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Manolis Pasparakis

Manolis Pasparakis

University of Cologne
Germany

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Biology and Biochemistry
Germany
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
106
Citations
49809
World Ranking
1139
National Ranking
75

Medicine

D-Index
106
Citations
49824
World Ranking
6436
National Ranking
365

Manolis Pasparakis publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Manolis Pasparakis sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 265 publications — 71st percentile

71% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Manolis Pasparakis D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Manolis Pasparakis sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 106 D-Index — 94th percentile

94% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Germany Leader Award
  • 2025 - Research.com Biology and Biochemistry in Germany Leader Award
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Manolis Pasparakis is affiliated with the University of Cologne in Germany. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology. Within these broad disciplines, their work specifically addresses molecular biology, immunology, cancer research, epidemiology, and oncology.

The scientist's research topics focus on interferon and immune responses, cell death mechanisms and regulation, NF-κB signaling pathways, immune response and inflammation, RNA regulation and disease, inflammasome and immune disorders, and RNA research and splicing.

Manolis Pasparakis has published extensively in several prominent scientific venues. Frequent publication venues include:

  • Nature
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Immunity
  • The Journal of Experimental Medicine

Some of their recent papers are:

  • "Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation" (2020) published in Nature
  • "FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells" (2020) published in Immunity
  • "The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells" (2021) published in Nature Neuroscience
  • "Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation" (2020) published in Nature Communications
  • "ADAR1 averts fatal type I interferon induction by ZBP1" (2022) published in Nature

In their scientific collaborations, Manolis Pasparakis has frequently co-authored with:

  • Laurens Wachsmuth
  • Robin Schwarzer
  • Hamid Kashkar
  • Huipeng Jiao
  • Vangelis Kondylis

Manolis Pasparakis has been recognized with the membership of the European Molecular Biology Organization (EMBO).

Best Publications

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Necroptosis and its role in inflammation

    Manolis Pasparakis;Peter Vandenabeele

  • Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies.

    Dimitris Kontoyiannis;Manolis Pasparakis;Theresa Torres Pizarro;Fabio Cominelli

  • Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

    Yumiko Imai;Keiji Kuba;Keiji Kuba;G. Greg Neely;Rubina Yaghubian-Malhami

  • Epithelial NEMO links innate immunity to chronic intestinal inflammation

    Arianna Nenci;Christoph Becker;Andy Wullaert;Ralph Gareus

  • Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response.

    M Pasparakis;L Alexopoulou;V Episkopou;G Kollias

  • Synchronized renal tubular cell death involves ferroptosis

    Andreas Linkermann;Rachid Skouta;Nina Himmerkus;Shrikant R. Mulay

  • Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis.

    Robert J. Moore;David M. Owens;Gordon Stamp;Caroline Arnott

  • Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis

    Melanie Fritsch;Saskia D. Günther;Robin Schwarzer;Marie-Christine Albert

  • Mechanisms regulating skin immunity and inflammation

    Manolis Pasparakis;Ingo Haase;Frank O. Nestle

  • SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis.

    Fumiyo Ikeda;Yonathan Lissanu Deribe;Sigrid S. Skånland;Benjamin Stieglitz

  • Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma

    Tom Luedde;Tom Luedde;Naiara Beraza;Vasileios Kotsikoris;Geert van Loo

  • FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation

    Patrick-Simon Welz;Andy Wullaert;Katerina Vlantis;Vangelis Kondylis

  • Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer.

    Daniel Schramek;Andreas Leibbrandt;Verena Sigl;Lukas Kenner

  • Regulation of tissue homeostasis by NF-κB signalling: implications for inflammatory diseases

    Manolis Pasparakis

  • NF-κB in the regulation of epithelial homeostasis and inflammation.

    Andy Wullaert;Marion C Bonnet;Manolis Pasparakis

  • NEMO/IKKγ-Deficient Mice Model Incontinentia Pigmenti

    Marc Schmidt-Supprian;Wilhelm Bloch;Gilles Courtois;Klaus Addicks

  • TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2

    Manolis Pasparakis;Gilles Courtois;Martin Hafner;Martin Hafner;Marc Schmidt-Supprian;Marc Schmidt-Supprian

  • RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

    Marius Dannappel;Katerina Vlantis;Snehlata Kumari;Apostolos Polykratis

  • RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS.

    Yasushi Ito;Dimitry Ofengeim;Ayaz Najafov;Sudeshna Das

Frequent Co-Authors

George Kollias
George Kollias National and Kapodistrian University of Athens
Geert van Loo
Geert van Loo Ghent University
Klaus Rajewsky
Klaus Rajewsky Max Delbrück Center for Molecular Medicine
Michelle A. Kelliher
Michelle A. Kelliher University of Massachusetts Chan Medical School
Marc Schmidt-Supprian
Marc Schmidt-Supprian Technical University of Munich
Christian Trautwein
Christian Trautwein RWTH Aachen University
Lena Alexopoulou
Lena Alexopoulou Centre d’Immunologie de Marseille-Luminy
George Kassiotis
George Kassiotis The Francis Crick Institute
John Silke
John Silke Walter and Eliza Hall Institute of Medical Research
Peter Vandenabeele
Peter Vandenabeele Ghent University

External Links

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Related Online Degrees & Career Pathways

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Each of these online pathways allows students to build on their biology or biochemistry background, gaining practical skills and qualifications for in-demand roles across the healthcare sector.

Best Scientists Citing Manolis Pasparakis

George Kollias

George Kollias

National and Kapodistrian University of Athens

Publications: 98

Peter Vandenabeele

Peter Vandenabeele

Ghent University

Publications: 96

Sergei A. Nedospasov

Sergei A. Nedospasov

Lomonosov Moscow State University

Publications: 93

Michael Karin

Michael Karin

University of California, San Diego

Publications: 84

John Silke

John Silke

Walter and Eliza Hall Institute of Medical Research

Publications: 84

Lorenzo Galluzzi

Lorenzo Galluzzi

Cornell University

Publications: 72

Mathias Heikenwalder

Mathias Heikenwalder

German Cancer Research Center

Publications: 68

James M. Murphy

James M. Murphy

Walter and Eliza Hall Institute of Medical Research

Publications: 58

Christian Trautwein

Christian Trautwein

RWTH Aachen University

Publications: 58

Josef M. Penninger

Josef M. Penninger

University of British Columbia

Publications: 57

Guido Kroemer

Guido Kroemer

Université Paris Cité

Publications: 54

Geert van Loo

Geert van Loo

Ghent University

Publications: 54

Rudi Beyaert

Rudi Beyaert

Ghent University

Publications: 50

Markus F. Neurath

Markus F. Neurath

University of Erlangen-Nuremberg

Publications: 49

Kazuhiro Iwai

Kazuhiro Iwai

Kyoto University

Publications: 48

Christoph J. Binder

Christoph J. Binder

Medical University of Vienna

Publications: 48

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