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Leonardo Salviati

Leonardo Salviati

D-Index & Metrics

Genetics

D-Index
62
Citations
15923
World Ranking
2964
National Ranking
58

Overview

Leonardo Salviati is affiliated with the University of Padua in Italy and has contributed to research primarily in the fields of Biochemistry, Genetics, and Molecular Biology, with a significant emphasis on Medicine. Their work spans several subfields, including Molecular Biology, Neurology, Genetics, Physiology, and Cellular and Molecular Neuroscience.

The scientist's research topics include:

  • Mitochondrial Function and Pathology
  • Lysosomal Storage Disorders Research
  • Genetic Neurodegenerative Diseases
  • Metabolism and Genetic Disorders
  • Coenzyme Q10 studies and effects
  • RNA regulation and disease
  • Advanced battery technologies research

Salviati has published in a range of venues frequently, such as:

  • Cell Death and Disease
  • International Journal of Neonatal Screening
  • Nature Communications
  • Molecular Genetics and Metabolism Reports
  • European Journal of Human Genetics

Frequent co-authors collaborating with Salviati include María Andrea Desbats, Alberto Burlina, Vincenza Gragnaniello, Chiara Cazzorla, and Daniela Gueraldi.

Among recent papers, key publications include:

  • "The pyruvate kinase activator mitapivat reduces hemolysis and improves anemia in a β-thalassemia mouse model" (2021) published in the Journal of Clinical Investigation
  • "OPA1 drives macrophage metabolism and functional commitment via p65 signaling" (2022) in Cell Death and Differentiation
  • "Deficit of human ornithine aminotransferase in gyrate atrophy: Molecular, cellular, and clinical aspects" (2020) in Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  • "The multiple roles of coenzyme Q in cellular homeostasis and their relevance for the pathogenesis of coenzyme Q deficiency" (2021) in Free Radical Biology and Medicine
  • "Newborn Screening for Fabry Disease in Northeastern Italy: Results of Five Years of Experience" (2021) in Biomolecules

The research responsibilities and outputs of Salviati encompass experimental and clinical aspects of genetic disorders, mitochondrial function, and metabolic diseases, contributing to different molecular and cellular mechanisms underlying these conditions.

Best Publications

  • Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency

    Sara Cogliati;Christian Frezza;Maria Eugenia Soriano;Tatiana Varanita

  • Assessment of mitochondrial respiratory chain enzymatic activities on tissues and cultured cells

    Marco Spinazzi;Alberto Casarin;Vanessa Pertegato;Leonardo Salviati

  • Age-Associated Loss of OPA1 in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence

    Caterina Tezze;Vanina Romanello;Maria Andrea Desbats;Gian Paolo Fadini

  • COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness

    Saskia F. Heeringa;Gil Chernin;Moumita Chaki;Weibin Zhou

  • A Mutation in Para-Hydroxybenzoate-Polyprenyl Transferase (COQ2) Causes Primary Coenzyme Q10 Deficiency

    Catarina Quinzii;Ali Naini;Leonardo Salviati;Eva Trevisson

  • ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption

    Shazia Ashraf;Heon Yung Gee;Stephanie Woerner;Stephanie Woerner;Letian X. Xie

  • Mitochondrial dysfunction in inherited renal disease and acute kidney injury

    Francesco Emma;Giovanni Montini;Samir M. Parikh;Leonardo Salviati

  • DRP1-mediated mitochondrial shape controls calcium homeostasis and muscle mass

    Giulia Favaro;Vanina Romanello;Tatiana Varanita;Maria Andrea Desbats

  • Early coenzyme Q10 supplementation in primary coenzyme Q10 deficiency.

    Giovanni Montini;Cristina Malaventura;Leonardo Salviati

  • Coenzyme Q biosynthesis in health and disease

    Manuel Jesús Acosta;Luis Vazquez Fonseca;Maria Andrea Desbats;Cristina Cerqua

  • Coenzyme Q deficiency triggers mitochondria degradation by mitophagy.

    Ángeles Rodríguez-Hernández;Mario D. Cordero;Leonardo Salviati;Rafael Artuch

  • Genetic bases and clinical manifestations of coenzyme Q10 (CoQ10) deficiency

    Maria Andrea Desbats;Giada Lunardi;Mara Doimo;Eva Trevisson

  • LETM1, deleted in Wolf-Hirschhorn syndrome is required for normal mitochondrial morphology and cellular viability

    Kai Stefan Dimmer;Francesca Navoni;Alberto Casarin;Eva Trevisson

  • The FSHD2 gene SMCHD1 is a modifier of disease severity in families affected by FSHD1.

    Sabrina Sacconi;Richard J.L.F. Lemmers;Judit Balog;Patrick J. van der Vliet

  • Mitochondrial DNA depletion: Mutations in thymidine kinase gene with myopathy and SMA

    M. Mancuso;L. Salviati;L. Salviati;S. Sacconi;S. Sacconi;D. Otaegui

  • Mitochondrial DNA depletion and dGK gene mutations

    Leonardo Salviati;Sabrina Sacconi;Michelangelo Mancuso;Michelangelo Mancuso;David Otaegui

  • Reactive oxygen species, oxidative stress, and cell death correlate with level of CoQ10 deficiency

    Catarina M. Quinzii;Luis C. López;Robert W. Gilkerson;Beatriz Dorado

  • Respiratory chain dysfunction and oxidative stress correlate with severity of primary CoQ10 deficiency.

    Catarina M. Quinzii;Luis C. López;Jakob Von-Moltke;Ali Naini

  • Cytochrome c Oxidase Deficiency Due to a Novel SCO2 Mutation Mimics Werdnig-Hoffmann Disease

    Leonardo Salviati;Sabrina Sacconi;Minerva M. Rasalan;David F. Kronn

  • Missense mutation of the COQ2 gene causes defects of bioenergetics and de novo pyrimidine synthesis

    José M. López-Martín;Leonardo Salviati;Eva Trevisson;Giovanni Montini

Frequent Co-Authors

Plácido Navas
Plácido Navas Pablo de Olavide University
Salvatore DiMauro
Salvatore DiMauro Columbia University
Michio Hirano
Michio Hirano Columbia University
Rafael Artuch
Rafael Artuch Instituto de Salud Carlos III
Giuseppe Basso
Giuseppe Basso University of Padua
Corrado Angelini
Corrado Angelini University of Padua
Romano Tenconi
Romano Tenconi University of Padua
Friedhelm Hildebrandt
Friedhelm Hildebrandt Boston Children's Hospital
Eduardo Bonilla
Eduardo Bonilla Columbia University
Luca Scorrano
Luca Scorrano University of Padua

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