World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
112
Citations
39306
World Ranking
5196
National Ranking
2808

Samuel Refetoff publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Samuel Refetoff sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 589 publications — 70th percentile

70% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Samuel Refetoff D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Samuel Refetoff sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 112 D-Index — 75th percentile

75% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Samuel Refetoff is affiliated with the University of Chicago in the United States. Their research primarily focuses on fields related to Medicine, with significant contributions to Biochemistry, Genetics, and Molecular Biology. Within these main fields, their subfields of study include Endocrinology, Diabetes and Metabolism, Molecular Biology, Genetics, Endocrine and Autonomic Systems, and Cell Biology.

The scientist's work encompasses a range of topics centered around thyroid-related conditions and their underlying mechanisms. Major research topics include:

  • Thyroid Disorders and Treatments
  • Growth Hormone and Insulin-like Growth Factors
  • Genetics and Neurodevelopmental Disorders
  • Thyroid Cancer Diagnosis and Treatment
  • Neuroscience of respiration and sleep
  • Ion channel regulation and function
  • Erythrocyte Function and Pathophysiology

Samuel Refetoff has collaborated extensively with several frequent co-authors, including Xiao-Hui Liao, Alexandra M. Dumitrescu, Roy E. Weiss, Peter Arvan, and Sabine Costagliola. These collaborations have contributed to a steady output of research publications in several academic venues.

Their publications have appeared most frequently in the following journals and proceedings:

  • Thyroid
  • Journal of the Endocrine Society
  • Endocrine Abstracts
  • JCI Insight
  • bioRxiv (Cold Spring Harbor Laboratory)

Some recent notable papers authored or co-authored by Samuel Refetoff include:

  • "SWI/SNF Complex Mutations Promote Thyroid Tumor Progression and Insensitivity to Redifferentiation Therapies," Cancer Discovery, 2020
  • "Resistance to Thyroid Hormone Beta: A Focused Review," Frontiers in Endocrinology, 2021
  • "Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut," Immunity, 2023
  • "Increased Hepatic Fat Content in Patients with Resistance to Thyroid Hormone Beta," Thyroid, 2020
  • "Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism," Nature Communications, 2022

Throughout their career, Refetoff has published extensively on thyroid hormone mechanisms and related metabolic phenomena. Their research spans molecular biology pathways, clinical endocrinology, and aspects of cellular stress responses. This broad range connects to both fundamental biology and potential clinical applications, especially regarding thyroid hormone resistance and thyroid cancer.

Samuel Refetoff is recognized as a member of the Association of American Physicians, an affiliation reflecting professional engagement within the medical research community.

Best Publications

  • The Syndromes of Resistance to Thyroid Hormone

    Samuel Refetoff;Roy E. Weiss;Stephen J. Usala

  • A novel syndrome combining thyroid and neurological abnormalities is associated with mutations in a monocarboxylate transporter gene.

    Alexandra M. Dumitrescu;Xiao-Hui Liao;Thomas B. Best;Knut Brockmann

  • Familial Syndrome Combining Deaf-Mutism, Stippled Epiphyses, Goiter and Abnormally High PBI: Possible Target Organ Refractoriness to Thyroid Hormone12

    Samuel Refetoff;Loren T. Dewind;Leslie J. Degroot

  • Modulation of glucose regulation and insulin secretion by circadian rhythmicity and sleep.

    E Van Cauter;J D Blackman;D Roland;J P Spire

  • Mutations in SECISBP2 result in abnormal thyroid hormone metabolism.

    Alexandra M. Dumitrescu;Xiao Hui Liao;Mohamed S.Y. Abdullah;Joaquin Lado-Abeal;Joaquin Lado-Abeal

  • Targeted Expression of BRAFV600E in Thyroid Cells of Transgenic Mice Results in Papillary Thyroid Cancers that Undergo Dedifferentiation

    Jeffrey A. Knauf;Xiaolan Ma;Eric P. Smith;Lei Zhang

  • Brief report: resistance to thyrotropin caused by mutations in the thyrotropin-receptor gene.

    Thongkum Sunthornthepvarakul;Michael E. Gottschalk;Yoshitaka Hayashi;Samuel Refetoff

  • Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation

    Debyani Chakravarty;Elmer Santos;Mabel M Ryder;Jeffrey A. Knauf

  • Generation of functional thyroid from embryonic stem cells.

    Francesco Antonica;Dominika Figini Kasprzyk;Robert Opitz;Michelina Iacovino

  • Reduced clearance rate of thyroxine-binding globulin (TBG) with increased sialylation: a mechanism for estrogen-induced elevation of serum TBG concentration.

    Kenneth B. Ain;Yuichi Mori;Samuel Refetoff

  • Resistance to thyroid hormone.

    Roy E. Weiss;Samuel Refetoff

  • Identification of the maturation factor for dual oxidase. Evolution of an eukaryotic operon equivalent

    Helmut Grasberger;Samuel Refetoff

  • Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice.

    Alexandra M. Dumitrescu;Xiao Hui Liao;Roy E. Weiss;Kathleen Millen

  • Fetal Loss Associated With Excess Thyroid Hormone Exposure

    João Anselmo;Dingcai Cao;Theodore Karrison;Roy E. Weiss

  • Syndromes of reduced sensitivity to thyroid hormone : genetic defects in hormone receptors, cell transporters and deiodination

    Samuel Refetoff;Alexandra M. Dumitrescu

  • Generalized resistance to thyroid hormone associated with a mutation in the ligand-binding domain of the human thyroid hormone receptor beta

    Akihiro Sakurai;Kyoko Takeda;Kenneth Ain;Paola Ceccarelli

  • Thyroid Hormone Induces Rapid Activation of Akt/Protein Kinase B-Mammalian Target of Rapamycin-p70S6K Cascade through Phosphatidylinositol 3-Kinase in Human Fibroblasts

    Xia Cao;Fukushi Kambe;Lars C. Moeller;Samuel Refetoff

  • Thyroid Dysfunction in Chronic Renal Failure: A STUDY OF THE PITUITARY-THYROID AXIS AND PERIPHERAL TURNOVER KINETICS OF THYROXINE AND TRIIODOTHYRONINE

    Victoria Sy Lim;Victor S. Fang;Adrian I. Katz;Samuel Refetoff

  • Continuing occurrence of thyroid carcinoma after irradiation to the neck in infancy and childhood.

    Refetoff S;Harrison J;Karanfilski Bt;Kaplan El

  • Nocturnal exercise phase delays circadian rhythms of melatonin and thyrotropin secretion in normal men.

    O. Van Reeth;J. Sturis;M. M. Byrne;J. D. Blackman

Frequent Co-Authors

Gilbert Vassart
Gilbert Vassart Université Libre de Bruxelles
Paul M. Yen
Paul M. Yen Duke University
Leslie J. DeGroot
Leslie J. DeGroot University of Chicago
Eve Van Cauter
Eve Van Cauter University of Chicago
Juan Bernal
Juan Bernal Autonomous University of Madrid
Jacques Samarut
Jacques Samarut École Normale Supérieure de Lyon
Sabine Costagliola
Sabine Costagliola Université Libre de Bruxelles
Luca Persani
Luca Persani University of Milan
Paolo Beck-Peccoz
Paolo Beck-Peccoz University of Milan
William W. Chin
William W. Chin Harvard Medical School

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