What is he best known for?
The fields of study he is best known for:
- Internal medicine
- Gene
- Cancer
Adipose tissue, Senolytic, Internal medicine, Endocrinology and Senescence are his primary areas of study.
His biological study spans a wide range of topics, including Inflammation, Proinflammatory cytokine, Cell aging and Longevity.
The various areas that James L. Kirkland examines in his Senolytic study include Apoptosis, Navitoclax, Cancer research and Immunology.
His primary area of study in Internal medicine is in the field of Disease.
James L. Kirkland combines subjects such as Progenitor cell, Gene expression and Cellular differentiation with his study of Endocrinology.
His Senescence research incorporates themes from Signal transduction and Ageing.
His most cited work include:
- Clearance of p16 Ink4a -positive senescent cells delays ageing-associated disorders (1845 citations)
- Cellular senescence and the senescent secretory phenotype: therapeutic opportunities. (861 citations)
- The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs (759 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Internal medicine, Endocrinology, Adipose tissue, Senescence and Senolytic.
His Internal medicine research includes themes of Diabetes mellitus and Gene expression.
His work carried out in the field of Endocrinology brings together such families of science as Proinflammatory cytokine and Cellular differentiation.
His work in Adipose tissue addresses subjects such as Inflammation, which are connected to disciplines such as Immune system and Signal transduction.
Many of his research projects under Senescence are closely connected to Mechanism with Mechanism, tying the diverse disciplines of science together.
His work deals with themes such as Navitoclax, Cancer research and Clinical trial, Bioinformatics, which intersect with Senolytic.
He most often published in these fields:
- Internal medicine (45.89%)
- Endocrinology (41.99%)
- Adipose tissue (31.17%)
What were the highlights of his more recent work (between 2018-2021)?
- Senolytic (20.78%)
- Senescence (27.71%)
- Internal medicine (45.89%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Senolytic, Senescence, Internal medicine, Endocrinology and Cancer research.
He has researched Senolytic in several fields, including Clinical trial, Bioinformatics, Inflammation, Disease and Fibrosis.
His Senescence study integrates concerns from other disciplines, such as Phenotype, Andrology, Adipose tissue and Telomere.
His Adipose tissue research includes elements of Biomarker and Renal fibrosis.
James L. Kirkland interconnects Diabetes mellitus and Gastroenterology in the investigation of issues within Internal medicine.
His Endocrinology research is multidisciplinary, relying on both PI3K/AKT/mTOR pathway and Stem cell.
Between 2018 and 2021, his most popular works were:
- Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study. (284 citations)
- Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease. (195 citations)
- Sarcopenia: Aging-Related Loss of Muscle Mass and Function. (187 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- Cancer
James L. Kirkland mainly investigates Senolytic, Senescence, Internal medicine, Phenotype and Adipose tissue.
The study incorporates disciplines such as Cancer research, Clinical trial, Bioinformatics and Disease in addition to Senolytic.
His work carried out in the field of Senescence brings together such families of science as Immunology, Hyperoxia and Osteoporosis.
His Internal medicine research integrates issues from Ex vivo and Endocrinology.
James L. Kirkland interconnects Cell biology and Ageing in the investigation of issues within Phenotype.
His study in Adipose tissue is interdisciplinary in nature, drawing from both Inflammation, Soft tissue, Asymptomatic and Diabetes mellitus.
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