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Molecular Biology

D-Index
63
Citations
20730
World Ranking
1779
National Ranking
142

Overview

Neil D. Perkins is affiliated with Newcastle University in the United Kingdom. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a significant focus on Medicine.

The scientist's work covers a range of subfields including Molecular Biology, Cancer Research, Cell Biology, Genetics, and Dermatology. The main topics addressed in their publications include NF-κB Signaling Pathways, DNA Repair Mechanisms, CRISPR and Genetic Engineering, Endoplasmic Reticulum Stress and Disease, Cell Death Mechanisms and Regulation, Cancer, Hypoxia, and Metabolism, and RNA Modifications and Cancer.

Neil D. Perkins has contributed to several frequent publication venues, notably:

  • Biochemical Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Cancer
  • Communications Biology
  • International Journal of Molecular Sciences

Their recent papers include the following:

  • "Age-associated mitochondrial DNA mutations cause metabolic remodeling that contributes to accelerated intestinal tumorigenesis" (2020), published in Nature Cancer
  • "Centrosome dysfunction associated with somatic expression of the synaptonemal complex protein TEX12" (2021), published in Communications Biology
  • "Temporal modulation of the NF-κB RelA network in response to different types of DNA damage" (2021), published in Biochemical Journal
  • "A Cell-Based Optimised Approach for Rapid and Efficient Gene Editing of Human Pluripotent Stem Cells" (2023), published in International Journal of Molecular Sciences
  • "A Thermally Reformable Protein Polymer" (2020), published in Chem

The scientist frequently collaborates with several researchers, including:

  • Jill V. Hunter
  • A. Campbell
  • Philip Brownridge
  • Claire E. Eyers
  • Saimir Luli

Best Publications

  • Integrating cell-signalling pathways with NF-kappaB and IKK function.

    Neil D. Perkins

  • The diverse and complex roles of NF-κB subunits in cancer

    Neil D. Perkins

  • Regulation of NF-κB by Cyclin-Dependent Kinases Associated with the p300 Coactivator

    Neil D. Perkins;Lisa K. Felzien;Jonathan C. Betts;Kwanyee Leung

  • Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway

    N D Perkins

  • Transcriptional Cross Talk between NF-κB and p53

    Gill A. Webster;Neil D. Perkins

  • Good cop, bad cop: the different faces of NF-κB

    N D Perkins;T D Gilmore

  • A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation.

    N.D. Perkins;N.L. Edwards;C.S. Duckett;A.B. Agranoff

  • P300 transcriptional repression is mediated by SUMO modification.

    David Girdwood;Donna Bumpass;Owen A Vaughan;Alison Thain

  • Active Repression of Antiapoptotic Gene Expression by RelA(p65) NF-κB

    Kirsteen J Campbell;Sonia Rocha;Neil D Perkins

  • Transcriptional profiling of the LPS induced NF-κB response in macrophages

    Omar Sharif;Viacheslav N Bolshakov;Viacheslav N Bolshakov;Stephanie Raines;Peter Newham

  • The Rel/NF-κB family: friend and foe

    Neil D Perkins

  • Cloning of an NF-κB subunit which stimulates HIV transcription in synergy with p65

    Roland M. Schmid;Neil D. Perkins;Colin S. Duckett;Philip C. Andrews

  • SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1.

    Toula Bouras;Maofu Fu;Anthony A. Sauve;Fang Wang

  • NF-κB: tumor promoter or suppressor?

    Neil D. Perkins

  • p53 Represses Cyclin D1 Transcription through Down Regulation of Bcl-3 and Inducing Increased Association of the p52 NF-κB Subunit with Histone Deacetylase 1

    Sonia Rocha;Anthea M. Martin;David W. Meek;Neil D. Perkins

  • Role of the p21 cyclin-dependent kinase inhibitor in limiting intimal cell proliferation in response to arterial injury.

    Zhi Yong Yang;Robert D. Simari;Neil D. Perkins;Hong San

  • NFKB1: a suppressor of inflammation, ageing and cancer.

    Tyrell Cartwright;Neil D. Perkins;Caroline L. Wilson

  • An interaction between the DNA-binding domains of RelA(p65) and Sp1 mediates human immunodeficiency virus gene activation.

    Neil D. Perkins;Adam B. Agranoff;Erica Pascal;Gary J. Nabel

  • Distinct combinations of NF-kappa B subunits determine the specificity of transcriptional activation.

    Neil D. Perkins;Roland M. Schmid;Colin S. Duckett;Kwanyee Leung

  • The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor

    Gaynor J Bates;Samantha M Nicol;Brian J Wilson;Anne-Marie F Jacobs

Frequent Co-Authors

Gary J. Nabel
Gary J. Nabel ModeX Therapeutics
Sonia Rocha
Sonia Rocha University of Liverpool
Fiona Oakley
Fiona Oakley Newcastle University
Colin S. Duckett
Colin S. Duckett Duke University School of Medicine
Jill Manthorpe
Jill Manthorpe King's College London
Derek A. Mann
Derek A. Mann Newcastle University
Parmjit S. Jat
Parmjit S. Jat University College London
Igor B. Roninson
Igor B. Roninson University of South Carolina
Jorge Caamano
Jorge Caamano University of Birmingham
Zhi-Yong Yang
Zhi-Yong Yang ModeX Therapeutics LLC

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