D-Index & Metrics Best Publications
Research.com 2022 Best Scientist Award Badge
Chemistry
Germany
2022

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 145 Citations 92,646 481 World Ranking 49 National Ranking 3
Biology and Biochemistry D-index 144 Citations 89,550 490 World Ranking 97 National Ranking 5
Best Scientists D-index 157 Citations 108,263 710 World Ranking 934 National Ranking 35

Research.com Recognitions

Awards & Achievements

2022 - Research.com Best Scientist Award

2022 - Research.com Biology and Biochemistry in Germany Leader Award

2022 - Research.com Chemistry in Germany Leader Award

2000 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Biochemistry and Biophysics

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Biochemistry
  • Gene

His primary areas of study are Biochemistry, Antioxidant, Glutathione, Carotenoid and Oxidative stress. His study in Glutathione peroxidase, Lipid peroxidation, Peroxynitrite, Ebselen and Microsome is carried out as part of his Biochemistry studies. The study incorporates disciplines such as Reactive oxygen species, Internal medicine, Pharmacology and Endocrinology in addition to Antioxidant.

His Glutathione research focuses on Efflux and how it relates to Intracellular. His Carotenoid research incorporates themes from Erythema, Photochemistry and Singlet oxygen. The various areas that Helmut Sies examines in his Oxidative stress study include Oxidative phosphorylation, Redox and Micronutrient.

His most cited work include:

  • Hydroperoxide metabolism in mammalian organs. (5003 citations)
  • Oxidative stress: oxidants and antioxidants (3496 citations)
  • Lycopene as the most efficient biological carotenoid singlet oxygen quencher. (1830 citations)

What are the main themes of his work throughout his whole career to date?

Helmut Sies mainly investigates Biochemistry, Glutathione, Antioxidant, Internal medicine and Oxidative stress. His Biochemistry research focuses on Carotenoid, Lipid peroxidation, Reactive oxygen species, Peroxynitrite and Ebselen. His study looks at the relationship between Carotenoid and fields such as Singlet oxygen, as well as how they intersect with chemical problems.

His Glutathione research integrates issues from Peroxidase and Molecular biology. Helmut Sies is interested in Vitamin E, which is a field of Antioxidant. His Oxidative stress research incorporates elements of Oxidative phosphorylation and Redox.

He most often published in these fields:

  • Biochemistry (49.93%)
  • Glutathione (18.40%)
  • Antioxidant (15.21%)

What were the highlights of his more recent work (between 2007-2021)?

  • Biochemistry (49.93%)
  • Oxidative stress (12.17%)
  • Internal medicine (14.52%)

In recent papers he was focusing on the following fields of study:

His main research concerns Biochemistry, Oxidative stress, Internal medicine, Antioxidant and Selenium. His NADPH oxidase study, which is part of a larger body of work in Biochemistry, is frequently linked to Photoprotection, bridging the gap between disciplines. His Oxidative stress research is multidisciplinary, relying on both Homeostasis, Biophysics, Reactive oxygen species, Redox and Neuroscience.

His Internal medicine research is multidisciplinary, incorporating perspectives in Gastroenterology and Endocrinology. His study in Antioxidant is interdisciplinary in nature, drawing from both Micronutrient, Carotenoid and Pharmacology. His Selenium research includes elements of Immunology and Animal science.

Between 2007 and 2021, his most popular works were:

  • Oxidative stress: a concept in redox biology and medicine. (797 citations)
  • Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress (627 citations)
  • Role of metabolic H2O2 generation: redox signaling and oxidative stress. (408 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Biochemistry

His scientific interests lie mostly in Biochemistry, Oxidative stress, Antioxidant, Internal medicine and Reactive oxygen species. Helmut Sies studies Biochemistry, focusing on NADPH oxidase in particular. While the research belongs to areas of Oxidative stress, Helmut Sies spends his time largely on the problem of Redox, intersecting his research to questions surrounding Oxidative phosphorylation, Oxidation reduction, Cellular respiration, Adaptive response and Neuroscience.

His research integrates issues of Micronutrient, Superoxide, Carotenoid and Pharmacology in his study of Antioxidant. His Internal medicine study incorporates themes from Gastroenterology and Endocrinology. His Reactive oxygen species study combines topics in areas such as Catalase and Mitochondrion.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Hydroperoxide metabolism in mammalian organs.

B Chance;H Sies;A Boveris.
Physiological Reviews (1979)

7415 Citations

Oxidative stress: oxidants and antioxidants

H Sies.
Experimental Physiology (1997)

6327 Citations

Lycopene as the most efficient biological carotenoid singlet oxygen quencher.

P Di Mascio;S Kaiser;H Sies.
Archives of Biochemistry and Biophysics (1989)

2876 Citations

Strategies of antioxidant defense

Helmut Sies.
FEBS Journal (1993)

2702 Citations

Glutathione and its role in cellular functions.

Helmut Sies.
Free Radical Biology and Medicine (1999)

2018 Citations

[48] Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples

Theodorus P.M. Akerboom;Helmut Sies.
Methods in Enzymology (1981)

1862 Citations

Oxidative stress: from basic research to clinical application.

Helmut Sies.
The American Journal of Medicine (1991)

1796 Citations

Biochemistry of Oxidative Stress

Helmut Sies.
Angewandte Chemie (1986)

1634 Citations

Vitamins E and C, beta-carotene, and other carotenoids as antioxidants.

H Sies;W Stahl.
The American Journal of Clinical Nutrition (1995)

1606 Citations

Chemistry of biologically important synthetic organoselenium compounds.

Govindasamy Mugesh;Wolf-Walther du Mont;Helmut Sies.
Chemical Reviews (2001)

1547 Citations

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