recombinase, Molecular biology and RAG2. His Molecular biology research is multidisciplinary, incorporating perspectives in T cell, DNA damage and Somatic cell.
His RAG2 study deals with Active site intersecting with Protein domain. His Recombination-activating gene study combines topics in areas such as Genome, Transposable element and Severe combined immunodeficiency. The various areas that he examines in his DNA study include Cleavage, RNA polymerase II holoenzyme, Recombination and DNA-binding protein.
His primary areas of investigation include VJ recombination, Genetics, Recombination-activating gene, Gene and Chromatin. His study in DNA, Recombination signal sequences and Recombinase falls within the category of Genetics. His work carried out in the field of DNA brings together such families of science as Recombination and DNA-binding protein.
His Recombination-activating gene study integrates concerns from other disciplines, such as Genome, Transposable element and RAG2. The concepts of his Gene study are interwoven with issues in Lesion, Immunology, Cytokine, DNA damage and Molecular biology. David G. Schatz incorporates Molecular biology and Cutaneous T-cell lymphoma in his research.
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RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination.
Marjorie A. Oettinger;David G. Schatz;Carolyn Gorka;David Baltimore.
Science (1990)
The V(D)J Recombination Activating Gene, RAG-1
David G. Schatz;Marjorie A. Oettinger;David Baltimore.
Cell (1989)
Identifying differences in mRNA expression by representational difference analysis of cDNA
M. Hubank;D.G. Schatz.
Nucleic Acids Research (1994)
Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system
Alka Agrawal;Quinn M. Eastman;David G. Schatz.
Nature (1998)
The RAG proteins and V(D)J recombination: complexes, ends, and transposition.
Sebastian D. Fugmann;Alfred Ian Lee;Penny E. Shockett;Isabelle J. Villey.
Annual Review of Immunology (2000)
V(D)J RECOMBINATION: Molecular Biology and Regulation
David G. Schatz;Marjorie A. Oettinger;Mark S. Schlissel.
Annual Review of Immunology (1992)
Two levels of protection for the B cell genome during somatic hypermutation
Man Liu;Jamie L. Duke;Daniel J. Richter;Daniel J. Richter;Carola G. Vinuesa.
Nature (2008)
Recombination centres and the orchestration of V(D)J recombination.
David G. Schatz;Yanhong Ji.
Nature Reviews Immunology (2011)
V(D)J recombination: mechanisms of initiation.
David G. Schatz;Patrick C. Swanson.
Annual Review of Genetics (2011)
A modified tetracycline-regulated system provides autoregulatory, inducible gene expression in cultured cells and transgenic mice.
Penny Shockett;Michael Difilippantonio;Nathan Hellman;David G. Schatz.
Proceedings of the National Academy of Sciences of the United States of America (1995)
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