His primary scientific interests are in Biochemistry, Mitochondrion, Coenzyme Q – cytochrome c reductase, Cell biology and Oxidative stress. His biological study spans a wide range of topics, including Calorie restriction, Autophagy, Mitophagy, Reactive oxygen species and Proteostasis. Plácido Navas has researched Coenzyme Q – cytochrome c reductase in several fields, including Electron transport chain, Coenzyme Q10, Antioxidant and Mitochondrial respiratory chain.
His work carried out in the field of Cell biology brings together such families of science as Apoptosis, Molecular biology and Mitochondrial permeability transition pore. A component of his Oxidative stress study involves Endocrinology and Internal medicine. His work carried out in the field of Internal medicine brings together such families of science as Protein kinase A, Coactivator, Drosophila melanogaster, Caloric restriction mimetic and SRT1720.
His main research concerns Biochemistry, Coenzyme Q – cytochrome c reductase, Internal medicine, Mitochondrion and Endocrinology. As a part of the same scientific family, he mostly works in the field of Biochemistry, focusing on Redox and, on occasion, Ferricyanide. His Coenzyme Q – cytochrome c reductase study incorporates themes from Antioxidant, Cofactor, Coenzyme Q10, Mitochondrial respiratory chain and Respiratory chain.
Plácido Navas specializes in Internal medicine, namely Oxidative stress. His work focuses on many connections between Mitochondrion and other disciplines, such as Reactive oxygen species, that overlap with his field of interest in Oxidative phosphorylation. His Endocrinology study frequently links to related topics such as Resveratrol.
His primary areas of investigation include Mitochondrion, Internal medicine, Endocrinology, Coenzyme Q – cytochrome c reductase and Coenzyme Q10. His Mitochondrion research includes themes of Autophagy, Oxidative stress, Disease and Mitochondrial disease. The concepts of his Endocrinology study are interwoven with issues in Offspring, Gene expression and Resveratrol.
His Coenzyme Q – cytochrome c reductase study is concerned with the larger field of Biochemistry. Metabolic pathway is closely connected to Ageing in his research, which is encompassed under the umbrella topic of Biochemistry. When carried out as part of a general Coenzyme Q10 research project, his work on Coenzyme Q10 deficiency is frequently linked to work in Electrochemical detection, therefore connecting diverse disciplines of study.
His primary areas of study are Coenzyme Q – cytochrome c reductase, Mitochondrion, Coenzyme Q10, Biochemistry and Internal medicine. The study incorporates disciplines such as Respiratory chain, Mitochondrial respiratory chain and Mitochondrial disease in addition to Coenzyme Q – cytochrome c reductase. Plácido Navas combines subjects such as Autophagy, Oxidative stress and Proteostasis with his study of Mitochondrion.
His Biochemistry study combines topics in areas such as Biomarker and Ageing. His study on Internal medicine is mostly dedicated to connecting different topics, such as Endocrinology. In the field of Endocrinology, his study on Nephrotic syndrome overlaps with subjects such as Steroid-resistant nephrotic syndrome.
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Resveratrol improves health and survival of mice on a high-calorie diet
Joseph A. Baur;Kevin J. Pearson;Nathaniel O Price;Hamish A. Jamieson.
Nature (2006)
Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain
Esther Lapuente-Brun;Esther Lapuente-Brun;Raquel Moreno-Loshuertos;Rebeca Acín-Pérez;Ana Latorre-Pellicer.
Science (2013)
MITOCHONDRIAL BIOGENESIS AND HEALTHY AGING
Guillermo López-Lluch;Pablo M. Irusta;Placido Navas;Rafael de Cabo.
Experimental Gerontology (2008)
A Mutation in Para-Hydroxybenzoate-Polyprenyl Transferase (COQ2) Causes Primary Coenzyme Q10 Deficiency
Catarina Quinzii;Ali Naini;Leonardo Salviati;Eva Trevisson.
American Journal of Human Genetics (2006)
COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness
Heeringa Sf;Chernin G;Chaki M;Zhou W.
Journal of Clinical Investigation (2011)
Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction
Kevin J. Pearson;Kaitlyn N. Lewis;Nathan L. Price;Joy W. Chang.
Proceedings of the National Academy of Sciences of the United States of America (2008)
Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice
Sarah J. Mitchell;Julio Madrigal-Matute;Morten Scheibye-Knudsen;Morten Scheibye-Knudsen;Evandro Fang.
Cell Metabolism (2016)
Coenzyme Q reductase from liver plasma membrane: purification and role in trans-plasma-membrane electron transport
Jose M. Villalba;Francisco Navarro;Francisco Cordoba;Antonio Serrano.
Proceedings of the National Academy of Sciences of the United States of America (1995)
Mitochondrial ROS Produced via Reverse Electron Transport Extend Animal Lifespan
Filippo Scialò;Ashwin Sriram;Daniel Fernández-Ayala;Nina Gubina.
Cell Metabolism (2016)
Coenzyme Q deficiency triggers mitochondria degradation by mitophagy.
Ángeles Rodríguez-Hernández;Mario D. Cordero;Leonardo Salviati;Rafael Artuch.
Autophagy (2009)
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