What is he best known for?
The fields of study he is best known for:
Philip D. Jeffrey mainly investigates Cell biology, Biochemistry, Ubiquitin ligase, Cyclin-dependent kinase and Protein structure.
His biological study spans a wide range of topics, including Molecular biology and Genetics, DNA.
His DNA research is multidisciplinary, incorporating perspectives in B3 domain, Binding domain, Binding site and HMG-box.
His work in Cyclin-dependent kinase covers topics such as Cyclin-dependent kinase 2 which are related to areas like Active site.
His Protein structure study combines topics from a wide range of disciplines, such as Autophagy, Apoptosis, Bcl-xL and Function.
He combines subjects such as Protein ubiquitination, Skp1 and F-box protein with his study of Ubiquitin-conjugating enzyme.
His most cited work include:
- Crystal structure of a p53 tumor suppressor-DNA complex: Understanding tumorigenic mutations (2086 citations)
- Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex (1222 citations)
- Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. (1177 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Cell biology, Biochemistry, Biophysics, Protein structure and Binding site.
His Cell biology research is multidisciplinary, relying on both Quorum sensing, Molecular biology and Apoptosis.
Philip D. Jeffrey combines topics linked to Ubiquitin ligase with his work on Biochemistry.
His Biophysics study combines topics in areas such as Endoplasmic reticulum, Vesicle and Lipid bilayer fusion.
In his work, Enzyme activator is strongly intertwined with Active site, which is a subfield of Protein structure.
His Binding site research is multidisciplinary, incorporating elements of Stereochemistry and Organelle.
He most often published in these fields:
- Cell biology (42.86%)
- Biochemistry (39.56%)
- Biophysics (17.58%)
What were the highlights of his more recent work (between 2017-2021)?
- Biophysics (17.58%)
- Vesicle (7.69%)
- Lipid bilayer fusion (6.59%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Biophysics, Vesicle, Lipid bilayer fusion, Binding site and Linker.
In his research, Philip D. Jeffrey performs multidisciplinary study on Biophysics and VPS45.
His study in Vesicle is interdisciplinary in nature, drawing from both Golgi apparatus, Endoplasmic reticulum and USE1.
Philip D. Jeffrey performs multidisciplinary study in Binding site and Pyrenoid in his work.
Linker and Carbon fixation are two areas of study in which Philip D. Jeffrey engages in interdisciplinary research.
The SNARE complex assembly study combines topics in areas such as Structural biology and Molecular biophysics.
Between 2017 and 2021, his most popular works were:
- A metagenomic strategy for harnessing the chemical repertoire of the human microbiome (25 citations)
- Structure and mechanism of pyrimidine-pyrimidone (6-4) photoproduct recognition by the Rad4/XPC nucleotide excision repair complex (19 citations)
- ParST is a widespread toxin-antitoxin module that targets nucleotide metabolism. (13 citations)
In his most recent research, the most cited papers focused on:
His primary areas of study are Biochemistry, Nucleotide excision repair, Base pair, Nucleotide-excision repair complex and Pyrimidone.
His Biochemistry research includes elements of Bacterial adhesin and Streptococcus gordonii.
His study in Nucleotide excision repair is interdisciplinary in nature, drawing from both Pyrimidine dimer and Stereochemistry.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
