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Overview

Josef Köhrle is affiliated with Charité - University Medicine Berlin in Germany. Their research primarily focuses on the field of Medicine, with a considerable emphasis on Endocrinology, Diabetes and Metabolism, as well as Health, Toxicology and Mutagenesis, Molecular Biology, Nutrition and Dietetics, and Epidemiology.

The scientist's main research topics include:

  • Thyroid Disorders and Treatments
  • Growth Hormone and Insulin-like Growth Factors
  • Selenium in Biological Systems
  • Ion channel regulation and function
  • Thyroid Cancer Diagnosis and Treatment
  • Trace Elements in Health
  • Heavy Metal Exposure and Toxicity

Josef Köhrle has contributed extensively to academic publications. Frequent publication venues include:

  • Thyroid
  • Endocrine Abstracts
  • International Journal of Molecular Sciences
  • Free Radical Biology and Medicine
  • Frontiers in Endocrinology

Some recent significant papers authored by Köhrle are:

  • Selenium, Iodine and Iron-Essential Trace Elements for Thyroid Hormone Synthesis and Metabolism, 2023, International Journal of Molecular Sciences
  • Deiodinases control local cellular and systemic thyroid hormone availability, 2022, Free Radical Biology and Medicine
  • Thyroid hormone system disrupting chemicals, 2021, Best Practice & Research Clinical Endocrinology & Metabolism

The scientist frequently collaborates with several researchers, including:

  • Kostja Renko
  • Caroline Frädrich
  • Eddy Rijntjes
  • Eva K. Wirth
  • Lutz Schomburg

Best Publications

  • Selenium, the Thyroid, and the Endocrine System

    J Köhrle;F Jakob;Bernard Contempre;Jacques Emile Dumont

  • Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues

    Lutz Schomburg;Ulrich Schweizer;Bettina Holtmann;Leopold Flohé

  • The impact of iron and selenium deficiencies on iodine and thyroid metabolism: biochemistry and relevance to public health.

    Michael B. Zimmermann;Josef Köhrle

  • Local activation and inactivation of thyroid hormones: the deiodinase family

    Josef Köhrle

  • Selenium and brain function: a poorly recognized liaison.

    Ulrich Schweizer;Anja U Bräuer;Josef Köhrle;Robert Nitsch

  • Evaluation of the Association between Persistent Organic Pollutants (POPs) and Diabetes in Epidemiological Studies: A National Toxicology Program Workshop Review

    Kyla W. Taylor;Raymond F. Novak;Henry A. Anderson;Linda S. Birnbaum

  • On the importance of selenium and iodine metabolism for thyroid hormone biosynthesis and human health

    Lutz Schomburg;Josef Köhrle

  • The deiodinase family: selenoenzymes regulating thyroid hormone availability and action

    J. Köhrle

  • Selected Novel Flavones Inhibit the DNA Binding or the DNA Religation Step of Eukaryotic Topoisomerase I

    Fritz Boege;Tobias Straub;Albrecht Kehr;Charlotte Boesenberg

  • Selenium and thyroid.

    Josef Köhrle;Roland Gärtner

  • The trace element selenium and the thyroid gland.

    Josef Köhrle

  • Retinoic acid increases sodium/iodide symporter mRNA levels in human thyroid cancer cell lines and suppresses expression of functional symporter in nontransformed FRTL-5 rat thyroid cells.

    C. Schmutzler;R. Winzer;J. Meissner-Weigl;J. Köhrle

  • Selenium and selenoproteins in mammals: extraordinary, essential, enigmatic.

    L. Schomburg;U. Schweizer;J. Köhrle

  • Clinical impact of retinoids in redifferentiation therapy of advanced thyroid cancer: final results of a pilot study

    Simon D;Körber C;Krausch M;Segering J

  • Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration

    Eva K. Wirth;Marcus Conrad;Jochen Winterer;Christian Wozny

  • Selenoprotein Gene Nomenclature

    Vadim N. Gladyshev;Vadim N. Gladyshev;Elias S. Arnér;Marla J. Berry;Regina Brigelius-Flohé

  • Hepatically derived selenoprotein P is a key factor for kidney but not for brain selenium supply.

    Ulrich Schweizer;Florian STRECKFUß;Paco Pelt;Bradley A. Carlson

  • Circadian and pulsatile thyrotropin secretion in euthyroid man under the influence of thyroid hormone and glucocorticoid administration.

    G. Brabant;A. Brabant;U. Ranft;K. Ocran

  • Selenium and the thyroid

    Josef Köhrle

  • Neuronal 3′,3,5-Triiodothyronine (T3) Uptake and Behavioral Phenotype of Mice Deficient in Mct8, the Neuronal T3 Transporter Mutated in Allan–Herndon–Dudley Syndrome

    Eva K Wirth;Stephan Roth;Cristiane Blechschmidt;Sabine M Hölter

Frequent Co-Authors

Ulrich Schweizer
Ulrich Schweizer University of Bonn
Georg Brabant
Georg Brabant University of Lübeck
Georg Homuth
Georg Homuth Greifswald University Hospital
Uwe Völker
Uwe Völker University of Greifswald
Henry Völzke
Henry Völzke Greifswald University Hospital
Torsten Schöneberg
Torsten Schöneberg Leipzig University
Henning Dralle
Henning Dralle University of Duisburg-Essen
Andreas Bergmann
Andreas Bergmann University of Massachusetts Chan Medical School
Dolph L. Hatfield
Dolph L. Hatfield National Institutes of Health
Gerd Krause
Gerd Krause Leibniz Institute for Neurobiology

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