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D-Index & Metrics

Molecular Biology

D-Index
49
Citations
9950
World Ranking
2622
National Ranking
203

Overview

Fiona Oakley is affiliated with Newcastle University in the United Kingdom and has published extensively in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans several subfields including Epidemiology, Molecular Biology, Immunology, Hepatology, and Cancer Research.

The main focus of their work includes Liver Disease Diagnosis and Treatment, Liver physiology and pathology, Liver Diseases and Immunity, Endoplasmic Reticulum Stress and Disease, Cancer, Lipids, and Metabolism, Lipid metabolism and biosynthesis, and 3D Printing in Biomedical Research.

Frequent coauthors collaborating with Oakley include Derek A. Mann, Jack Leslie, Amy Collins, Lee A. Borthwick, and Jelena Mann.

Oakley has contributed multiple papers to notable journals, with selected recent publications listed below:

  • Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: A systematic review and meta-analysis, 2021, Journal of Hepatology
  • Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner, 2021, The EMBO Journal
  • An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD), 2024, Nature Metabolism
  • Performance of non-invasive tests and histology for the prediction of clinical outcomes in patients with non-alcoholic fatty liver disease: an individual participant data meta-analysis, 2023, The Lancet. Gastroenterology & hepatology
  • Lipid Remodeling in Hepatocyte Proliferation and Hepatocellular Carcinoma, 2020, Hepatology

The most frequent publication venues for Oakley's work include the Journal of Hepatology, bioRxiv (Cold Spring Harbor Laboratory), Nature Metabolism, Hepatology, and Scientific Reports.

Best Publications

  • Chronic inflammation induces telomere dysfunction and accelerates ageing in mice

    Diana Jurk;Caroline Wilson;Joao F. Passos;Fiona Oakley

  • The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis

    AM Elsharkawy;F Oakley;DA Mann

  • Nonalcoholic Fatty Liver Disease: Pathogenesis and Disease Spectrum

    Timothy Hardy;Fiona Oakley;Quentin M. Anstee;Christopher P. Day

  • MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis.

    Jelena Mann;David C.K. Chu;Aidan Maxwell;Fiona Oakley

  • Inhibition of inhibitor of κB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis

    Fiona Oakley;Muriel Meso;John P. Iredale;Karen Green

  • Multigenerational epigenetic adaptation of the hepatic wound-healing response

    Müjdat Zeybel;Timothy Hardy;Yi K Wong;John C Mathers

  • Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis

    J. Mann;F. Oakley;F. Akiboye;A. Elsharkawy

  • Nuclear factor-kappaB1: regulation and function.

    Silvia Gaspar Pereira;Fiona Oakley

  • A Role for Serotonin (5-HT) in Hepatic Stellate Cell Function and Liver Fibrosis

    Richard G. Ruddell;Fiona Oakley;Ziafat Hussain;Irene Yeung

  • Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: A systematic review and meta-analysis

    Emmanuel Anandraj Selvaraj;Ferenc Emil Mózes;Arjun Narayan Ajmer Jayaswal;Mohammad Hadi Zafarmand

  • Stimulating healthy tissue regeneration by targeting the 5-HT₂B receptor in chronic liver disease.

    Mohammad R Ebrahimkhani;Fiona Oakley;Lindsay B Murphy;Jelena Mann

  • Hepatocytes Express Nerve Growth Factor during Liver Injury: Evidence for Paracrine Regulation of Hepatic Stellate Cell Apoptosis

    Fiona Oakley;Nathan Trim;Christothea M Constandinou;Weilan Ye

  • The NF-κB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes

    Ahmed M. Elsharkawy;Fiona Oakley;Feng Lin;Graham Packham

  • NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma.

    C. L. Wilson;D. Jurk;N. Fullard;P. Banks

  • A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse

    Anna Moles;Lindsay Murphy;Caroline L. Wilson;Jayashree Bagchi Chakraborty

  • Mechanisms and Biomarkers of Apoptosis in Liver Disease and Fibrosis

    Jayashree Bagchi Chakraborty;Fiona Oakley;Meagan J. Walsh

  • Angiotensin II Activates IκB Kinase Phosphorylation of RelA at Ser536 to Promote Myofibroblast Survival and Liver Fibrosis

    Fiona Oakley;Victoria Teoh;Gemma Ching–A–Sue;Ramon Bataller

  • Nuclear Factor-κB1 (p50) Limits the Inflammatory and Fibrogenic Responses to Chronic Injury

    Fiona Oakley;Jelena Mann;Sarah Nailard;David E. Smart

  • Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner.

    Anthony Lagnado;Jack Leslie;Marie Helene Ruchaud-Sparagano;Stella Victorelli

  • Pathogenesis of FOLFOX induced sinusoidal obstruction syndrome in a murine chemotherapy model

    S.M. Robinson;J. Mann;A. Vasilaki;J. Mathers

Frequent Co-Authors

Derek A. Mann
Derek A. Mann Newcastle University
Alastair D. Burt
Alastair D. Burt Newcastle University
Quentin M. Anstee
Quentin M. Anstee Newcastle University
Sylvia Knapp
Sylvia Knapp Medical University of Vienna
Neil D. Perkins
Neil D. Perkins Newcastle University
John P. Iredale
John P. Iredale University of Bristol
João F. Passos
João F. Passos Mayo Clinic
Antonio Vidal-Puig
Antonio Vidal-Puig University of Cambridge
Hidekazu Tsukamoto
Hidekazu Tsukamoto University of Southern California
Luis Bujanda
Luis Bujanda University of the Basque Country

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