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Biology and Biochemistry

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111
Citations
50520
World Ranking
929
National Ranking
579

Medicine

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112
Citations
50983
World Ranking
5116
National Ranking
2766

Overview

Richard A. Miller is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily focuses on medicine and biochemistry, genetics, and molecular biology, with significant work also spanning subfields such as molecular biology, physiology, aging, epidemiology, and surgery.

The scientist has been notably active in exploring themes related to genetics, aging, and longevity in model organisms, adipose tissue and metabolism, pancreatic function and diabetes, circadian rhythm and melatonin, mitochondrial function and pathology, metabolism, diabetes, and cancer, as well as diabetes treatment and management.

Frequent coauthors include Randy Strong, James F. Nelson, David E. Harrison, Peter C. Reifsnyder, and Nadia Rosenthal. These collaborations have contributed to a body of work distributed across several publication venues.

Preferred venues for publication have been:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • GeroScience
  • Aging Cell
  • Aging
  • The Journals of Gerontology Series A

Selected recent papers include:

  • Muribaculaceae Genomes Assembled from Metagenomes Suggest Genetic Drivers of Differential Response to Acarbose Treatment in Mice, 2021, mSphere
  • Distinct longevity mechanisms across and within species and their association with aging, 2023, Cell
  • Canagliflozin extends life span in genetically heterogeneous male but not female mice, 2020, JCI Insight
  • Rapamycin-mediated mouse lifespan extension: Late-life dosage regimes with sex-specific effects, 2020, Aging Cell
  • 17-a-estradiol late in life extends lifespan in aging UM-HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex, 2021, Aging Cell

Best Publications

  • Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

    David E. F. Harrison;Randy Strong;Zelton Dave Sharp;James F Nelson

  • The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

    Lee A. Honigberg;Ashley M. Smith;Mint Sirisawad;Erik Verner

  • The Aging Immune System: Primer and Prospectus

    Richard A. Miller

  • Treatment of B-Cell Lymphoma with Monoclonal Anti-Idiotype Antibody

    Richard A. Miller;David G. Maloney;Roger Warnke;Ronald Levy

  • Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice

    Richard A. Miller;Richard A. Miller;David E. Harrison;C. M. Astle;Joseph A. Baur

  • Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance

    Richard A. Miller;Gretchen Buehner;Yayi Chang;James M. Harper

  • Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production

    Kevin Flurkey;John Papaconstantinou;Richard A. Miller;David E. Harrison

  • mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

    Nicolás Herranz;Suchira Gallage;Massimiliano Mellone;Torsten Wuestefeld

  • Rapamycin slows aging in mice.

    John E. Wilkinson;Lisa Burmeister;Susan V. Brooks;Chi Chao Chan

  • Vitamin E supplementation enhances cell-mediated immunity in healthy elderly subjects.

    S. N. Meydani;M. P. Barklund;S. Liu;M. Meydani

  • Neurocognitive Function and Progression in Patients With Brain Metastases Treated With Whole-Brain Radiation and Motexafin Gadolinium: Results of a Randomized Phase III Trial

    Christina A. Meyers;Jennifer A. Smith;Andrea Bezjak;Minesh P. Mehta

  • A clinical trial of anti-idiotype therapy for B cell malignancy.

    Timothy C. Meeker;James Lowder;David G. Maloney;Richard A. Miller

  • Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction

    Richard A. Miller;David E. Harrison;Clinton M. Astle;Elizabeth Fernandez

  • Survival and Neurologic Outcomes in a Randomized Trial of Motexafin Gadolinium and Whole-Brain Radiation Therapy in Brain Metastases

    Minesh P. Mehta;Patrick Rodrigus;C. H J Terhaard;Aroor Rao

  • Extending the lifespan of long-lived mice.

    Andrzej Bartke;J. Chris Wright;Julie A. Mattison;Donald K. Ingram

  • Acarbose, 17‐α‐estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males

    David E. Harrison;Randy Strong;David B. Allison;Bruce N. Ames

  • Aging and immune function

    Richard A. Miller

  • Monoclonal antibody therapeutic trials in seven patients with T-cell lymphoma

    Richard A. Miller;Allan R. Oseroff;Paul T. Stratte;Ronald Levy

  • Texaphyrins: new drugs with diverse clinical applications in radiation and photodynamic therapy.

    Jonathan L Sessler;Richard A Miller

  • Colorectal cancer screening: prospects for molecular stool analysis

    R. Justin Davies;Richard Miller;Nicholas Coleman

Frequent Co-Authors

Jonathan L. Sessler
Jonathan L. Sessler The University of Texas at Austin
David E. Harrison
David E. Harrison Jackson Laboratory
Vadim N. Gladyshev
Vadim N. Gladyshev Brigham and Women's Hospital
John J. Kopchick
John J. Kopchick Ohio University
Vladimír Král
Vladimír Král University of Chemistry and Technology
Martin A. Javors
Martin A. Javors The University of Texas Health Science Center at San Antonio
Anthony Harriman
Anthony Harriman Newcastle University
Minesh P. Mehta
Minesh P. Mehta University of Maryland, Baltimore
Arlan Richardson
Arlan Richardson University of Oklahoma Health Sciences Center
David B. Lombard
David B. Lombard University of Michigan–Ann Arbor

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