What is he best known for?
The fields of study he is best known for:
- Gene
- Internal medicine
- Bacteria
Jan Wehkamp mainly investigates Defensin, Immunology, Microbiology, Inflammatory bowel disease and Antimicrobial peptides.
Jan Wehkamp interconnects Proinflammatory cytokine, Beta-defensin 2, Antibacterial agent and Tumor necrosis factor alpha in the investigation of issues within Defensin.
The various areas that Jan Wehkamp examines in his Microbiology study include Probiotic and Bacteria.
His biological study spans a wide range of topics, including Crohn's disease, Receptor and Ulcerative colitis.
Jan Wehkamp focuses mostly in the field of Crohn's disease, narrowing it down to topics relating to Paneth cell and, in certain cases, Pathogenesis and NOD2.
His Antimicrobial peptides study combines topics from a wide range of disciplines, such as Innate immune system, Intestinal mucosa and Pathology.
His most cited work include:
- Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial (932 citations)
- Reduced Paneth cell α-defensins in ileal Crohn's disease (814 citations)
- NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression. (689 citations)
What are the main themes of his work throughout his whole career to date?
Jan Wehkamp spends much of his time researching Immunology, Microbiology, Defensin, Crohn's disease and Antimicrobial peptides.
His study in Immunology is interdisciplinary in nature, drawing from both Paneth cell and Inflammatory bowel disease.
In his study, which falls under the umbrella issue of Inflammatory bowel disease, Colitis is strongly linked to Ulcerative colitis.
His work on Antimicrobial as part of general Microbiology study is frequently connected to Mucus, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
The study incorporates disciplines such as Proinflammatory cytokine, Molecular biology, Intestinal mucosa and Probiotic in addition to Defensin.
The various areas that he examines in his Crohn's disease study include Gastroenterology, Small intestine and Intensive care medicine.
He most often published in these fields:
- Immunology (51.82%)
- Microbiology (43.18%)
- Defensin (38.64%)
What were the highlights of his more recent work (between 2016-2021)?
- Microbiology (43.18%)
- Disease (12.73%)
- Crohn's disease (31.82%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Microbiology, Disease, Crohn's disease, Antimicrobial and Inflammatory bowel disease.
He has included themes like Experimental colitis and Peptide in his Microbiology study.
His Disease study incorporates themes from Dermatology, Wnt signaling pathway and Tumor necrosis factor alpha, Immunology.
His Immunology research integrates issues from Oral administration and Cancer research.
The concepts of his Antimicrobial study are interwoven with issues in Paneth cell, Cell biology and Bacteria.
His Inflammatory bowel disease research is multidisciplinary, incorporating perspectives in Gastroenterology, Psychiatry and Ulcerative colitis.
Between 2016 and 2021, his most popular works were:
- Intestinal Barrier Function and the Gut Microbiome Are Differentially Affected in Mice Fed a Western-Style Diet or Drinking Water Supplemented with Fructose (58 citations)
- Ubiquitously expressed Human Beta Defensin 1 (hBD1) forms bacteria-entrapping nets in a redox dependent mode of action. (39 citations)
- Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments. (29 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- Immune system
His primary areas of investigation include Crohn's disease, Inflammatory bowel disease, Antimicrobial peptides, Internal medicine and Ulcerative colitis.
The study incorporates disciplines such as Surgery, Endoscopy and Natural course in addition to Crohn's disease.
His Inflammatory bowel disease study combines topics from a wide range of disciplines, such as Concomitant and Colitis.
His Antimicrobial peptides research is multidisciplinary, relying on both Defensin, Paneth cell, Immunology and Cell biology.
His study in Defensin is interdisciplinary in nature, drawing from both Lipopolysaccharide, Innate immune system and Akkermansia.
Jan Wehkamp combines subjects such as Gastroenterology and Endocrinology with his study of Internal medicine.
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