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Medicine

D-Index
119
Citations
62970
World Ranking
3848
National Ranking
2106

Overview

Rafael de Cabo is affiliated with the National Institutes of Health in the United States. Their research spans a broad set of topics within medicine and biochemistry, genetics, and molecular biology, with a focus on physiology, molecular biology, aging, endocrine and autonomic systems, and geriatrics and gerontology.

Their main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these fields, Rafael de Cabo has concentrated on several subfields of study such as:

  • Physiology
  • Molecular Biology
  • Aging
  • Endocrine and Autonomic Systems
  • Geriatrics and Gerontology

The primary research topics covered in their publications involve:

  • Adipose Tissue and Metabolism
  • Diet and metabolism studies
  • Genetics, Aging, and Longevity in Model Organisms
  • Dietary Effects on Health
  • Circadian rhythm and melatonin
  • Epigenetics and DNA Methylation
  • Mitochondrial Function and Pathology

Rafael de Cabo has contributed to multiple scientific papers, including recent publications such as:

  • The carbohydrate-insulin model: a physiological perspective on the obesity pandemic (2021) published in American Journal of Clinical Nutrition
  • Age-induced accumulation of methylmalonic acid promotes tumour progression (2020) published in Nature
  • Branched chain amino acids, aging and age-related health (2020) published in Ageing Research Reviews
  • Restoration of energy homeostasis by SIRT6 extends healthy lifespan (2021) published in Nature Communications
  • Untangling Determinants of Enhanced Health and Lifespan through a Multi-omics Approach in Mice (2020) published in Cell Metabolism

The scientist frequently collaborates with several co-authors, including:

  • Michel Bernier
  • Luigi Ferrucci
  • Nathan L. Price
  • Miguel A. Aon
  • Sarah J. Mitchell

Rafael de Cabo's work is regularly published in journals such as:

  • Innovation in Aging
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • GeroScience
  • The Journals of Gerontology Series A

Best Publications

  • Resveratrol improves health and survival of mice on a high-calorie diet

    Joseph A. Baur;Kevin J. Pearson;Nathaniel O Price;Hamish A. Jamieson

  • Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase.

    Haim Y. Cohen;Christine Miller;Kevin J. Bitterman;Nathan R. Wall

  • SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

    Nathan L. Price;Ana P. Gomes;Alvin J.Y. Ling;Filipe V. Duarte

  • Effects of Intermittent Fasting on Health, Aging, and Disease

    Rafael de Cabo;Mark P Mattson

  • Metformin improves healthspan and lifespan in mice

    Alejandro Martin-Montalvo;Evi M. Mercken;Sarah J. Mitchell;Sarah J. Mitchell;Sarah J. Mitchell;Hector H. Palacios

  • Declining NAD + Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging

    Ana P. Gomes;Ana P. Gomes;Nathan L. Price;Alvin J.Y. Ling;Javid Moslehi

  • Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span.

    Kevin J. Pearson;Joseph A. Baur;Kaitlyn N. Lewis;Leonid Peshkin

  • Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study

    Julie A. Mattison;George S. Roth;T. Mark Beasley;Edward M. Tilmont

  • Nutrient-Sensitive Mitochondrial NAD+ Levels Dictate Cell Survival

    Hongying Yang;Tianle Yang;Joseph A. Baur;Evelyn Perez

  • Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice

    Richard A. Miller;Richard A. Miller;David E. Harrison;C. M. Astle;Joseph A. Baur

  • Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake

    R. Michael Anson;Zhihong Guo;Rafael de Cabo;Titilola Iyun

  • Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans.

    Jaime Guevara-Aguirre;Priya Balasubramanian;Marco Guevara-Aguirre;Min Wei

  • Caloric restriction improves health and survival of rhesus monkeys.

    Julie A. Mattison;Ricki J. Colman;T. Mark Beasley;T. Mark Beasley;David B. Allison

  • Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency.

    G. López-Lluch;N. Hunt;B. Jones;M. Zhu

  • Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy

    Changhan Lee;Lizzia Raffaghello;Sebastian Brandhorst;Sebastian Brandhorst;Fernando M. Safdie

  • The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth

    Ron Firestein;Gil Blander;Shaday Michan;Philipp Oberdoerffer

  • Interventions to Slow Aging in Humans: Are We Ready?

    Valter D. Longo;Adam Antebi;Andrzej Bartke;Nir Barzilai

  • Mechanisms of vascular aging: new perspectives.

    Zoltan Ungvari;Gabor Kaley;Rafael de Cabo;William E. Sonntag

  • The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance

    Changhan Lee;Jennifer Zeng;Brian G. Drew;Tamer Sallam

  • Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2.

    Zoltan I Ungvari;Zsolt Bagi;Attila Feher;Fabio A. Recchia

Frequent Co-Authors

Michel Bernier
Michel Bernier National Institutes of Health
David G. Le Couteur
David G. Le Couteur University of Sydney
Sarah N. Hilmer
Sarah N. Hilmer University of Sydney
Donald K. Ingram
Donald K. Ingram Louisiana State University
David A. Sinclair
David A. Sinclair Harvard University
Plácido Navas
Plácido Navas Pablo de Olavide University
José M. Villalba
José M. Villalba University of Córdoba
Zoltan Ungvari
Zoltan Ungvari University of Oklahoma Health Sciences Center
Anna Csiszar
Anna Csiszar University of Oklahoma Health Sciences Center
Kevin G. Becker
Kevin G. Becker National Institutes of Health

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