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D-Index & Metrics

Molecular Biology

D-Index
63
Citations
15541
World Ranking
1801
National Ranking
901

Research.com Recognitions

  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Barry P. Sleckman is affiliated with the University of Alabama at Birmingham in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, along with Medicine. The subfields they have contributed to include Molecular Biology, Oncology, Public Health, Environmental and Occupational Health, Cancer Research, and General Health Professions.

Their work covers a range of topics with emphasis on DNA Repair Mechanisms, CRISPR and Genetic Engineering, PARP inhibition in cancer therapy, Epigenetics and DNA Methylation, Genomics and Chromatin Dynamics, DNA and Nucleic Acid Chemistry, and Cancer Immunotherapy and Biomarkers.

Selected recent papers authored or co-authored by Barry P. Sleckman include:

  • DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner, 2020, Nature Communications
  • Role of 53BP1 in end protection and DNA synthesis at DNA breaks, 2021, Genes & Development
  • RNF2 ablation reprograms the tumor-immune microenvironment and stimulates durable NK and CD4+ T-cell-dependent antitumor immunity, 2021, Nature Cancer
  • Does health literacy impact technological comfort in cancer patients?, 2021, The American Journal of Surgery
  • Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) activity is required for V(D)J recombination, 2021, The Journal of Experimental Medicine

Throughout their career, they have collaborated frequently with several researchers, including:

  • Bo-Ruei Chen
  • Jessica K. Tyler
  • André Nussenzweig
  • Nicholas Zolnerowich
  • Faith Fowler

Their publications have appeared in various venues, most notably in bioRxiv (Cold Spring Harbor Laboratory), eLife, Cancer Research, Nature Communications, and Genes & Development.

Barry P. Sleckman has been recognized with the distinction of Fellow of the American Association for the Advancement of Science (AAAS) in 2012. They are also a member of the Association of American Physicians.

Best Publications

  • A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

    Ken Cadwell;John Y. Liu;Sarah L. Brown;Hiroyuki Miyoshi

  • Distinct effects of T-bet in TH1 lineage commitment and IFN-γ production in CD4 and CD8 T cells

    Susanne J. Szabo;Brandon M. Sullivan;Claudia Stemmann;Abhay R. Satoskar

  • The Biologic Roles of CD2, CD4, and CD8 in T-Cell Activation

    B E Bierer;B P Sleckman;S E Ratnofsky;S J Burakoff

  • The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers.

    Dinis Pedro Calado;Yoshiteru Sasaki;Susana A Godinho;Alex Pellerin

  • ATM stabilizes DNA double-strand-break complexes during V(D)J recombination.

    Andrea L. Bredemeyer;Girdhar G. Sharma;Ching Yu Huang;Beth A. Helmink

  • ACCESSIBILITY CONTROL OF ANTIGEN-RECEPTOR VARIABLE-REGION GENE ASSEMBLY: Role of cis-Acting Elements

    Barry P. Sleckman;James R. Gorman;Frederick W. Alt

  • 53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions

    Elsa Callen;Michela Di Virgilio;Michael J. Kruhlak;Maria Nieto-Soler

  • Requirement for B Cell Linker Protein (BLNK) in B Cell Development

    Rajita Pappu;Alec M. Cheng;Bin Li;Qian Gong

  • 53BP1 facilitates long-range DNA end-joining during V(D)J recombination

    Simone Difilippantonio;Eric Gapud;Nancy Wong;Ching Yu Huang

  • Novel roles for A-type lamins in telomere biology and the DNA damage response pathway

    Ignacio Gonzalez-Suarez;Abena B Redwood;Stephanie M Perkins;Bart Vermolen

  • DNA Breaks and End Resection Measured Genome-wide by End Sequencing

    Andres Canela;Sriram Sridharan;Nicholas Sciascia;Anthony Tubbs

  • Formation of Dynamic γ-H2AX Domains along Broken DNA Strands is Distinctly Regulated by ATM and MDC1 and Dependent upon H2AX Densities in Chromatin

    Velibor Savic;Bu Yin;Nancy L. Maas;Andrea L. Bredemeyer

  • Expression and function of CD4 in a murine T-cell hybridoma.

    Barry P. Sleckman;Andrew Peterson;William K. Jones;Judith A. Foran

  • Function of the TCRα Enhancer in αβ and γδ T Cells

    Barry P Sleckman;Christiana G Bardon;Roger Ferrini;Laurie Davidson

  • Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule.

    Bassing Ch;Alt Fw;Hughes Mm;D'Auteuil M

  • Catalytic and Noncatalytic Roles of the CtIP Endonuclease in Double-Strand Break End Resection

    Nodar Makharashvili;Anthony T. Tubbs;Soo Hyun Yang;Hailong Wang

  • Inhibition of CD4+ T cell function by the HIV envelope protein, gp120.

    D C Diamond;B P Sleckman;T Gregory;L A Lasky

  • ATM Prevents the Persistence and Propagation of Chromosome Breaks in Lymphocytes

    Elsa Callén;Mila Jankovic;Simone Difilippantonio;Jeremy A. Daniel

  • The Response to and Repair of RAG-Mediated DNA Double-Strand Breaks

    Beth A. Helmink;Barry P. Sleckman

  • T-cell glucocorticoid receptor is required to suppress COX-2-mediated lethal immune activation.

    Judson A Brewer;Bernard Khor;Sherri K Vogt;Lisa M Muglia

Frequent Co-Authors

Craig H. Bassing
Craig H. Bassing Children's Hospital of Philadelphia
Frederick W. Alt
Frederick W. Alt Boston Children's Hospital
Steven J. Burakoff
Steven J. Burakoff Icahn School of Medicine at Mount Sinai
André Nussenzweig
André Nussenzweig National Institutes of Health
Laurie Davidson
Laurie Davidson Howard Hughes Medical Institute
Elsa Callen
Elsa Callen National Institutes of Health
David G. Schatz
David G. Schatz Yale University
Jessica K. Tyler
Jessica K. Tyler Cornell University
Michael S. Krangel
Michael S. Krangel Duke University
Richard S. Paules
Richard S. Paules National Institutes of Health

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